MB21D2 (Mab-21 domain containing 2)

Gene

• Entrez ID: 151963
• Gene name: Mab-21 domain containing 2
• Gene symbol: MB21D2
• Synonyms (NCBI Gene): C3orf59, D2A, hMB21D2
• Chromosome: 3
• Chromosome location: 3q29

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020219	hsa-miR-130b-3p	Sequencing	20371350
MIRT031178	hsa-miR-19b-3p	Sequencing	20371350
MIRT042369	hsa-miR-484	CLASH	23622248
MIRT566809	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT566808	hsa-miR-4517	PAR-CLIP	20371350
MIRT566807	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT566806	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT566805	hsa-miR-6847-5p	PAR-CLIP	20371350
MIRT566804	hsa-miR-4257	PAR-CLIP	20371350
MIRT566803	hsa-miR-1827	PAR-CLIP	20371350
MIRT400560	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT031178	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT020219	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT556229	hsa-miR-3666	PAR-CLIP	21572407
MIRT556228	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT556227	hsa-miR-4295	PAR-CLIP	21572407
MIRT556226	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT556225	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT556224	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT556223	hsa-miR-5692a	PAR-CLIP	21572407
MIRT556222	hsa-miR-5197-5p	PAR-CLIP	21572407
MIRT091421	hsa-miR-944	PAR-CLIP	21572407
MIRT556221	hsa-miR-302b-5p	PAR-CLIP	21572407
MIRT556220	hsa-miR-302d-5p	PAR-CLIP	21572407
MIRT556219	hsa-miR-4470	PAR-CLIP	21572407
MIRT556218	hsa-miR-567	PAR-CLIP	21572407
MIRT556217	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT556216	hsa-miR-22-5p	PAR-CLIP	21572407
MIRT556215	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT556214	hsa-miR-4473	PAR-CLIP	21572407
MIRT091416	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT091420	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT556213	hsa-miR-4677-5p	PAR-CLIP	21572407
MIRT440271	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440271	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT566809	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT566808	hsa-miR-4517	PAR-CLIP	20371350
MIRT566807	hsa-miR-1910-3p	PAR-CLIP	20371350
MIRT566806	hsa-miR-6511a-5p	PAR-CLIP	20371350
MIRT566805	hsa-miR-6847-5p	PAR-CLIP	20371350
MIRT566804	hsa-miR-4257	PAR-CLIP	20371350
MIRT566803	hsa-miR-1827	PAR-CLIP	20371350
MIRT400560	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT031178	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT020219	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT556229	hsa-miR-3666	PAR-CLIP	21572407
MIRT556228	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT556227	hsa-miR-4295	PAR-CLIP	21572407
MIRT556226	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT556225	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT556224	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT556223	hsa-miR-5692a	PAR-CLIP	21572407
MIRT556222	hsa-miR-5197-5p	PAR-CLIP	21572407
MIRT091421	hsa-miR-944	PAR-CLIP	21572407
MIRT556221	hsa-miR-302b-5p	PAR-CLIP	21572407
MIRT556220	hsa-miR-302d-5p	PAR-CLIP	21572407
MIRT556219	hsa-miR-4470	PAR-CLIP	21572407
MIRT556218	hsa-miR-567	PAR-CLIP	21572407
MIRT556217	hsa-miR-2116-5p	PAR-CLIP	21572407
MIRT556216	hsa-miR-22-5p	PAR-CLIP	21572407
MIRT556215	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT556214	hsa-miR-4473	PAR-CLIP	21572407
MIRT091416	hsa-miR-374a-5p	PAR-CLIP	21572407
MIRT091420	hsa-miR-374b-5p	PAR-CLIP	21572407
MIRT556213	hsa-miR-4677-5p	PAR-CLIP	21572407
MIRT1134761	hsa-miR-2355-5p	CLIP-seq
MIRT1134762	hsa-miR-3143	CLIP-seq
MIRT1134763	hsa-miR-3146	CLIP-seq
MIRT1134764	hsa-miR-3679-3p	CLIP-seq
MIRT1134765	hsa-miR-3978	CLIP-seq
MIRT1134766	hsa-miR-4261	CLIP-seq
MIRT1134767	hsa-miR-4282	CLIP-seq
MIRT1134768	hsa-miR-4446-5p	CLIP-seq
MIRT1134769	hsa-miR-4662a-3p	CLIP-seq
MIRT1134770	hsa-miR-4719	CLIP-seq
MIRT1134771	hsa-miR-543	CLIP-seq
MIRT2038326	hsa-miR-34c-3p	CLIP-seq
MIRT2038327	hsa-miR-3908	CLIP-seq
MIRT2038328	hsa-miR-3922-5p	CLIP-seq
MIRT2038329	hsa-miR-3942-5p	CLIP-seq
MIRT2038330	hsa-miR-3973	CLIP-seq
MIRT2038331	hsa-miR-4307	CLIP-seq
MIRT2038332	hsa-miR-4668-3p	CLIP-seq
MIRT2038333	hsa-miR-4703-5p	CLIP-seq
MIRT2038334	hsa-miR-4753-5p	CLIP-seq
MIRT2038335	hsa-miR-4766-3p	CLIP-seq
MIRT2038336	hsa-miR-520g	CLIP-seq
MIRT2038337	hsa-miR-520h	CLIP-seq
MIRT2038338	hsa-miR-561	CLIP-seq
MIRT2038339	hsa-miR-607	CLIP-seq
MIRT2268162	hsa-miR-1284	CLIP-seq
MIRT2268163	hsa-miR-1287	CLIP-seq
MIRT2268164	hsa-miR-181a	CLIP-seq
MIRT2268165	hsa-miR-181b	CLIP-seq
MIRT2268166	hsa-miR-181c	CLIP-seq
MIRT2268167	hsa-miR-181d	CLIP-seq
MIRT2268168	hsa-miR-190	CLIP-seq
MIRT2268169	hsa-miR-190b	CLIP-seq
MIRT2268170	hsa-miR-3145-3p	CLIP-seq
MIRT2268171	hsa-miR-3148	CLIP-seq
MIRT2268172	hsa-miR-3201	CLIP-seq
MIRT2268173	hsa-miR-3652	CLIP-seq
MIRT2268174	hsa-miR-380	CLIP-seq
MIRT2268175	hsa-miR-3929	CLIP-seq
MIRT2268176	hsa-miR-4262	CLIP-seq
MIRT2268177	hsa-miR-4419b	CLIP-seq
MIRT2268178	hsa-miR-4430	CLIP-seq
MIRT2268179	hsa-miR-4478	CLIP-seq
MIRT2268180	hsa-miR-4495	CLIP-seq
MIRT2268181	hsa-miR-4520a-3p	CLIP-seq
MIRT2268182	hsa-miR-4520b-3p	CLIP-seq
MIRT2268183	hsa-miR-4529-3p	CLIP-seq
MIRT1134769	hsa-miR-4662a-3p	CLIP-seq
MIRT2268184	hsa-miR-4715-3p	CLIP-seq
MIRT1134770	hsa-miR-4719	CLIP-seq
MIRT2268185	hsa-miR-4775	CLIP-seq
MIRT2268186	hsa-miR-4780	CLIP-seq
MIRT2268187	hsa-miR-4791	CLIP-seq
MIRT2268188	hsa-miR-587	CLIP-seq
MIRT2268189	hsa-miR-645	CLIP-seq
MIRT2268190	hsa-miR-654-3p	CLIP-seq
MIRT2268191	hsa-miR-942	CLIP-seq
MIRT2390661	hsa-miR-3074-5p	CLIP-seq
MIRT2567863	hsa-miR-130a	CLIP-seq
MIRT2567864	hsa-miR-130b	CLIP-seq
MIRT2567865	hsa-miR-1343	CLIP-seq
MIRT2567866	hsa-miR-19a	CLIP-seq
MIRT2567867	hsa-miR-19b	CLIP-seq
MIRT2567868	hsa-miR-2110	CLIP-seq
MIRT2567869	hsa-miR-2116	CLIP-seq
MIRT2567870	hsa-miR-301a	CLIP-seq
MIRT2567871	hsa-miR-301b	CLIP-seq
MIRT2390661	hsa-miR-3074-5p	CLIP-seq
MIRT2567872	hsa-miR-3140-3p	CLIP-seq
MIRT2268170	hsa-miR-3145-3p	CLIP-seq
MIRT2567873	hsa-miR-3150a-3p	CLIP-seq
MIRT2567874	hsa-miR-3159	CLIP-seq
MIRT2567875	hsa-miR-3646	CLIP-seq
MIRT2567876	hsa-miR-3662	CLIP-seq
MIRT2567877	hsa-miR-374a	CLIP-seq
MIRT2567878	hsa-miR-374b	CLIP-seq
MIRT2038327	hsa-miR-3908	CLIP-seq
MIRT2038329	hsa-miR-3942-5p	CLIP-seq
MIRT2567879	hsa-miR-4260	CLIP-seq
MIRT2567880	hsa-miR-4450	CLIP-seq
MIRT2567881	hsa-miR-454	CLIP-seq
MIRT2567882	hsa-miR-4698	CLIP-seq
MIRT2038333	hsa-miR-4703-5p	CLIP-seq
MIRT2268184	hsa-miR-4715-3p	CLIP-seq
MIRT2038335	hsa-miR-4766-3p	CLIP-seq
MIRT2567883	hsa-miR-633	CLIP-seq
MIRT2567863	hsa-miR-130a	CLIP-seq
MIRT2567864	hsa-miR-130b	CLIP-seq
MIRT2567865	hsa-miR-1343	CLIP-seq
MIRT2567866	hsa-miR-19a	CLIP-seq
MIRT2567867	hsa-miR-19b	CLIP-seq
MIRT2567870	hsa-miR-301a	CLIP-seq
MIRT2567871	hsa-miR-301b	CLIP-seq
MIRT2390661	hsa-miR-3074-5p	CLIP-seq
MIRT2567872	hsa-miR-3140-3p	CLIP-seq
MIRT2268170	hsa-miR-3145-3p	CLIP-seq
MIRT2038327	hsa-miR-3908	CLIP-seq
MIRT2038329	hsa-miR-3942-5p	CLIP-seq
MIRT2567881	hsa-miR-454	CLIP-seq
MIRT2038333	hsa-miR-4703-5p	CLIP-seq
MIRT2268184	hsa-miR-4715-3p	CLIP-seq
MIRT2038335	hsa-miR-4766-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0016740	Function	Transferase activity	IEA
GO:0016779	Function	Nucleotidyltransferase activity	IEA
GO:0044877	Function	Protein-containing complex binding	IDA	23209302
GO:0045296	Function	Cadherin binding	HDA	25468996

Other IDs

• MIM: 620914
• HGNC: 30438
• e!Ensembl: ENSG00000180611

Protein

• UniProt ID: Q8IYB1
• Protein name: Nucleotidyltransferase MB21D2 (EC 2.7.7.-) (Mab-21 domain-containing protein 2) (hMB21D2)
• Protein function: Probable nucleotidyltransferase that catalyzes the formation of cyclic dinucleotide second messenger in response to some unknown stimulus.
• PDB: 7LT1
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03281	Mab-21	108 → 402	Mab-21 protein	Family

• Sequence:

  MKMAAPTANKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIH
  TAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTL
  LVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFS
  PTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVS
  FKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKK
  CISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLG
  LIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKA
  ANRLTLELQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVT
  RPHFRIDDKFF

• Sequence length: 491