Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	151613
Gene name	Tetratricopeptide repeat domain 14
Gene symbol	TTC14
Synonyms (NCBI Gene)	DRDL5813PRO19630
Chromosome	3
Chromosome location	3q26.33

Show/Hide all (74)

miRTarBase ID	miRNA	Experiments	Reference
MIRT465051	hsa-miR-5197-3p	PAR-CLIP	23592263
MIRT465050	hsa-miR-3125	PAR-CLIP	23592263
MIRT465049	hsa-miR-3916	PAR-CLIP	23592263
MIRT465048	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT465047	hsa-miR-1272	PAR-CLIP	23592263
MIRT465046	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT465045	hsa-miR-3682-3p	PAR-CLIP	23592263
MIRT465044	hsa-miR-6077	PAR-CLIP	23592263
MIRT465043	hsa-miR-7973	PAR-CLIP	23592263
MIRT465042	hsa-miR-6808-3p	PAR-CLIP	23592263
MIRT465051	hsa-miR-5197-3p	PAR-CLIP	23592263
MIRT465050	hsa-miR-3125	PAR-CLIP	23592263
MIRT465049	hsa-miR-3916	PAR-CLIP	23592263
MIRT465048	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT465047	hsa-miR-1272	PAR-CLIP	23592263
MIRT465046	hsa-miR-3605-5p	PAR-CLIP	23592263
MIRT465045	hsa-miR-3682-3p	PAR-CLIP	23592263
MIRT465044	hsa-miR-6077	PAR-CLIP	23592263
MIRT465043	hsa-miR-7973	PAR-CLIP	23592263
MIRT465042	hsa-miR-6808-3p	PAR-CLIP	23592263
MIRT1460848	hsa-miR-1256	CLIP-seq
MIRT1460849	hsa-miR-1271	CLIP-seq
MIRT1460850	hsa-miR-15a	CLIP-seq
MIRT1460851	hsa-miR-15b	CLIP-seq
MIRT1460852	hsa-miR-16	CLIP-seq
MIRT1460853	hsa-miR-182	CLIP-seq
MIRT1460854	hsa-miR-195	CLIP-seq
MIRT1460855	hsa-miR-3908	CLIP-seq
MIRT1460856	hsa-miR-424	CLIP-seq
MIRT1460857	hsa-miR-4642	CLIP-seq
MIRT1460858	hsa-miR-485-3p	CLIP-seq
MIRT1460859	hsa-miR-497	CLIP-seq
MIRT1460860	hsa-miR-539	CLIP-seq
MIRT1460861	hsa-miR-570	CLIP-seq
MIRT1460862	hsa-miR-96	CLIP-seq
MIRT1460850	hsa-miR-15a	CLIP-seq
MIRT1460851	hsa-miR-15b	CLIP-seq
MIRT1460852	hsa-miR-16	CLIP-seq
MIRT1460854	hsa-miR-195	CLIP-seq
MIRT1460855	hsa-miR-3908	CLIP-seq
MIRT1460856	hsa-miR-424	CLIP-seq
MIRT1460859	hsa-miR-497	CLIP-seq
MIRT2138419	hsa-miR-664	CLIP-seq
MIRT1460850	hsa-miR-15a	CLIP-seq
MIRT1460851	hsa-miR-15b	CLIP-seq
MIRT1460852	hsa-miR-16	CLIP-seq
MIRT1460854	hsa-miR-195	CLIP-seq
MIRT2359320	hsa-miR-300	CLIP-seq
MIRT2359321	hsa-miR-381	CLIP-seq
MIRT1460855	hsa-miR-3908	CLIP-seq
MIRT1460856	hsa-miR-424	CLIP-seq
MIRT2359322	hsa-miR-4263	CLIP-seq
MIRT2359323	hsa-miR-4666-3p	CLIP-seq
MIRT2359324	hsa-miR-4799-5p	CLIP-seq
MIRT1460859	hsa-miR-497	CLIP-seq
MIRT2359325	hsa-miR-576-5p	CLIP-seq
MIRT2652533	hsa-miR-1283	CLIP-seq
MIRT2652534	hsa-miR-216a	CLIP-seq
MIRT2652535	hsa-miR-216b	CLIP-seq
MIRT2652536	hsa-miR-3074-5p	CLIP-seq
MIRT2652537	hsa-miR-3675-3p	CLIP-seq
MIRT2652538	hsa-miR-4282	CLIP-seq
MIRT2652539	hsa-miR-4422	CLIP-seq
MIRT2652540	hsa-miR-4684-5p	CLIP-seq
MIRT2652541	hsa-miR-4775	CLIP-seq
MIRT2652542	hsa-miR-486-5p	CLIP-seq
MIRT2652543	hsa-miR-494	CLIP-seq
MIRT1460860	hsa-miR-539	CLIP-seq
MIRT2652544	hsa-miR-548ae	CLIP-seq
MIRT2652545	hsa-miR-548aj	CLIP-seq
MIRT2652546	hsa-miR-548am	CLIP-seq
MIRT2652547	hsa-miR-548x	CLIP-seq
MIRT2652548	hsa-miR-580	CLIP-seq
MIRT2652549	hsa-miR-590-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q96N46

Protein name

Tetratricopeptide repeat protein 14 (TPR repeat protein 14)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF13414	TPR_11	314 → 355		Repeat

Sequence

MDRDLLRQSLNCHGSSLLSLLRSEQQDNPHFRSLLGSAAEPARGPPPQHPLQGRKEKRVD
NIEIQKFISKKADLLFALSWKSDAPATSEINEDSEDHYAIMPPLEQFMEIPSMDRRELFF
RDIERGDIVIGRISSIREFGFFMVLICLGSGIMRDIAHLEITALCPLRDVPSHSNHGDPL
SYYQTGDIIRAGIKDIDRYHEKLAVSLYSSSLPPHLSGIKLGVISSEELPLYYRRSVELN
SNSLESYENVMQSSLGFVNPGVVEFLLEKLGIDESNPPSLMRGLQSKNFSEDDFASALRK
KQSASWALKCVKIGVDYFKVGRHVDAMNEYNKALEIDKQNVEALVARGALYATKGSLNKA
IEDFELALENCPTHRNARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAED
ALQKLHKYMQKSLELREKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRRKSTSSSS
VSSADESVSSSSSSSSSGHKRHKKHKRNRSESSRSSRRHSSRASSNQIDQNRKDECYPVP
ANTSASFLNHKQEVEKLLGKQDRLQYEKTQIKEKDRCPLSSSSLEIPDDFGGRSEDPRDF
YNSYKTQAGSSKTEKPYKSERHFSSRRNSSDSFCRNSEDKIYGYRRFEKDIEGRKEHYRR
WEPGSVRHSTSPASSEYSWKSVEKYKKYAHSGSRDFSRHEQRYRLNTNQGEYEREDNYGE
DIKTEVPEEDALSSKEHSESSVKKNLPQNLLNIFNQIAEFEKEKGNKSKN

Sequence length

770

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CILIARY DYSKINESIA, PRIMARY, 14	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CILIARY MOTILITY DISORDERS	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TTC14-related disorder	Benign; Likely benign; Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Multiple Myeloma	Associate	37610069	★★★★★ ★☆☆☆☆ Found in Text Mining only

TTC14 (tetratricopeptide repeat domain 14)