GPR155 (G protein-coupled receptor 155)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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151556 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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G protein-coupled receptor 155 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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GPR155 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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DEP.7, DEPDC3, LYCHOS, PGR22 |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q31.1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||||||||||||
UniProt ID | Q7Z3F1 | ||||||||||||||||||||
Protein name | Lysosomal cholesterol signaling protein (LYCHOS) (G-protein coupled receptor PGR22) | ||||||||||||||||||||
Protein function | Cholesterol-binding protein that acts as a regulator of mTORC1 signaling pathway (PubMed:36007018). Acts as a sensor of cholesterol to signal cholesterol sufficiency to mTORC1: in presence of cholesterol, binds cholesterol, leading to disruption | ||||||||||||||||||||
PDB | 8U54 , 8U56 , 8U58 , 8U5C , 8U5N , 8U5Q , 8U5V , 8U5X , 8WR3 , 8Y56 , 8Z8Z | ||||||||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 870 | ||||||||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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