MSL3B (MSL complex subunit 3B)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
151507
Gene name Gene Name - the full gene name approved by the HGNC.
MSL complex subunit 3B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MSL3B
Synonyms (NCBI Gene) Gene synonyms aliases
MSL3L2, MSL3P1
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2q37.1
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(5)
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IEA
GO:0006325 Process Chromatin organization IEA
GO:0006355 Process Regulation of DNA-templated transcription IEA
GO:0035267 Component NuA4 histone acetyltransferase complex IBA
GO:0072487 Component MSL complex IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID P0C860
Protein name MSL complex subunit 3B (Male-specific lethal-3 homolog 2) (Male-specific lethal-3 homolog pseudogene 1) (Male-specific lethal-3 protein-like 2) (MSL3-like 2)
Protein function Probable non-catalytic component of the MSL histone acetyltransferase complex, a multiprotein complex that mediates the majority of histone H4 acetylation at 'Lys-16' (H4K16ac), an epigenetic mark that prevents chromatin compaction. {ECO:0000250
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05712 MRG 77 → 430 MRG Family
Sequence
Sequence length 447
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Dermatitis Atopic dermatitis (moderate to severe) N/A N/A GWAS