CATSPERT (catsper channel auxiliary subunit tau)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID 151254
Gene name Catsper channel auxiliary subunit tau
Gene symbol CATSPERT
Synonyms (NCBI Gene)
ALS2CR11C2CD6SPGF68
Chromosome 2
Chromosome location 2q33.1
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all (12)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 32296183
GO:0005886 Component Plasma membrane IEA
GO:0005929 Component Cilium IEA
GO:0007283 Process Spermatogenesis ISS
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
619776 14438 ENSG00000155754
Protein Protein information from UniProt database.
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q53TS8
Protein name Cation channel sperm-associated targeting subunit tau (CatSper-tau) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein) (C2 calcium-dependent domain-containing protein 6)
Protein function Auxiliary component of the CatSper complex, a complex involved in sperm cell hyperactivation. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization. Required for CatSper com
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15729 ALS2CR11 84 → 502 Amyotrophic lateral sclerosis 2 candidate 11 Family
Tissue specificity TISSUE SPECIFICITY: Expressed in testis (at protein level). {ECO:0000269|PubMed:34998468}.
Sequence
Sequence length 623
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Prostate cancer Uncertain significance rs193920769 RCV000149084