Gene Gene information from NCBI Gene database.
Entrez ID 151194
Gene name Methyltransferase 21A, HSPA lysine
Gene symbol METTL21A
Synonyms (NCBI Gene)
FAM119AHCA557bHSPA-KMT
Chromosome 2
Chromosome location 2q33.3
miRNA miRNA information provided by mirtarbase database.
1194
miRTarBase ID miRNA Experiments Reference
MIRT045232 hsa-miR-186-5p CLASH 23622248
MIRT720984 hsa-miR-6776-3p HITS-CLIP 19536157
MIRT720983 hsa-miR-6746-3p HITS-CLIP 19536157
MIRT720982 hsa-miR-1306-5p HITS-CLIP 19536157
MIRT720981 hsa-miR-4772-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21516116, 23921388, 25416956, 29892012, 31515488, 32296183
GO:0005654 Component Nucleoplasm TAS
GO:0005737 Component Cytoplasm IEA
GO:0005829 Component Cytosol IBA
GO:0006479 Process Protein methylation IDA 22948820, 23349634
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615257 30476 ENSG00000144401
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WXB1
Protein name Protein N-lysine methyltransferase METTL21A (EC 2.1.1.-) (HSPA lysine methyltransferase) (HSPA-KMT) (Hepatocellular carcinoma-associated antigen 557b) (Methyltransferase-like protein 21A)
Protein function Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-
PDB 4LEC
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10294 Methyltransf_16 25 190 Lysine methyltransferase Family
Sequence
Sequence length 218
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Protein methylation