Gene Gene information from NCBI Gene database.
Entrez ID 149603
Gene name Ring finger protein 187
Gene symbol RNF187
Synonyms (NCBI Gene)
RACO-1RACO1
Chromosome 1
Chromosome location 1q42.13
miRNA miRNA information provided by mirtarbase database.
553
miRTarBase ID miRNA Experiments Reference
MIRT029670 hsa-miR-26b-5p Microarray 19088304
MIRT048702 hsa-miR-99a-5p CLASH 23622248
MIRT047251 hsa-miR-181b-5p CLASH 23622248
MIRT040880 hsa-miR-18a-3p CLASH 23622248
MIRT711041 hsa-miR-181a-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
18
GO ID Ontology Definition Evidence Reference
GO:0004842 Function Ubiquitin-protein transferase activity IDA 20852630
GO:0005515 Function Protein binding IPI 20852630, 32296183
GO:0005634 Component Nucleus IDA 20852630
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
613754 27146 ENSG00000168159
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5TA31
Protein name E3 ubiquitin-protein ligase RNF187 (EC 2.3.2.27) (RING domain AP1 coactivator 1) (RACO-1) (RING finger protein 187) (RING-type E3 ubiquitin transferase RNF187)
Protein function E3 ubiquitin-protein ligase that acts as a coactivator of JUN-mediated gene activation in response to growth factor signaling via the MAP3K1 pathway, independently from MAPK8.
PDB 7OW2
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00097 zf-C3HC4 12 52 Zinc finger, C3HC4 type (RING finger) Domain
Sequence
MALPAGPAEAACALCQRAPREPVRADCGHRFCRACVVRFWAEEDGPFPCPECADDCWQRA
VEPGRPPLSRRLLALEEAAAAPARDGPASEAALQLLCRADAGPLCAACRMAAGPEPPEWE
PRWRKALRGKENKGSVEIMRKDLNDARDLHGQAESAAAVWKGHVMDRRKKALTDYKKLRA
FFVEEEEHFLQEAEKEEGLPEDELADPTERFRSLLQAVSELEKKHRNLGLSMLLQ
Sequence length 235
Interactions View interactions