SLC30A7 (solute carrier family 30 member 7)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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148867 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 30 member 7 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC30A7 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ZHS, ZNT7, ZnT-7, ZnTL2 |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p21.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Zinc functions as a cofactor for numerous enzymes, nuclear factors, and hormones and as an intra- and intercellular signal ion. Members of the zinc transporter (ZNT)/SLC30 subfamily of the cation diffusion facilitator family, such as SLC30A7, permit cellu |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q8NEW0 | ||||||||||
| Protein name | Zinc transporter 7 (ZnT-7) (Solute carrier family 30 member 7) (Znt-like transporter 2) | ||||||||||
| Protein function | Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway (PubMed:15525635, PubMed:15994300). By contributing to zinc ion homeostasis within the early secretory pathway, regulates the act | ||||||||||
| PDB | 8J7T , 8J7U , 8J7V , 8J7W , 8J7X , 8J7Y , 8J80 | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in megakaryocytes and other bone marrow cells and in the epithelium of the small intestine. Expressed in testis (in Leydig cells), adrenal gland (in adrenal medula, zona fasciculata and zona of reticularis), and pituit | ||||||||||
| Sequence |
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| Sequence length | 376 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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