Gene Gene information from NCBI Gene database.
Entrez ID 147694
Gene name Zinc finger protein 548
Gene symbol ZNF548
Synonyms (NCBI Gene)
-
Chromosome 19
Chromosome location 19q13.43
miRNA miRNA information provided by mirtarbase database.
746
miRTarBase ID miRNA Experiments Reference
MIRT022771 hsa-miR-124-3p Microarray 18668037
MIRT029691 hsa-miR-26b-5p Microarray 19088304
MIRT693330 hsa-miR-490-3p HITS-CLIP 23313552
MIRT693329 hsa-miR-7851-3p HITS-CLIP 23313552
MIRT693328 hsa-miR-383-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IBA
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8NEK5
Protein name Zinc finger protein 548
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 7 48 KRAB box Family
PF00096 zf-C2H2 197 219 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 225 247 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 253 275 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 281 303 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 309 331 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 337 359 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 365 387 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 393 415 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 421 443 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 449 471 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 477 499 Zinc finger, C2H2 type Domain
Sequence
MNLTEGRVVFEDVAIYFSQEEWGHLDEAQRLLYRDVMLENLALLSSLGSWHGAEDEEAPS
QQGFSVGVSEVTASKPCLSSQKVHPSETCGPPLKDILCLVEHNGIHPEQHIYICEAELFQ
HPKQQIGENLSRGDDWIPSFGKNHRVHMAEEIFTCMEGWKDLPATSCLLQHQGPQSEWKP
YRDTEDREAFQTGQNDYKCSECGKTFTCSYSFVEHQKIHTGERSYECNKCGKFFKYSANF
MKHQTVH
TSERTYECRECGKSFMYNYRLMRHKRVHTGERPYECNTCGKFFRYSSTFVRHQ
RVH
TGERPYECRECGKFFMDSSTLIKHQRVHTGERPYKCNDCGKFFRYISTLIRHQRIHT
GERPYECSVCGELFRYNSSLVKHWRNHTGERPYKCSECGKSFRYHCRLIRHQRVHTGERP
YECSECGKFFRYNSNLIKHWRNHTGERPYECRECGKAFSHKHILVEHQKIHSGERPYECS
ECQKAFIRKSHLVHHQKIH
SEERLVCSMNVGNSLAKTPTSLNIRDFTMEKVYH
Sequence length 533
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
RESTLESS LEGS SYNDROME GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations