Gene Gene information from NCBI Gene database.
Entrez ID 146198
Gene name ZFP90 zinc finger protein
Gene symbol ZFP90
Synonyms (NCBI Gene)
FIKNK10ZNF756zfp-90
Chromosome 16
Chromosome location 16q22.1
Summary This gene encodes a member of the zinc finger protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the developmen
miRNA miRNA information provided by mirtarbase database.
364
miRTarBase ID miRNA Experiments Reference
MIRT045216 hsa-miR-186-5p CLASH 23622248
MIRT1511789 hsa-miR-1178 CLIP-seq
MIRT1511790 hsa-miR-1182 CLIP-seq
MIRT1511791 hsa-miR-1183 CLIP-seq
MIRT1511792 hsa-miR-1205 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
16
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
GO:0003677 Function DNA binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609451 23329 ENSG00000184939
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TF47
Protein name Zinc finger protein 90 homolog (Zfp-90) (Zinc finger protein 756)
Protein function Inhibits the transcriptional repressor activity of REST by inhibiting its binding to DNA, thereby derepressing transcription of REST target genes. ; [Isoform 2]: Acts as a bridge between FOXP3 and the core
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 13 54 KRAB box Family
PF00096 zf-C2H2 211 233 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 282 304 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 310 332 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 338 360 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 366 388 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 394 416 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 450 472 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 497 519 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 525 547 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 553 575 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 581 603 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 609 631 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in heart (PubMed:21284946). Isoform 2: Highly expressed in regulatory T-cells (Treg) (PubMed:23543754). {ECO:0000269|PubMed:21284946, ECO:0000269|PubMed:23543754}.
Sequence
MAPRPPTAAPQESVTFKDVSVDFTQEEWYHVDPAQRSLYRDVMLENYSHLVSLGYQVSKP
EVIFKLEQGEEPWISEGEIQRPFYPDWKTRPEVKSSHLQQDVSEVSHCTHDLLHATLEDS
WDVSSQLDRQQENWKRHLGSEASTQKKIITPQENFEQNKFGENSRLNTNLVTQLNIPARI
RPSECETLGSNLGHNADLLNENNILAKKKPYKCDKCRKAFIHRSSLTKHEKTHKGEGAFP
NGTDQGIYPGKKHHECTDCGKTFLWKTQLTEHQRIHTGEKPFECNVCGKAFRHSSSLGQH
ENAH
TGEKPYQCSLCGKAFQRSSSLVQHQRIHTGEKPYRCNLCGRSFRHGTSLTQHEVTH
SGEKPFQCKECGKAFSRCSSLVQHERTHTGEKPFECSICGRAFGQSPSLYKHMRIHKRGK
PYQSSNYSIDFKHSTSLTQDESTLTEVKSYHCNDCGEDFSHITDFTDHQRIHTAENPYDC
EQAFSQQAISHPGEKPYQCNVCGKAFKRSTSFIEHHRIHTGEKPYECNECGEAFSRRSSL
TQHERTH
TGEKPYECIDCGKAFSQSSSLIQHERTHTGEKPYECNECGRAFRKKTNLHDHQ
RIH
TGEKPYSCKECGKNFSRSSALTKHQRIHTRNKL
Sequence length 636
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway