C2CD4A (C2 calcium dependent domain containing 4A)

Gene

• Entrez ID: 145741
• Gene name: C2 calcium dependent domain containing 4A
• Gene symbol: C2CD4A
• Synonyms (NCBI Gene): FAM148A, NLF1
• Chromosome: 15
• Chromosome location: 15q22.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052623	hsa-let-7a-5p	CLASH	23622248
MIRT659974	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT659973	hsa-miR-494-3p	HITS-CLIP	23824327
MIRT659972	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT659971	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT659970	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT441048	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT441049	hsa-miR-376a-3p	HITS-CLIP	24374217
MIRT441048	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT441049	hsa-miR-376a-3p	HITS-CLIP	24374217
MIRT659974	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT659973	hsa-miR-494-3p	HITS-CLIP	23824327
MIRT659972	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT659971	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT659970	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT845362	hsa-let-7a	CLIP-seq
MIRT845363	hsa-let-7b	CLIP-seq
MIRT845364	hsa-let-7c	CLIP-seq
MIRT845365	hsa-let-7d	CLIP-seq
MIRT845366	hsa-let-7e	CLIP-seq
MIRT845367	hsa-let-7f	CLIP-seq
MIRT845368	hsa-let-7g	CLIP-seq
MIRT845369	hsa-let-7i	CLIP-seq
MIRT845370	hsa-miR-1228	CLIP-seq
MIRT845371	hsa-miR-1253	CLIP-seq
MIRT845372	hsa-miR-128	CLIP-seq
MIRT845373	hsa-miR-133a	CLIP-seq
MIRT845374	hsa-miR-133b	CLIP-seq
MIRT845375	hsa-miR-1343	CLIP-seq
MIRT845376	hsa-miR-141	CLIP-seq
MIRT845377	hsa-miR-142-5p	CLIP-seq
MIRT845378	hsa-miR-144	CLIP-seq
MIRT845379	hsa-miR-1913	CLIP-seq
MIRT845380	hsa-miR-200a	CLIP-seq
MIRT845381	hsa-miR-202	CLIP-seq
MIRT845382	hsa-miR-2276	CLIP-seq
MIRT845383	hsa-miR-27a	CLIP-seq
MIRT845384	hsa-miR-27b	CLIP-seq
MIRT845385	hsa-miR-3065-5p	CLIP-seq
MIRT845386	hsa-miR-3148	CLIP-seq
MIRT845387	hsa-miR-3168	CLIP-seq
MIRT845388	hsa-miR-324-3p	CLIP-seq
MIRT845389	hsa-miR-3607-5p	CLIP-seq
MIRT845390	hsa-miR-3688-3p	CLIP-seq
MIRT845391	hsa-miR-376a	CLIP-seq
MIRT845392	hsa-miR-376b	CLIP-seq
MIRT845393	hsa-miR-378g	CLIP-seq
MIRT845394	hsa-miR-3919	CLIP-seq
MIRT845395	hsa-miR-3927	CLIP-seq
MIRT845396	hsa-miR-4433	CLIP-seq
MIRT845397	hsa-miR-4437	CLIP-seq
MIRT845398	hsa-miR-4451	CLIP-seq
MIRT845399	hsa-miR-4458	CLIP-seq
MIRT845400	hsa-miR-4459	CLIP-seq
MIRT845401	hsa-miR-4500	CLIP-seq
MIRT845402	hsa-miR-4674	CLIP-seq
MIRT845403	hsa-miR-4707-3p	CLIP-seq
MIRT845404	hsa-miR-4756-3p	CLIP-seq
MIRT845405	hsa-miR-4768-3p	CLIP-seq
MIRT845406	hsa-miR-4786-3p	CLIP-seq
MIRT845407	hsa-miR-4793-3p	CLIP-seq
MIRT845408	hsa-miR-487a	CLIP-seq
MIRT845409	hsa-miR-500a	CLIP-seq
MIRT845410	hsa-miR-505	CLIP-seq
MIRT845411	hsa-miR-508-5p	CLIP-seq
MIRT845412	hsa-miR-513a-5p	CLIP-seq
MIRT845413	hsa-miR-580	CLIP-seq
MIRT845414	hsa-miR-592	CLIP-seq
MIRT845415	hsa-miR-597	CLIP-seq
MIRT845416	hsa-miR-599	CLIP-seq
MIRT845417	hsa-miR-610	CLIP-seq
MIRT845418	hsa-miR-661	CLIP-seq
MIRT845419	hsa-miR-766	CLIP-seq
MIRT845420	hsa-miR-98	CLIP-seq
MIRT1950749	hsa-miR-1184	CLIP-seq
MIRT1950750	hsa-miR-122	CLIP-seq
MIRT1950751	hsa-miR-1307	CLIP-seq
MIRT845375	hsa-miR-1343	CLIP-seq
MIRT845379	hsa-miR-1913	CLIP-seq
MIRT1950752	hsa-miR-1915	CLIP-seq
MIRT1950753	hsa-miR-192	CLIP-seq
MIRT1950754	hsa-miR-215	CLIP-seq
MIRT1950755	hsa-miR-3155	CLIP-seq
MIRT1950756	hsa-miR-3155b	CLIP-seq
MIRT1950757	hsa-miR-3198	CLIP-seq
MIRT845388	hsa-miR-324-3p	CLIP-seq
MIRT1950758	hsa-miR-3663-5p	CLIP-seq
MIRT1950759	hsa-miR-371-5p	CLIP-seq
MIRT1950760	hsa-miR-371b-5p	CLIP-seq
MIRT845393	hsa-miR-378g	CLIP-seq
MIRT1950761	hsa-miR-4274	CLIP-seq
MIRT1950762	hsa-miR-4284	CLIP-seq
MIRT1950763	hsa-miR-4309	CLIP-seq
MIRT1950764	hsa-miR-4418	CLIP-seq
MIRT1950765	hsa-miR-4423-5p	CLIP-seq
MIRT845397	hsa-miR-4437	CLIP-seq
MIRT1950766	hsa-miR-4519	CLIP-seq
MIRT1950767	hsa-miR-4638-5p	CLIP-seq
MIRT845402	hsa-miR-4674	CLIP-seq
MIRT845403	hsa-miR-4707-3p	CLIP-seq
MIRT1950768	hsa-miR-4716-5p	CLIP-seq
MIRT1950769	hsa-miR-4726-3p	CLIP-seq
MIRT1950770	hsa-miR-484	CLIP-seq
MIRT1950771	hsa-miR-509-3-5p	CLIP-seq
MIRT1950772	hsa-miR-509-5p	CLIP-seq
MIRT1950773	hsa-miR-564	CLIP-seq
MIRT1950749	hsa-miR-1184	CLIP-seq
MIRT1950750	hsa-miR-122	CLIP-seq
MIRT2188608	hsa-miR-1227	CLIP-seq
MIRT845370	hsa-miR-1228	CLIP-seq
MIRT2188609	hsa-miR-1245	CLIP-seq
MIRT845371	hsa-miR-1253	CLIP-seq
MIRT2188610	hsa-miR-1262	CLIP-seq
MIRT845372	hsa-miR-128	CLIP-seq
MIRT2188611	hsa-miR-1299	CLIP-seq
MIRT1950751	hsa-miR-1307	CLIP-seq
MIRT845377	hsa-miR-142-5p	CLIP-seq
MIRT845378	hsa-miR-144	CLIP-seq
MIRT1950752	hsa-miR-1915	CLIP-seq
MIRT1950753	hsa-miR-192	CLIP-seq
MIRT1950754	hsa-miR-215	CLIP-seq
MIRT2188612	hsa-miR-23a	CLIP-seq
MIRT2188613	hsa-miR-23b	CLIP-seq
MIRT2188614	hsa-miR-23c	CLIP-seq
MIRT845383	hsa-miR-27a	CLIP-seq
MIRT845384	hsa-miR-27b	CLIP-seq
MIRT845385	hsa-miR-3065-5p	CLIP-seq
MIRT1950755	hsa-miR-3155	CLIP-seq
MIRT1950756	hsa-miR-3155b	CLIP-seq
MIRT2188615	hsa-miR-3161	CLIP-seq
MIRT1950757	hsa-miR-3198	CLIP-seq
MIRT2188616	hsa-miR-3199	CLIP-seq
MIRT2188617	hsa-miR-375	CLIP-seq
MIRT845391	hsa-miR-376a	CLIP-seq
MIRT845392	hsa-miR-376b	CLIP-seq
MIRT845394	hsa-miR-3919	CLIP-seq
MIRT2188618	hsa-miR-3942-3p	CLIP-seq
MIRT2188619	hsa-miR-412	CLIP-seq
MIRT2188620	hsa-miR-421	CLIP-seq
MIRT2188621	hsa-miR-4276	CLIP-seq
MIRT1950762	hsa-miR-4284	CLIP-seq
MIRT2188622	hsa-miR-4302	CLIP-seq
MIRT1950763	hsa-miR-4309	CLIP-seq
MIRT1950764	hsa-miR-4418	CLIP-seq
MIRT1950767	hsa-miR-4638-5p	CLIP-seq
MIRT2188623	hsa-miR-4701-3p	CLIP-seq
MIRT2188624	hsa-miR-4709-5p	CLIP-seq
MIRT2188625	hsa-miR-4715-3p	CLIP-seq
MIRT1950769	hsa-miR-4726-3p	CLIP-seq
MIRT2188626	hsa-miR-4740-5p	CLIP-seq
MIRT845404	hsa-miR-4756-3p	CLIP-seq
MIRT845407	hsa-miR-4793-3p	CLIP-seq
MIRT2188627	hsa-miR-4797-5p	CLIP-seq
MIRT1950770	hsa-miR-484	CLIP-seq
MIRT845409	hsa-miR-500a	CLIP-seq
MIRT845410	hsa-miR-505	CLIP-seq
MIRT845411	hsa-miR-508-5p	CLIP-seq
MIRT1950771	hsa-miR-509-3-5p	CLIP-seq
MIRT1950772	hsa-miR-509-5p	CLIP-seq
MIRT845412	hsa-miR-513a-5p	CLIP-seq
MIRT2188628	hsa-miR-542-3p	CLIP-seq
MIRT2188629	hsa-miR-552	CLIP-seq
MIRT1950773	hsa-miR-564	CLIP-seq
MIRT845413	hsa-miR-580	CLIP-seq
MIRT845417	hsa-miR-610	CLIP-seq
MIRT2188630	hsa-miR-630	CLIP-seq
MIRT845418	hsa-miR-661	CLIP-seq
MIRT2188631	hsa-miR-764	CLIP-seq
MIRT845419	hsa-miR-766	CLIP-seq
MIRT2188609	hsa-miR-1245	CLIP-seq
MIRT1950753	hsa-miR-192	CLIP-seq
MIRT1950754	hsa-miR-215	CLIP-seq
MIRT2385175	hsa-miR-362-5p	CLIP-seq
MIRT1950769	hsa-miR-4726-3p	CLIP-seq
MIRT2385176	hsa-miR-500b	CLIP-seq
MIRT2385177	hsa-miR-502-5p	CLIP-seq
MIRT845372	hsa-miR-128	CLIP-seq
MIRT845377	hsa-miR-142-5p	CLIP-seq
MIRT845378	hsa-miR-144	CLIP-seq
MIRT845383	hsa-miR-27a	CLIP-seq
MIRT845384	hsa-miR-27b	CLIP-seq
MIRT845391	hsa-miR-376a	CLIP-seq
MIRT845392	hsa-miR-376b	CLIP-seq
MIRT845412	hsa-miR-513a-5p	CLIP-seq
MIRT1950750	hsa-miR-122	CLIP-seq
MIRT845371	hsa-miR-1253	CLIP-seq
MIRT1950751	hsa-miR-1307	CLIP-seq
MIRT2492467	hsa-miR-136	CLIP-seq
MIRT1950757	hsa-miR-3198	CLIP-seq
MIRT1950763	hsa-miR-4309	CLIP-seq
MIRT2492468	hsa-miR-4426	CLIP-seq
MIRT1950767	hsa-miR-4638-5p	CLIP-seq
MIRT2492469	hsa-miR-4647	CLIP-seq
MIRT2492470	hsa-miR-4662b	CLIP-seq
MIRT1950769	hsa-miR-4726-3p	CLIP-seq
MIRT845409	hsa-miR-500a	CLIP-seq
MIRT1950773	hsa-miR-564	CLIP-seq
MIRT845413	hsa-miR-580	CLIP-seq
MIRT1950750	hsa-miR-122	CLIP-seq
MIRT2492467	hsa-miR-136	CLIP-seq
MIRT1950757	hsa-miR-3198	CLIP-seq
MIRT1950763	hsa-miR-4309	CLIP-seq
MIRT2492468	hsa-miR-4426	CLIP-seq
MIRT2492469	hsa-miR-4647	CLIP-seq
MIRT2492470	hsa-miR-4662b	CLIP-seq
MIRT1950769	hsa-miR-4726-3p	CLIP-seq
MIRT845409	hsa-miR-500a	CLIP-seq
MIRT1950773	hsa-miR-564	CLIP-seq
MIRT845413	hsa-miR-580	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002528	Process	Regulation of vascular permeability involved in acute inflammatory response	IDA	15527968
GO:0002675	Process	Positive regulation of acute inflammatory response	IDA	15527968
GO:0005634	Component	Nucleus	IDA	15527968
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005730	Component	Nucleolus	IDA
GO:0030155	Process	Regulation of cell adhesion	IDA	15527968

Other IDs

• MIM: 610343
• HGNC: 33627
• e!Ensembl: ENSG00000198535

Protein

• UniProt ID: Q8NCU7
• Protein name: C2 calcium-dependent domain-containing protein 4A (Nuclear-localized factor 1) (Protein FAM148A)
• Protein function: May be involved in inflammatory process. May regulate cell architecture and adhesion.
• Tissue specificity: TISSUE SPECIFICITY: Specifically expressed in endothelial cells. {ECO:0000269|PubMed:15527968}.
• Sequence:

  MWCLERLRLGPECLRRSGDWLLPGRARGAKSRTTAACANVLTPDRIPEFCIPPRLMPRLA
  LAALRNSWVEEAGMDEGAGRTDWDPRSQAALSLPHLPRVRTAYGFCALLESPHTRRKESL
  LLGGPPAPRPRAHTYGGGGGPDALLGTLRVPRAPGPATPAAPGCPRPPQDALARRPRGCR
  LLRVPDGLLSRALRAGRSRRLTRVRSVSSGNEDKERRAGSQSPARAPSTSPPSSRVPFPE
  RLEAEGTVALGRAGDALRLAAEYCPGTGRLRLRLLRAESPAGGAPGPRAVSCRLSLVLRP
  PGTALRQCSTVVGRSRKASFDQDFCFDGLSEDEVRRLAVRVKARDEGRGRERGRLLGQGE
  LSLGALLLL

• Sequence length: 369

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Esophageal atresia	Uncertain significance	rs1596557030	RCV000984720
Pyloric stenosis	Uncertain significance	rs1596557030	RCV000984720

Associations from Text Mining
Disease Name	Relationship Type	References
Autism Spectrum Disorder	Inhibit	37328585
Colonic Neoplasms	Associate	36518255
Diabetes Mellitus Type 2	Associate	21799836, 21873549
Pituitary Neoplasms	Associate	36750863