CSNK1G3 (casein kinase 1 gamma 3)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 1456 |
| Gene name | Casein kinase 1 gamma 3 |
| Gene symbol | CSNK1G3 |
| Synonyms (NCBI Gene) |
CKI-gamma 3CSNK1G3L
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| Chromosome | 5 |
| Chromosome location | 5q23.2 |
| Summary | This gene encodes a member of a family of serine/threonine protein kinases that phosphorylate caseins and other acidic proteins. A related protein in the African clawed frog participates in the transmission of Wnt/beta-catenin signaling. Alternatively spl |
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miRNA
miRNA information provided by mirtarbase database.
531
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9Y6M4 | |||||||||||||||
| Protein name | Casein kinase I isoform gamma-3 (CKI-gamma 3) (EC 2.7.11.1) | |||||||||||||||
| Protein function | Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulat | |||||||||||||||
| PDB | 2CHL , 2IZR , 2IZS , 2IZT , 2IZU , 4G16 , 4G17 , 4HGL , 4HGS , 6GRO | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 447 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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