ARMH4 (armadillo like helical domain containing 4)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
145407
Gene name Gene Name - the full gene name approved by the HGNC.
Armadillo like helical domain containing 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ARMH4
Synonyms (NCBI Gene) Gene synonyms aliases
C14orf37, UT2, c14_5376
Chromosome Chromosome number
14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
14q23.1
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(1)
GO ID Ontology Definition Evidence Reference
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q86TY3
Protein name Armadillo-like helical domain-containing protein 4 (Upstream of mTORC2 protein)
Protein function May modulate immune response and may play a role in inflammation (PubMed:36649229). Down-modulates STAT3 signaling throught direct interaction with IL6ST, resulting in the inhibition of phosphorylation of STAT3 at 'Tyr-705' (PubMed:26927669). Ma
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15767 DUF4696 28 → 610 Domain of unknown function (DUF4696) Family
Tissue specificity TISSUE SPECIFICITY: Expressed in podocytes. {ECO:0000269|PubMed:36649229}.
Sequence
Sequence length 774
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Proteasome-associated autoinflammatory syndrome, digenic PROTEASOME-ASSOCIATED AUTOINFLAMMATORY SYNDROME 1, DIGENIC rs1555353410, rs1555352516, rs748082671
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Myocardial Infarction Myocardial Infarction GWAS
Diabetes Diabetes GWAS