CSN2 (casein beta)

Gene
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1447
Gene name Gene Name - the full gene name approved by the HGNC.
Casein beta
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CSN2
Synonyms (NCBI Gene) Gene synonyms aliases
CASB, PDC213
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q13.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene is a member of the beta casein family. There are two types of casein protein, beta (encoded by this gene) and kappa, both of which are secreted in human milk. Beta casein is the principal protein in human milk and the primary source of essential
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(3)
miRTarBase ID miRNA Experiments Reference
MIRT912029 hsa-miR-3646 CLIP-seq
MIRT912030 hsa-miR-3671 CLIP-seq
MIRT912031 hsa-miR-607 CLIP-seq
Transcription factors
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
Transcription factor Regulation Reference
STAT5A Unknown 15746097;16832345
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(11)
GO ID Ontology Definition Evidence Reference
GO:0004857 Function Enzyme inhibitor activity TAS 2387396
GO:0004869 Function Cysteine-type endopeptidase inhibitor activity IDA 12788072
GO:0005509 Function Calcium ion binding TAS 2387396
GO:0005515 Function Protein binding IPI 31515488, 32296183
GO:0005576 Component Extracellular region TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
115460 2447 ENSG00000135222
Protein
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID P05814
Protein name Beta-casein
Protein function Important role in determination of the surface properties of the casein micelles.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00363 Casein 129 → 210 Casein Family
Tissue specificity TISSUE SPECIFICITY: Mammary gland specific. Secreted in milk.
Sequence 
MKVLILACLVALALARETIESLSSSEESITEYKQKVEKVKHEDQQQGEDEHQDKIYPSFQ
PQPLIYPFVEPIPYGFLPQNILPLAQPAVVLPVPQPEIMEVPKAKDTVYTKGRVMPVLKS
PTIPFFDPQIPKLTDLENLHLPLPLLQPLMQQVPQPIPQTLALPPQPLWSVPQPKVLPIP
QQVVPYPQRAVPVQALLLNQELLLNPTHQIYPVTQPLAPVHNPISV
Sequence length 226
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG   Reactome
  Prolactin signaling pathway   Nuclear signaling by ERBB4
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Carcinoma Carcinoma, Carcinoma, Spindle-Cell, Undifferentiated carcinoma rs121912654, rs555607708, rs786202962, rs1564055259 16316942, 9879772
Show/Hide Text Mining Associations (2)
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 15534001
Leukemia Myeloid Acute Associate 8634413