C12orf60 (chromosome 12 open reading frame 60)

Gene

• Entrez ID: 144608
• Gene name: Chromosome 12 open reading frame 60
• Gene symbol: C12orf60
• Synonyms (NCBI Gene): -
• Chromosome: 12
• Chromosome location: 12p12.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018604	hsa-miR-335-5p	Microarray	18185580
MIRT608948	hsa-miR-511-3p	HITS-CLIP	24906430
MIRT608946	hsa-miR-567	HITS-CLIP	24906430
MIRT608947	hsa-miR-223-5p	HITS-CLIP	24906430
MIRT608945	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT608944	hsa-miR-297	HITS-CLIP	24906430
MIRT608943	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT608947	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT608947	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT608944	hsa-miR-297	HITS-CLIP	27418678
MIRT608944	hsa-miR-297	HITS-CLIP	27418678
MIRT608948	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT608948	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT608946	hsa-miR-567	HITS-CLIP	27418678
MIRT608946	hsa-miR-567	HITS-CLIP	27418678
MIRT608943	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608943	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608943	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608945	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608945	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608945	hsa-miR-6867-5p	HITS-CLIP	27418678

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5U649
• Protein name: Uncharacterized protein C12orf60
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15047	DUF4533	8 → 233	Protein of unknown function (DUF4533)	Family

• Sequence:

  MSSESEKDKERLIQAAKMFFFHVQDLASVINTLTELFSRSMNTQILLMAVKNNSYIKDFF
  EQMLKIFKEMQSVVDARHDKIQKESLCSKVAMAMCSVVQKSTNVEELHQSAKEVFKSAHT
  PVIISVLNSSNILGSLESSLSHLMKFPIMNLQLSDFYTEDTKEQSDVTTSERTRSPPGSS
  KTTMIDTLKKLQDVLKTEDSKNPTKSAADLLEQIVKAMGPILEILQKAIKTMEMNISVFK
  KASDK

• Sequence length: 245

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
OSTEOARTHRITIS, HAND	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HIP	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, KNEE	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations