Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	144402
Gene name Gene Name - the full gene name approved by the HGNC.	Copine 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CPNE8
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q12
Summary Summary of gene provided in NCBI Entrez Gene.	Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an in

Show/Hide all(119)

miRTarBase ID	miRNA	Experiments	Reference
MIRT005134	hsa-miR-30a-5p	pSILAC	18668040
MIRT022217	hsa-miR-124-3p	Microarray	18668037
MIRT005134	hsa-miR-30a-5p	Proteomics;Other	18668040
MIRT051072	hsa-miR-16-5p	CLASH	23622248
MIRT704491	hsa-miR-8485	HITS-CLIP	23313552
MIRT704492	hsa-miR-4719	HITS-CLIP	23313552
MIRT704491	hsa-miR-8485	HITS-CLIP	23313552
MIRT704492	hsa-miR-4719	HITS-CLIP	23313552
MIRT906762	hsa-miR-224	CLIP-seq
MIRT906763	hsa-miR-30a	CLIP-seq
MIRT906764	hsa-miR-30b	CLIP-seq
MIRT906765	hsa-miR-30c	CLIP-seq
MIRT906766	hsa-miR-30d	CLIP-seq
MIRT906767	hsa-miR-30e	CLIP-seq
MIRT906768	hsa-miR-3148	CLIP-seq
MIRT906769	hsa-miR-3163	CLIP-seq
MIRT906770	hsa-miR-340	CLIP-seq
MIRT906771	hsa-miR-3620	CLIP-seq
MIRT906772	hsa-miR-4251	CLIP-seq
MIRT906773	hsa-miR-4477a	CLIP-seq
MIRT906774	hsa-miR-4495	CLIP-seq
MIRT906775	hsa-miR-4503	CLIP-seq
MIRT906776	hsa-miR-539	CLIP-seq
MIRT906777	hsa-miR-548ac	CLIP-seq
MIRT906778	hsa-miR-548d-3p	CLIP-seq
MIRT906779	hsa-miR-548n	CLIP-seq
MIRT906780	hsa-miR-548t	CLIP-seq
MIRT906781	hsa-miR-548z	CLIP-seq
MIRT906782	hsa-miR-802	CLIP-seq
MIRT906783	hsa-miR-944	CLIP-seq
MIRT906769	hsa-miR-3163	CLIP-seq
MIRT906770	hsa-miR-340	CLIP-seq
MIRT1968719	hsa-miR-3653	CLIP-seq
MIRT1968720	hsa-miR-3658	CLIP-seq
MIRT1968721	hsa-miR-4511	CLIP-seq
MIRT1968722	hsa-miR-4773	CLIP-seq
MIRT1968723	hsa-miR-548b-3p	CLIP-seq
MIRT1968724	hsa-miR-642b	CLIP-seq
MIRT2386418	hsa-miR-188-5p	CLIP-seq
MIRT2386419	hsa-miR-204	CLIP-seq
MIRT2386420	hsa-miR-211	CLIP-seq
MIRT2386421	hsa-miR-335	CLIP-seq
MIRT2386422	hsa-miR-4676-5p	CLIP-seq
MIRT2386423	hsa-miR-575	CLIP-seq
MIRT2447529	hsa-miR-3145-3p	CLIP-seq
MIRT2447530	hsa-miR-513a-3p	CLIP-seq
MIRT2508178	hsa-miR-1302	CLIP-seq
MIRT2508179	hsa-miR-1324	CLIP-seq
MIRT2508180	hsa-miR-137	CLIP-seq
MIRT2508181	hsa-miR-145	CLIP-seq
MIRT2508182	hsa-miR-190	CLIP-seq
MIRT2508183	hsa-miR-190b	CLIP-seq
MIRT2508184	hsa-miR-198	CLIP-seq
MIRT2386419	hsa-miR-204	CLIP-seq
MIRT2386420	hsa-miR-211	CLIP-seq
MIRT906762	hsa-miR-224	CLIP-seq
MIRT2508185	hsa-miR-2355-3p	CLIP-seq
MIRT2508186	hsa-miR-25	CLIP-seq
MIRT2508187	hsa-miR-299-3p	CLIP-seq
MIRT2508188	hsa-miR-3121-3p	CLIP-seq
MIRT2508189	hsa-miR-3122	CLIP-seq
MIRT2508190	hsa-miR-3124-3p	CLIP-seq
MIRT906769	hsa-miR-3163	CLIP-seq
MIRT2508191	hsa-miR-3171	CLIP-seq
MIRT2508192	hsa-miR-3180-5p	CLIP-seq
MIRT2508193	hsa-miR-32	CLIP-seq
MIRT906770	hsa-miR-340	CLIP-seq
MIRT906771	hsa-miR-3620	CLIP-seq
MIRT2508194	hsa-miR-363	CLIP-seq
MIRT2508195	hsa-miR-367	CLIP-seq
MIRT2508196	hsa-miR-3691-5p	CLIP-seq
MIRT2508197	hsa-miR-3913-5p	CLIP-seq
MIRT2508198	hsa-miR-4298	CLIP-seq
MIRT2508199	hsa-miR-4311	CLIP-seq
MIRT2508200	hsa-miR-4422	CLIP-seq
MIRT2508201	hsa-miR-4446-5p	CLIP-seq
MIRT2508202	hsa-miR-4491	CLIP-seq
MIRT2508203	hsa-miR-450b-5p	CLIP-seq
MIRT2508204	hsa-miR-452	CLIP-seq
MIRT2508205	hsa-miR-4646-3p	CLIP-seq
MIRT2508206	hsa-miR-4652-3p	CLIP-seq
MIRT2508207	hsa-miR-4657	CLIP-seq
MIRT2508208	hsa-miR-4676-3p	CLIP-seq
MIRT2508209	hsa-miR-4712-5p	CLIP-seq
MIRT2508210	hsa-miR-4729	CLIP-seq
MIRT2508211	hsa-miR-4752	CLIP-seq
MIRT2508212	hsa-miR-4755-5p	CLIP-seq
MIRT2508213	hsa-miR-4764-5p	CLIP-seq
MIRT906779	hsa-miR-548n	CLIP-seq
MIRT906780	hsa-miR-548t	CLIP-seq
MIRT2508214	hsa-miR-570	CLIP-seq
MIRT2508215	hsa-miR-581	CLIP-seq
MIRT2508216	hsa-miR-623	CLIP-seq
MIRT2508217	hsa-miR-770-5p	CLIP-seq
MIRT2508218	hsa-miR-92a	CLIP-seq
MIRT2508219	hsa-miR-92b	CLIP-seq
MIRT2508179	hsa-miR-1324	CLIP-seq
MIRT2508180	hsa-miR-137	CLIP-seq
MIRT2508184	hsa-miR-198	CLIP-seq
MIRT2386419	hsa-miR-204	CLIP-seq
MIRT2386420	hsa-miR-211	CLIP-seq
MIRT2508185	hsa-miR-2355-3p	CLIP-seq
MIRT2508186	hsa-miR-25	CLIP-seq
MIRT2508188	hsa-miR-3121-3p	CLIP-seq
MIRT2508193	hsa-miR-32	CLIP-seq
MIRT2508194	hsa-miR-363	CLIP-seq
MIRT2508195	hsa-miR-367	CLIP-seq
MIRT2508199	hsa-miR-4311	CLIP-seq
MIRT2508200	hsa-miR-4422	CLIP-seq
MIRT2508201	hsa-miR-4446-5p	CLIP-seq
MIRT2508203	hsa-miR-450b-5p	CLIP-seq
MIRT2508205	hsa-miR-4646-3p	CLIP-seq
MIRT2508206	hsa-miR-4652-3p	CLIP-seq
MIRT2508210	hsa-miR-4729	CLIP-seq
MIRT2508212	hsa-miR-4755-5p	CLIP-seq
MIRT2508215	hsa-miR-581	CLIP-seq
MIRT2508216	hsa-miR-623	CLIP-seq
MIRT2508218	hsa-miR-92a	CLIP-seq
MIRT2508219	hsa-miR-92b	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005544	Function	Calcium-dependent phospholipid binding	IBA	21873635
GO:0005886	Component	Plasma membrane	IBA	21873635
GO:0008150	Process	Biological_process	ND
GO:0046872	Function	Metal ion binding	IEA
GO:0070062	Component	Extracellular exosome	HDA	20458337, 23533145
GO:0071277	Process	Cellular response to calcium ion	IBA	21873635

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q86YQ8

Protein name

Copine-8 (Copine VIII)

Protein function

Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00168	C2	25 → 135	C2 domain	Domain
PF00168	C2	159 → 267	C2 domain	Domain
PF07002	Copine	328 → 547	Copine	Family

Sequence

MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEW
REFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTL
GEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDP
FLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDG
SHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLD
YIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMF
PALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVIN
HVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMV
ELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMR
ARGIKPSPAPPPYTPPTHVLQTQI

Sequence length

564

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Disease term	Disease name	Source
Unknown
Irritable Bowel Syndrome	Irritable Bowel Syndrome	GWAS
Bipolar Disorder	Bipolar Disorder	GWAS
Metabolic Syndrome	Metabolic Syndrome	GWAS
Diabetes	Diabetes	GWAS

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	27081041
Carcinoma Renal Cell	Associate	31487856
Lymphoma Non Hodgkin	Associate	31487856
Multiple Myeloma	Associate	33780365
Neoplasm Metastasis	Stimulate	35982908
Neoplasms	Associate	35982908
Squamous Cell Carcinoma of Head and Neck	Associate	35409173
Stomach Neoplasms	Associate	34663825, 35982908

CPNE8 (copine 8)