Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
144245
Gene name Gene Name - the full gene name approved by the HGNC.
ALG10 alpha-1,2-glucosyltransferase B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ALG10B
Synonyms (NCBI Gene) Gene synonyms aliases
ALG10, KCR1
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT026560 hsa-miR-192-5p Microarray 19074876
MIRT050088 hsa-miR-26a-5p CLASH 23622248
MIRT695049 hsa-miR-6808-5p HITS-CLIP 23313552
MIRT695048 hsa-miR-6893-5p HITS-CLIP 23313552
MIRT695047 hsa-miR-940 HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005783 Component Endoplasmic reticulum IBA 21873635
GO:0005783 Component Endoplasmic reticulum IDA 14525949
GO:0005886 Component Plasma membrane IEA
GO:0006486 Process Protein glycosylation IMP 14525949
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603313 31088 ENSG00000175548
Protein
UniProt ID Q5I7T1
Protein name Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase (EC 2.4.1.256) (Alpha-1,2-glucosyltransferase ALG10-A) (Alpha-2-glucosyltransferase ALG10-B) (Asparagine-linked glycosylation protein 10 homolog B) (Potassium channel regulator 1)
Protein function Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase that operates in the biosynthetic pathway of dolichol-linked oligosaccharides, the glycan precursors employed in protein asparagine (N)-glycosylation. The assembly of dolichol-
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04922 DIE2_ALG10 31 427 DIE2/ALG10 family Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in heart, placenta, liver, kidney and pancreas. Weakly expressed in lung, skeletal muscle and brain. {ECO:0000269|PubMed:14525949}.
Sequence
Sequence length 473
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  N-Glycan biosynthesis
Metabolic pathways
 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Long qt syndrome Long Qt Syndrome 2 rs121434386, rs120074177, rs104894252, rs120074181, rs120074182, rs120074178, rs120074179, rs120074180, rs12720459, rs120074183, rs120074184, rs120074185, rs120074186, rs17215500, rs120074188
View all (552 more)
Ventricular fibrillation Ventricular Fibrillation rs137854604, rs587782933, rs190140598
Unknown
Disease term Disease name Evidence References Source
Torsades de pointes Torsades de Pointes ClinVar
Long QT Syndrome long QT syndrome 2 GenCC
Diabetes Diabetes GWAS
Associations from Text Mining
Disease Name Relationship Type References
Long QT Syndrome Associate 37071726
Long Qt Syndrome 2 Associate 37071726