SPTY2D1 (SPT2 chromatin protein domain containing 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 144108 |
| Gene name | SPT2 chromatin protein domain containing 1 |
| Gene symbol | SPTY2D1 |
| Synonyms (NCBI Gene) |
Spt2
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| Chromosome | 11 |
| Chromosome location | 11p15.1 |
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miRNA
miRNA information provided by mirtarbase database.
764
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q68D10 | ||||||||||
| Protein name | Protein SPT2 homolog (Protein KU002155) (SPT2 domain-containing protein 1) | ||||||||||
| Protein function | Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). Required for normal chromatin refolding in the coding region of transcribed genes, and for th | ||||||||||
| PDB | 5BS7 , 5BSA | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 685 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
7
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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