POGLUT3 (protein O-glucosyltransferase 3)

Gene

• Entrez ID: 143888
• Gene name: Protein O-glucosyltransferase 3
• Gene symbol: POGLUT3
• Synonyms (NCBI Gene): KDELC2
• Chromosome: 11
• Chromosome location: 11q22.3

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005788	Component	Endoplasmic reticulum lumen	IEA
GO:0006486	Process	Protein glycosylation	IEA
GO:0012505	Component	Endomembrane system	IBA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0035251	Function	UDP-glucosyltransferase activity	IDA	30127001
GO:0035251	Function	UDP-glucosyltransferase activity	IEA
GO:0035252	Function	UDP-xylosyltransferase activity	IDA	30127001
GO:0035252	Function	UDP-xylosyltransferase activity	IEA
GO:0046527	Function	Glucosyltransferase activity	IBA
GO:0140561	Function	EGF-domain serine glucosyltransferase activity	IEA
GO:0140562	Function	EGF-domain serine xylosyltransferase activity	IEA

Other IDs

• MIM: 618503
• HGNC: 28496
• e!Ensembl: ENSG00000178202

Protein

• UniProt ID: Q7Z4H8
• Protein name: Protein O-glucosyltransferase 3 (EC 2.4.1.-) (KDEL motif-containing protein 2) (Protein O-xylosyltransferase POGLUT3) (EC 2.4.2.-)
• Protein function: Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed:30127001). Can also catalyze the transfer of xylose from UDP-xylose but les
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00630	Filamin	26 → 131	Filamin/ABP280 repeat	Domain
  PF05686	Glyco_transf_90	151 → 505	Glycosyl transferase family 90	Family

• Sequence:

  MRRLPRALLLQLRLALLVAAGAPEVLVSAPRSLVWGPGLQAAVVLPVRYFYLQAVNSEGQ
  NLTRSPAGETPFKVVVKSLSPKELVRIHVPKPLDRNDGTFLMRYRMYETVDEGLKIEVLY
  GDEHVAQSPYILKGPVYHEYCECPEDPQAWQKTLSCPTKEPQIAKDFASFPSINLQQMLK
  EVPKRFGDERGAIVHYTILNNHVYRRSLGKYTDFKMFSDEILLSLTRKVLLPDLEFYVNL
  GDWPLEHRKVNGTPSPIPIISWCGSLDSRDVVLPTYDITHSMLEAMRGVTNDLLSIQGNT
  GPSWINKTERAFFRGRDSREERLQLVQLSKENPQLLDAGITGYFFFQEKEKELGKAKLMG
  FFDFFKYKYQVNVDGTVAAYRYPYLMLGDSLVLKQDSPYYEHFYMALEPWKHYVPIKRNL
  SDLLEKVKWAKENDEEAKKIAKEGQLMARDLLQPHRLYCYYYQVLQKYAERQSSKPEVRD
  GMELVPQPEDSTAICQCHRKKPSREEL

• Sequence length: 507