MPP7 (MAGUK p55 scaffold protein 7)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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143098 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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MAGUK p55 scaffold protein 7 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MPP7 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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10 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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10p12.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||
| UniProt ID | Q5T2T1 | ||||||||||||||||||||||||||||||
| Protein name | MAGUK p55 subfamily member 7 | ||||||||||||||||||||||||||||||
| Protein function | Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. | ||||||||||||||||||||||||||||||
| PDB | 3LRA , 3O46 | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 576 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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