MPP7 (MAGUK p55 scaffold protein 7)

Gene

• Entrez ID: 143098
• Gene name: MAGUK p55 scaffold protein 7
• Gene symbol: MPP7
• Synonyms (NCBI Gene): -
• Chromosome: 10
• Chromosome location: 10p12.1
• Summary: The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT028259	hsa-miR-32-5p	Sequencing	20371350
MIRT1156495	hsa-miR-10a	CLIP-seq
MIRT1156496	hsa-miR-10b	CLIP-seq
MIRT1156497	hsa-miR-1179	CLIP-seq
MIRT1156498	hsa-miR-122	CLIP-seq
MIRT1156499	hsa-miR-1253	CLIP-seq
MIRT1156500	hsa-miR-1264	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156502	hsa-miR-1285	CLIP-seq
MIRT1156503	hsa-miR-1287	CLIP-seq
MIRT1156504	hsa-miR-134	CLIP-seq
MIRT1156505	hsa-miR-140-5p	CLIP-seq
MIRT1156506	hsa-miR-154	CLIP-seq
MIRT1156507	hsa-miR-23a	CLIP-seq
MIRT1156508	hsa-miR-23b	CLIP-seq
MIRT1156509	hsa-miR-23c	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156511	hsa-miR-3118	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156513	hsa-miR-3135b	CLIP-seq
MIRT1156514	hsa-miR-3164	CLIP-seq
MIRT1156515	hsa-miR-3165	CLIP-seq
MIRT1156516	hsa-miR-3173-3p	CLIP-seq
MIRT1156517	hsa-miR-3187-5p	CLIP-seq
MIRT1156518	hsa-miR-3198	CLIP-seq
MIRT1156519	hsa-miR-339-5p	CLIP-seq
MIRT1156520	hsa-miR-3613-3p	CLIP-seq
MIRT1156521	hsa-miR-3650	CLIP-seq
MIRT1156522	hsa-miR-3653	CLIP-seq
MIRT1156523	hsa-miR-3658	CLIP-seq
MIRT1156524	hsa-miR-3662	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156529	hsa-miR-371-5p	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156533	hsa-miR-3922-5p	CLIP-seq
MIRT1156534	hsa-miR-4251	CLIP-seq
MIRT1156535	hsa-miR-4279	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156537	hsa-miR-4307	CLIP-seq
MIRT1156538	hsa-miR-4309	CLIP-seq
MIRT1156539	hsa-miR-4329	CLIP-seq
MIRT1156540	hsa-miR-4421	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT1156542	hsa-miR-4434	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT1156545	hsa-miR-4505	CLIP-seq
MIRT1156546	hsa-miR-4516	CLIP-seq
MIRT1156547	hsa-miR-4517	CLIP-seq
MIRT1156548	hsa-miR-4531	CLIP-seq
MIRT1156549	hsa-miR-4695-5p	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT1156551	hsa-miR-4717-3p	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156553	hsa-miR-4725-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156555	hsa-miR-4753-5p	CLIP-seq
MIRT1156556	hsa-miR-502-5p	CLIP-seq
MIRT1156557	hsa-miR-504	CLIP-seq
MIRT1156558	hsa-miR-5096	CLIP-seq
MIRT1156559	hsa-miR-564	CLIP-seq
MIRT1156560	hsa-miR-576-5p	CLIP-seq
MIRT1156561	hsa-miR-592	CLIP-seq
MIRT1156562	hsa-miR-593	CLIP-seq
MIRT1156563	hsa-miR-597	CLIP-seq
MIRT1156564	hsa-miR-603	CLIP-seq
MIRT1156565	hsa-miR-612	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT1156567	hsa-miR-935	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156569	hsa-miR-944	CLIP-seq
MIRT1156497	hsa-miR-1179	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156499	hsa-miR-1253	CLIP-seq
MIRT1156500	hsa-miR-1264	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT2044799	hsa-miR-139-5p	CLIP-seq
MIRT1156506	hsa-miR-154	CLIP-seq
MIRT2044800	hsa-miR-181a	CLIP-seq
MIRT2044801	hsa-miR-181b	CLIP-seq
MIRT2044802	hsa-miR-181c	CLIP-seq
MIRT2044803	hsa-miR-181d	CLIP-seq
MIRT2044804	hsa-miR-217	CLIP-seq
MIRT2044805	hsa-miR-223	CLIP-seq
MIRT2044806	hsa-miR-298	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT2044807	hsa-miR-3127-5p	CLIP-seq
MIRT2044808	hsa-miR-3201	CLIP-seq
MIRT2044809	hsa-miR-340	CLIP-seq
MIRT2044810	hsa-miR-3671	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT2044811	hsa-miR-3941	CLIP-seq
MIRT2044812	hsa-miR-3974	CLIP-seq
MIRT1156534	hsa-miR-4251	CLIP-seq
MIRT2044813	hsa-miR-4262	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156537	hsa-miR-4307	CLIP-seq
MIRT2044814	hsa-miR-4328	CLIP-seq
MIRT1156539	hsa-miR-4329	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT2044815	hsa-miR-4476	CLIP-seq
MIRT1156547	hsa-miR-4517	CLIP-seq
MIRT2044816	hsa-miR-4530	CLIP-seq
MIRT2044817	hsa-miR-4539	CLIP-seq
MIRT2044818	hsa-miR-466	CLIP-seq
MIRT2044819	hsa-miR-4666-5p	CLIP-seq
MIRT2044820	hsa-miR-4668-3p	CLIP-seq
MIRT2044821	hsa-miR-4672	CLIP-seq
MIRT2044822	hsa-miR-4680-5p	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT2044823	hsa-miR-4697-3p	CLIP-seq
MIRT2044824	hsa-miR-4699-3p	CLIP-seq
MIRT2044825	hsa-miR-4705	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT2044826	hsa-miR-4731-3p	CLIP-seq
MIRT2044827	hsa-miR-4786-5p	CLIP-seq
MIRT2044828	hsa-miR-4791	CLIP-seq
MIRT2044829	hsa-miR-4801	CLIP-seq
MIRT2044830	hsa-miR-493	CLIP-seq
MIRT2044831	hsa-miR-513c	CLIP-seq
MIRT2044832	hsa-miR-514b-5p	CLIP-seq
MIRT2044833	hsa-miR-518e	CLIP-seq
MIRT2044834	hsa-miR-548c-3p	CLIP-seq
MIRT2044835	hsa-miR-590-3p	CLIP-seq
MIRT2044836	hsa-miR-607	CLIP-seq
MIRT2044837	hsa-miR-634	CLIP-seq
MIRT2044838	hsa-miR-656	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT2044839	hsa-miR-769-5p	CLIP-seq
MIRT2044840	hsa-miR-888	CLIP-seq
MIRT2044841	hsa-miR-922	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156569	hsa-miR-944	CLIP-seq
MIRT1156497	hsa-miR-1179	CLIP-seq
MIRT2274014	hsa-miR-1207-5p	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT2274015	hsa-miR-1297	CLIP-seq
MIRT2274016	hsa-miR-1305	CLIP-seq
MIRT2044799	hsa-miR-139-5p	CLIP-seq
MIRT2044800	hsa-miR-181a	CLIP-seq
MIRT2044801	hsa-miR-181b	CLIP-seq
MIRT2044802	hsa-miR-181c	CLIP-seq
MIRT2044803	hsa-miR-181d	CLIP-seq
MIRT2274017	hsa-miR-199a-3p	CLIP-seq
MIRT2274018	hsa-miR-199b-3p	CLIP-seq
MIRT2044804	hsa-miR-217	CLIP-seq
MIRT2044805	hsa-miR-223	CLIP-seq
MIRT2274019	hsa-miR-26a	CLIP-seq
MIRT2274020	hsa-miR-26b	CLIP-seq
MIRT2274021	hsa-miR-3064-3p	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT2274022	hsa-miR-3129-5p	CLIP-seq
MIRT2274023	hsa-miR-3158-3p	CLIP-seq
MIRT1156514	hsa-miR-3164	CLIP-seq
MIRT1156515	hsa-miR-3165	CLIP-seq
MIRT2044808	hsa-miR-3201	CLIP-seq
MIRT2274024	hsa-miR-3614-5p	CLIP-seq
MIRT2274025	hsa-miR-3647-3p	CLIP-seq
MIRT2274026	hsa-miR-3660	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT2044810	hsa-miR-3671	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT2274027	hsa-miR-378	CLIP-seq
MIRT2274028	hsa-miR-378b	CLIP-seq
MIRT2274029	hsa-miR-378c	CLIP-seq
MIRT2274030	hsa-miR-378d	CLIP-seq
MIRT2274031	hsa-miR-378e	CLIP-seq
MIRT2274032	hsa-miR-378f	CLIP-seq
MIRT2274033	hsa-miR-378h	CLIP-seq
MIRT2274034	hsa-miR-378i	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT2044811	hsa-miR-3941	CLIP-seq
MIRT2274035	hsa-miR-409-3p	CLIP-seq
MIRT2274036	hsa-miR-422a	CLIP-seq
MIRT2044813	hsa-miR-4262	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156537	hsa-miR-4307	CLIP-seq
MIRT2044814	hsa-miR-4328	CLIP-seq
MIRT2274037	hsa-miR-4420	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT2274038	hsa-miR-4457	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT2274039	hsa-miR-4465	CLIP-seq
MIRT2274040	hsa-miR-4520a-3p	CLIP-seq
MIRT2274041	hsa-miR-4526	CLIP-seq
MIRT2274042	hsa-miR-4638-3p	CLIP-seq
MIRT2044818	hsa-miR-466	CLIP-seq
MIRT2044819	hsa-miR-4666-5p	CLIP-seq
MIRT2044821	hsa-miR-4672	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT2044824	hsa-miR-4699-3p	CLIP-seq
MIRT2044825	hsa-miR-4705	CLIP-seq
MIRT2274043	hsa-miR-4715-3p	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT2044826	hsa-miR-4731-3p	CLIP-seq
MIRT1156555	hsa-miR-4753-5p	CLIP-seq
MIRT2274044	hsa-miR-4760-5p	CLIP-seq
MIRT2274045	hsa-miR-4763-3p	CLIP-seq
MIRT2044828	hsa-miR-4791	CLIP-seq
MIRT2044829	hsa-miR-4801	CLIP-seq
MIRT2274046	hsa-miR-498	CLIP-seq
MIRT1156558	hsa-miR-5096	CLIP-seq
MIRT2274047	hsa-miR-513a-3p	CLIP-seq
MIRT2044831	hsa-miR-513c	CLIP-seq
MIRT2044832	hsa-miR-514b-5p	CLIP-seq
MIRT2274048	hsa-miR-550b	CLIP-seq
MIRT2274049	hsa-miR-556-3p	CLIP-seq
MIRT1156559	hsa-miR-564	CLIP-seq
MIRT2274050	hsa-miR-578	CLIP-seq
MIRT2274051	hsa-miR-582-5p	CLIP-seq
MIRT2044835	hsa-miR-590-3p	CLIP-seq
MIRT2044836	hsa-miR-607	CLIP-seq
MIRT2274052	hsa-miR-628-5p	CLIP-seq
MIRT2044838	hsa-miR-656	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT2044840	hsa-miR-888	CLIP-seq
MIRT2274053	hsa-miR-936	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156569	hsa-miR-944	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT2431261	hsa-miR-3618	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT2431261	hsa-miR-3618	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT2442387	hsa-miR-1251	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156495	hsa-miR-10a	CLIP-seq
MIRT1156496	hsa-miR-10b	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156519	hsa-miR-339-5p	CLIP-seq
MIRT1156520	hsa-miR-3613-3p	CLIP-seq
MIRT2431261	hsa-miR-3618	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT2572867	hsa-miR-3679-3p	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156529	hsa-miR-371-5p	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156531	hsa-miR-380	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156536	hsa-miR-4293	CLIP-seq
MIRT1156540	hsa-miR-4421	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT2572868	hsa-miR-4446-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156544	hsa-miR-4495	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156553	hsa-miR-4725-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156557	hsa-miR-504	CLIP-seq
MIRT2572869	hsa-miR-548l	CLIP-seq
MIRT2572870	hsa-miR-548n	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq
MIRT1156495	hsa-miR-10a	CLIP-seq
MIRT1156496	hsa-miR-10b	CLIP-seq
MIRT2044797	hsa-miR-1225-3p	CLIP-seq
MIRT2044798	hsa-miR-1233	CLIP-seq
MIRT1156501	hsa-miR-1273e	CLIP-seq
MIRT1156510	hsa-miR-31	CLIP-seq
MIRT1156512	hsa-miR-3122	CLIP-seq
MIRT1156519	hsa-miR-339-5p	CLIP-seq
MIRT1156520	hsa-miR-3613-3p	CLIP-seq
MIRT1156525	hsa-miR-3667-5p	CLIP-seq
MIRT2572867	hsa-miR-3679-3p	CLIP-seq
MIRT1156526	hsa-miR-3689a-3p	CLIP-seq
MIRT1156527	hsa-miR-3689c	CLIP-seq
MIRT1156528	hsa-miR-3714	CLIP-seq
MIRT1156529	hsa-miR-371-5p	CLIP-seq
MIRT1156530	hsa-miR-371b-5p	CLIP-seq
MIRT1156532	hsa-miR-3913-5p	CLIP-seq
MIRT1156540	hsa-miR-4421	CLIP-seq
MIRT1156541	hsa-miR-4433	CLIP-seq
MIRT2572868	hsa-miR-4446-5p	CLIP-seq
MIRT1156543	hsa-miR-4459	CLIP-seq
MIRT1156550	hsa-miR-4696	CLIP-seq
MIRT1156552	hsa-miR-4722-5p	CLIP-seq
MIRT1156553	hsa-miR-4725-5p	CLIP-seq
MIRT1156554	hsa-miR-4728-5p	CLIP-seq
MIRT1156557	hsa-miR-504	CLIP-seq
MIRT1156566	hsa-miR-665	CLIP-seq
MIRT1156568	hsa-miR-940	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	17237226, 24366813, 28514442, 32296183, 33961781
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005911	Component	Cell-cell junction	IBA
GO:0005912	Component	Adherens junction	IDA	17237226
GO:0005912	Component	Adherens junction	IEA
GO:0005923	Component	Bicellular tight junction	IDA	17332497
GO:0005923	Component	Bicellular tight junction	IEA
GO:0005938	Component	Cell cortex	IEA
GO:0016020	Component	Membrane	IEA
GO:0016328	Component	Lateral plasma membrane	IEA
GO:0019904	Function	Protein domain specific binding	IPI	17332497
GO:0030010	Process	Establishment of cell polarity	TAS	17332497
GO:0030054	Component	Cell junction	IDA
GO:0031334	Process	Positive regulation of protein-containing complex assembly	IDA	17237226
GO:0031334	Process	Positive regulation of protein-containing complex assembly	TAS	14719143
GO:0035591	Function	Signaling adaptor activity	NAS	14719143
GO:0035591	Function	Signaling adaptor activity	TAS	20702775
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0060090	Function	Molecular adaptor activity	IDA	17237226, 20702775
GO:0070161	Component	Anchoring junction	IEA
GO:0070830	Process	Bicellular tight junction assembly	IDA	17332497
GO:0071896	Process	Protein localization to adherens junction	IBA
GO:0071896	Process	Protein localization to adherens junction	IMP	17237226
GO:0097025	Component	MPP7-DLG1-LIN7 complex	IDA	17237226, 20702775

Other IDs

• MIM: 610973
• HGNC: 26542
• e!Ensembl: ENSG00000150054

Protein

• UniProt ID: Q5T2T1
• Protein name: MAGUK p55 subfamily member 7
• Protein function: Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
• PDB: 3LRA, 3O46
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02828	L27	15 → 67	L27 domain	Domain
  PF02828	L27	73 → 124	L27 domain	Domain
  PF00595	PDZ	139 → 217	PDZ domain	Domain
  PF00018	SH3_1	234 → 290	SH3 domain	Domain
  PF00625	Guanylate_kin	367 → 562	Guanylate kinase	Domain

• Sequence:

  MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYY
  EKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYD
  PVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIH
  VGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYN
  PNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLAL
  RRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPY
  RRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFI
  SKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFK
  PYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFD
  KIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS

• Sequence length: 576