Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	140767
Gene name Gene Name - the full gene name approved by the HGNC.	Neurensin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NRSN1
Synonyms (NCBI Gene) Gene synonyms aliases	VMP, p24
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6p22.3

Show/Hide all(123)

miRTarBase ID	miRNA	Experiments
MIRT1194439	hsa-miR-1207-5p	CLIP-seq
MIRT1194440	hsa-miR-1225-3p	CLIP-seq
MIRT1194441	hsa-miR-1233	CLIP-seq
MIRT1194442	hsa-miR-1252	CLIP-seq
MIRT1194443	hsa-miR-196a	CLIP-seq
MIRT1194444	hsa-miR-196b	CLIP-seq
MIRT1194445	hsa-miR-2114	CLIP-seq
MIRT1194446	hsa-miR-3154	CLIP-seq
MIRT1194447	hsa-miR-3665	CLIP-seq
MIRT1194448	hsa-miR-3689a-3p	CLIP-seq
MIRT1194449	hsa-miR-3689c	CLIP-seq
MIRT1194450	hsa-miR-377	CLIP-seq
MIRT1194451	hsa-miR-3922-5p	CLIP-seq
MIRT1194452	hsa-miR-3929	CLIP-seq
MIRT1194453	hsa-miR-411	CLIP-seq
MIRT1194454	hsa-miR-4419b	CLIP-seq
MIRT1194455	hsa-miR-4433	CLIP-seq
MIRT1194456	hsa-miR-4478	CLIP-seq
MIRT1194457	hsa-miR-4728-5p	CLIP-seq
MIRT1194458	hsa-miR-4736	CLIP-seq
MIRT1194459	hsa-miR-4762-5p	CLIP-seq
MIRT1194460	hsa-miR-4763-3p	CLIP-seq
MIRT1194461	hsa-miR-4778-3p	CLIP-seq
MIRT1194462	hsa-miR-485-5p	CLIP-seq
MIRT1194463	hsa-miR-550a	CLIP-seq
MIRT1194464	hsa-miR-665	CLIP-seq
MIRT1194465	hsa-miR-764	CLIP-seq
MIRT1194466	hsa-miR-890	CLIP-seq
MIRT1194439	hsa-miR-1207-5p	CLIP-seq
MIRT1194440	hsa-miR-1225-3p	CLIP-seq
MIRT1194441	hsa-miR-1233	CLIP-seq
MIRT1194442	hsa-miR-1252	CLIP-seq
MIRT2056507	hsa-miR-1293	CLIP-seq
MIRT1194445	hsa-miR-2114	CLIP-seq
MIRT1194447	hsa-miR-3665	CLIP-seq
MIRT1194448	hsa-miR-3689a-3p	CLIP-seq
MIRT1194449	hsa-miR-3689c	CLIP-seq
MIRT1194451	hsa-miR-3922-5p	CLIP-seq
MIRT1194452	hsa-miR-3929	CLIP-seq
MIRT1194454	hsa-miR-4419b	CLIP-seq
MIRT1194455	hsa-miR-4433	CLIP-seq
MIRT1194456	hsa-miR-4478	CLIP-seq
MIRT2056508	hsa-miR-4483	CLIP-seq
MIRT2056509	hsa-miR-4651	CLIP-seq
MIRT1194457	hsa-miR-4728-5p	CLIP-seq
MIRT1194458	hsa-miR-4736	CLIP-seq
MIRT1194460	hsa-miR-4763-3p	CLIP-seq
MIRT1194462	hsa-miR-485-5p	CLIP-seq
MIRT1194463	hsa-miR-550a	CLIP-seq
MIRT2056510	hsa-miR-608	CLIP-seq
MIRT2056511	hsa-miR-637	CLIP-seq
MIRT1194464	hsa-miR-665	CLIP-seq
MIRT1194465	hsa-miR-764	CLIP-seq
MIRT1194466	hsa-miR-890	CLIP-seq
MIRT1194440	hsa-miR-1225-3p	CLIP-seq
MIRT1194441	hsa-miR-1233	CLIP-seq
MIRT2284978	hsa-miR-141	CLIP-seq
MIRT2284979	hsa-miR-200a	CLIP-seq
MIRT1194445	hsa-miR-2114	CLIP-seq
MIRT1194448	hsa-miR-3689a-3p	CLIP-seq
MIRT1194449	hsa-miR-3689c	CLIP-seq
MIRT1194451	hsa-miR-3922-5p	CLIP-seq
MIRT1194452	hsa-miR-3929	CLIP-seq
MIRT1194454	hsa-miR-4419b	CLIP-seq
MIRT1194455	hsa-miR-4433	CLIP-seq
MIRT1194456	hsa-miR-4478	CLIP-seq
MIRT1194457	hsa-miR-4728-5p	CLIP-seq
MIRT1194462	hsa-miR-485-5p	CLIP-seq
MIRT1194463	hsa-miR-550a	CLIP-seq
MIRT1194464	hsa-miR-665	CLIP-seq
MIRT1194465	hsa-miR-764	CLIP-seq
MIRT1194466	hsa-miR-890	CLIP-seq
MIRT1194445	hsa-miR-2114	CLIP-seq
MIRT1194448	hsa-miR-3689a-3p	CLIP-seq
MIRT1194449	hsa-miR-3689c	CLIP-seq
MIRT1194452	hsa-miR-3929	CLIP-seq
MIRT1194454	hsa-miR-4419b	CLIP-seq
MIRT1194456	hsa-miR-4478	CLIP-seq
MIRT1194457	hsa-miR-4728-5p	CLIP-seq
MIRT1194462	hsa-miR-485-5p	CLIP-seq
MIRT1194463	hsa-miR-550a	CLIP-seq
MIRT1194465	hsa-miR-764	CLIP-seq
MIRT1194466	hsa-miR-890	CLIP-seq
MIRT2431644	hsa-miR-3123	CLIP-seq
MIRT2431645	hsa-miR-3919	CLIP-seq
MIRT2431646	hsa-miR-4716-5p	CLIP-seq
MIRT2431647	hsa-miR-4756-3p	CLIP-seq
MIRT2431644	hsa-miR-3123	CLIP-seq
MIRT2431645	hsa-miR-3919	CLIP-seq
MIRT2431646	hsa-miR-4716-5p	CLIP-seq
MIRT2431647	hsa-miR-4756-3p	CLIP-seq
MIRT2431644	hsa-miR-3123	CLIP-seq
MIRT2431645	hsa-miR-3919	CLIP-seq
MIRT2431646	hsa-miR-4716-5p	CLIP-seq
MIRT2431647	hsa-miR-4756-3p	CLIP-seq
MIRT1194439	hsa-miR-1207-5p	CLIP-seq
MIRT1194445	hsa-miR-2114	CLIP-seq
MIRT1194447	hsa-miR-3665	CLIP-seq
MIRT1194448	hsa-miR-3689a-3p	CLIP-seq
MIRT1194449	hsa-miR-3689c	CLIP-seq
MIRT1194452	hsa-miR-3929	CLIP-seq
MIRT1194454	hsa-miR-4419b	CLIP-seq
MIRT1194456	hsa-miR-4478	CLIP-seq
MIRT1194457	hsa-miR-4728-5p	CLIP-seq
MIRT1194458	hsa-miR-4736	CLIP-seq
MIRT1194460	hsa-miR-4763-3p	CLIP-seq
MIRT1194462	hsa-miR-485-5p	CLIP-seq
MIRT1194463	hsa-miR-550a	CLIP-seq
MIRT1194465	hsa-miR-764	CLIP-seq
MIRT1194466	hsa-miR-890	CLIP-seq
MIRT1194448	hsa-miR-3689a-3p	CLIP-seq
MIRT1194449	hsa-miR-3689c	CLIP-seq
MIRT1194457	hsa-miR-4728-5p	CLIP-seq
MIRT1194445	hsa-miR-2114	CLIP-seq
MIRT1194448	hsa-miR-3689a-3p	CLIP-seq
MIRT1194449	hsa-miR-3689c	CLIP-seq
MIRT1194452	hsa-miR-3929	CLIP-seq
MIRT1194454	hsa-miR-4419b	CLIP-seq
MIRT1194456	hsa-miR-4478	CLIP-seq
MIRT1194457	hsa-miR-4728-5p	CLIP-seq
MIRT1194462	hsa-miR-485-5p	CLIP-seq
MIRT1194463	hsa-miR-550a	CLIP-seq
MIRT1194466	hsa-miR-890	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0007399	Process	Nervous system development	IBA	21873635
GO:0007399	Process	Nervous system development	ISS
GO:0016021	Component	Integral component of membrane	IEA
GO:0030133	Component	Transport vesicle	IBA	21873635
GO:0030133	Component	Transport vesicle	TAS	12463420
GO:0030426	Component	Growth cone	ISS
GO:0031410	Component	Cytoplasmic vesicle	ISS
GO:0043005	Component	Neuron projection	IBA	21873635
GO:0043005	Component	Neuron projection	ISS
GO:0043025	Component	Neuronal cell body	IBA	21873635
GO:0043025	Component	Neuronal cell body	ISS

MIM	HGNC	e!Ensembl
616630	17881	ENSG00000152954

Protein

UniProt ID

Q8IZ57

Protein name

Neurensin-1 (Neuro-p24) (Vesicular membrane protein of 24 kDa) (Vesicular membrane protein p24)

Protein function

May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension. May play a role in memory consolidation (By similarity). {ECO:0000250|UniProtKB:P97799, ECO:

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14927	Neurensin	23 → 153		Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain. Not detectable in other tissues tested. {ECO:0000269|PubMed:12463420}.

Sequence

MSSCSNVCGSRQAQAAAEGGYQRYGVRSYLHQFYEDCTASIWEYEDDFQIQRSPNRWSSV
FWKVGLISGTVFVILGLTVLAVGFLVPPKIEAFGEADFVVVDTHAVQFNSALDMYKLAGA
VLFCIGGTSMAGCLLMSVFVKSYSKEEKFLQQKFKERIADIKAHTQPVTKAPGPGETKIP
VTLSRVQNVQPLLAT

Sequence length

195

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Hirschsprung disease	Hirschsprung Disease	rs76262710, rs75996173, rs77316810, rs75076352, rs76534745, rs76764689, rs76449634, rs377767412, rs193922699, rs75030001, rs606231342, rs1553540620, rs759944122, rs1057519322, rs1057519323 View all (4 more)	22325380

Show/Hide Unknown Diseases (4)

Disease term	Disease name	Evidence	References	Source
Unknown
Huntington disease	Huntington Disease		22325380	ClinVar
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA
Insomnia	Insomnia			GWAS
Prostate cancer	Prostate cancer	Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population.		GWAS, CBGDA

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text Mining
Acquired Immunodeficiency Syndrome	Associate	1696859
Attention Deficit Disorder with Hyperactivity	Associate	19362708
Auditory Perceptual Disorders	Associate	19362708
Disruptive Impulse Control and Conduct Disorders	Associate	19362708
Dyslexia	Associate	15717286, 16385449
Hirschsprung Disease	Associate	29654647
HIV Infections	Stimulate	25998390
Infections	Associate	25341640
Leukoencephalitis Acute Hemorrhagic	Associate	23347174
Psychotic Disorders	Associate	29064472

NRSN1 (neurensin 1)