Gene Gene information from NCBI Gene database.
Entrez ID 140685
Gene name Zinc finger and BTB domain containing 46
Gene symbol ZBTB46
Synonyms (NCBI Gene)
BTBD4BZELRINZFZNF340dJ583P15.7dJ583P15.8
Chromosome 20
Chromosome location 20q13.33
miRNA miRNA information provided by mirtarbase database.
428
miRTarBase ID miRNA Experiments Reference
MIRT724734 hsa-miR-6750-3p HITS-CLIP 19536157
MIRT724733 hsa-miR-3680-5p HITS-CLIP 19536157
MIRT533046 hsa-miR-6793-3p HITS-CLIP 19536157
MIRT724732 hsa-miR-361-3p HITS-CLIP 19536157
MIRT724731 hsa-miR-6889-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000122 Process Negative regulation of transcription by RNA polymerase II ISS
GO:0000785 Component Chromatin IEA
GO:0000785 Component Chromatin ISA
GO:0000785 Component Chromatin ISS
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
614639 16094 ENSG00000130584
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q86UZ6
Protein name Zinc finger and BTB domain-containing protein 46 (BTB-ZF protein expressed in effector lymphocytes) (BZEL) (BTB/POZ domain-containing protein 4) (Zinc finger protein 340)
Protein function Functions as a transcriptional repressor for PRDM1.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00651 BTB 21 129 BTB/POZ domain Domain
PF13909 zf-H2C2_5 418 442 Domain
Sequence
MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLY
CQVQKTSEQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQA
CHDFIKAAL
DISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPANS
SGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGG
SELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFL
PTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLGPPLTPEKDDA
LHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKC
PYCSFSAMHQCILKRHMRSHTG
ERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCS
RVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPED
PRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPGGPDKDFAWLS
Sequence length 589
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Chronic osteomyelitis association rs755017 RCV000498980
Marfanoid habitus and intellectual disability Uncertain significance rs1601379733 RCV000850423
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Coronary Disease Associate 24904205
Dendritic Cell Sarcoma Follicular Associate 29743654
Histiocytic Disorders Malignant Associate 29743654
Histiocytosis Langerhans Cell Associate 29743654
Influenza Human Associate 34276655
Lymphoma Large B Cell Diffuse Associate 29743654
Multiple Myeloma Inhibit 31164886
Multiple Sclerosis Associate 23739915
Neoplasms Squamous Cell Associate 29743654
Ovarian Neoplasms Associate 28893231