Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	140032
Gene name Gene Name - the full gene name approved by the HGNC.	Ribosomal protein S4 Y-linked 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RPS4Y2
Synonyms (NCBI Gene) Gene synonyms aliases	RPS4Y2P
Chromosome Chromosome number	Y
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Yq11.223
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a ribosomal protein that is highly similar to RPS4Y1. This gene is located in the male-specific region of the Y chromosome. [provided by RefSeq, Aug 2012]

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence
GO:0003723	Function	RNA binding	IBA
GO:0003723	Function	RNA binding	IEA
GO:0003735	Function	Structural constituent of ribosome	IBA
GO:0003735	Function	Structural constituent of ribosome	IEA
GO:0005840	Component	Ribosome	IEA
GO:0006412	Process	Translation	IBA
GO:0006412	Process	Translation	IEA
GO:0019843	Function	RRNA binding	IEA
GO:0022627	Component	Cytosolic small ribosomal subunit	IBA
GO:1990904	Component	Ribonucleoprotein complex	IEA

MIM	HGNC	e!Ensembl
400030	18501	ENSG00000280969

Protein

UniProt ID

Q8TD47

Protein name

Small ribosomal subunit protein eS4, Y isoform 2 (40S ribosomal protein S4, Y isoform 2)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08071	RS4NT	3 → 39	RS4NT (NUC023) domain	Domain
PF00900	Ribosomal_S4e	95 → 169	Ribosomal family S4e	Family
PF00467	KOW	177 → 211	KOW motif	Family
PF16121	40S_S4_C	212 → 259	40S ribosomal protein S4 C-terminus	Family

Sequence

MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIVFLRNRLKYALTGDE
VKKICMQHFLKIDGKVRVDITYPAGFIDVISIEKTGEHFRLVYNTKGCFAVHRITVEEAK
YKLCKVRKITVGTKGIPHLVTHDARTIRYPDPLIKVNDTVQIDLGTGKITSFIKFDTGNV
CMVIAGANLGRVGVITNRERHPGSCDVVHVKDANGNSFATRISNIFVIGNGNKPWISLPR
GKGIRLTIAEERDKRLAAKQSSG

Sequence length

263

Interactions

View interactions

	KEGG		Reactome
	Ribosome Coronavirus disease - COVID-19		L13a-mediated translational silencing of Ceruloplasmin expression SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

RPS4Y2 (ribosomal protein S4 Y-linked 2)