FOXR2 (forkhead box R2)

Gene

• Entrez ID: 139628
• Gene name: Forkhead box R2
• Gene symbol: FOXR2
• Synonyms (NCBI Gene): FOXN6
• Chromosome: X
• Chromosome location: Xp11.21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT658088	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT658087	hsa-miR-6882-5p	HITS-CLIP	23824327
MIRT658086	hsa-miR-942-3p	HITS-CLIP	23824327
MIRT658085	hsa-miR-4457	HITS-CLIP	23824327
MIRT658084	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT658083	hsa-miR-4717-3p	HITS-CLIP	23824327
MIRT658082	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT658081	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT658080	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT658079	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT658078	hsa-miR-6837-3p	HITS-CLIP	23824327
MIRT658077	hsa-miR-513b-5p	HITS-CLIP	23824327
MIRT658076	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT658075	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT658074	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT658073	hsa-miR-23c	HITS-CLIP	23824327
MIRT658072	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT658071	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT733907	hsa-miR-1252-3p	Immunohistochemistry (IHC), Luciferase reporter assay, Microarray, Western blotting	31945729
MIRT734225	hsa-miR-1252-5p	Luciferase reporter assay, qRT-PCR, Western blotting	31945729
MIRT658088	hsa-miR-5571-5p	HITS-CLIP	23824327
MIRT658087	hsa-miR-6882-5p	HITS-CLIP	23824327
MIRT658086	hsa-miR-942-3p	HITS-CLIP	23824327
MIRT658085	hsa-miR-4457	HITS-CLIP	23824327
MIRT658084	hsa-miR-125b-2-3p	HITS-CLIP	23824327
MIRT658083	hsa-miR-4717-3p	HITS-CLIP	23824327
MIRT658082	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT658081	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT658080	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT658079	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT658078	hsa-miR-6837-3p	HITS-CLIP	23824327
MIRT658077	hsa-miR-513b-5p	HITS-CLIP	23824327
MIRT658076	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT658075	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT658074	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT658073	hsa-miR-23c	HITS-CLIP	23824327
MIRT658072	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT658071	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT1003700	hsa-miR-1252	CLIP-seq
MIRT1003701	hsa-miR-1294	CLIP-seq
MIRT1003702	hsa-miR-129-5p	CLIP-seq
MIRT1003703	hsa-miR-1323	CLIP-seq
MIRT1003704	hsa-miR-3163	CLIP-seq
MIRT1003705	hsa-miR-3662	CLIP-seq
MIRT1003706	hsa-miR-4766-3p	CLIP-seq
MIRT1003707	hsa-miR-548o	CLIP-seq
MIRT1003708	hsa-miR-548p	CLIP-seq
MIRT1997512	hsa-miR-3121-5p	CLIP-seq
MIRT2231151	hsa-miR-4798-3p	CLIP-seq
MIRT2231152	hsa-miR-668	CLIP-seq
MIRT1003702	hsa-miR-129-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	ISA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 31515488, 32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IBA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 300949
• HGNC: 30469
• e!Ensembl: ENSG00000189299

Protein

• UniProt ID: Q6PJQ5
• Protein name: Forkhead box protein R2 (Forkhead box protein N6)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00250	Forkhead	191 → 281	Forkhead domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in breast cancer cell lines and primary cancer. {ECO:0000269|PubMed:15202009}.
• Sequence:

  MDLKLKDCEFWYSLHGQVPGLLDWDMRNELFLPCTTDQCSLAEQILAKYRVGVMKPPEMP
  QKRRPSPDGDGPPCEPNLWMWVDPNILCPLGSQEAPKPSGKEDLTNISPFPQPPQKDEGS
  NCSEDKVVESLPSSSSEQSPLQKQGIHSPSDFELTEEEAEEPDDNSLQSPEMKCYQSQKL
  WQINNQEKSWQRPPLNCSHLIALALRNNPHCGLSVQEIYNFTRQHFPFFWTAPDGWKSTI
  HYNLCFLDSFEKVPDSLKDEDNARPRSCLWKLTKEGHRRFWEETRVLAFAQRERIQECMS
  QPELLTSLFDL

• Sequence length: 311