LETM2 (leucine zipper and EF-hand containing transmembrane protein 2)

Gene

• Entrez ID: 137994
• Gene name: Leucine zipper and EF-hand containing transmembrane protein 2
• Gene symbol: LETM2
• Synonyms (NCBI Gene): SLC55A2
• Chromosome: 8
• Chromosome location: 8p11.23

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT716072	hsa-miR-4438	HITS-CLIP	19536157
MIRT716071	hsa-miR-455-5p	HITS-CLIP	19536157
MIRT716070	hsa-miR-6504-3p	HITS-CLIP	19536157
MIRT716069	hsa-miR-619-5p	HITS-CLIP	19536157
MIRT716068	hsa-miR-6506-5p	HITS-CLIP	19536157
MIRT716067	hsa-miR-1227-3p	HITS-CLIP	19536157
MIRT716066	hsa-miR-5095	HITS-CLIP	19536157
MIRT716065	hsa-miR-7151-3p	HITS-CLIP	19536157
MIRT716064	hsa-miR-4659a-5p	HITS-CLIP	19536157
MIRT716063	hsa-miR-4659b-5p	HITS-CLIP	19536157
MIRT716062	hsa-miR-5089-5p	HITS-CLIP	19536157
MIRT643028	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT643026	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT643027	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT643025	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT643024	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT643023	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT643022	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT643021	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT643020	hsa-miR-1976	HITS-CLIP	23824327
MIRT643019	hsa-miR-6861-5p	HITS-CLIP	23824327
MIRT643018	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT643017	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT643016	hsa-miR-197-5p	HITS-CLIP	23824327
MIRT643015	hsa-miR-3132	HITS-CLIP	23824327
MIRT643014	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT643013	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT643012	hsa-miR-4279	HITS-CLIP	23824327
MIRT643011	hsa-miR-1229-5p	HITS-CLIP	23824327
MIRT643010	hsa-miR-498	HITS-CLIP	23824327
MIRT716072	hsa-miR-4438	HITS-CLIP	19536157
MIRT716071	hsa-miR-455-5p	HITS-CLIP	19536157
MIRT716070	hsa-miR-6504-3p	HITS-CLIP	19536157
MIRT716069	hsa-miR-619-5p	HITS-CLIP	19536157
MIRT716068	hsa-miR-6506-5p	HITS-CLIP	19536157
MIRT716067	hsa-miR-1227-3p	HITS-CLIP	19536157
MIRT716066	hsa-miR-5095	HITS-CLIP	19536157
MIRT716065	hsa-miR-7151-3p	HITS-CLIP	19536157
MIRT716064	hsa-miR-4659a-5p	HITS-CLIP	19536157
MIRT716063	hsa-miR-4659b-5p	HITS-CLIP	19536157
MIRT716062	hsa-miR-5089-5p	HITS-CLIP	19536157
MIRT643028	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT643026	hsa-miR-4722-3p	HITS-CLIP	23824327
MIRT643027	hsa-miR-6727-3p	HITS-CLIP	23824327
MIRT643025	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT643024	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT643023	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT643022	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT643021	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT643020	hsa-miR-1976	HITS-CLIP	23824327
MIRT643019	hsa-miR-6861-5p	HITS-CLIP	23824327
MIRT643018	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT643017	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT643016	hsa-miR-197-5p	HITS-CLIP	23824327
MIRT643015	hsa-miR-3132	HITS-CLIP	23824327
MIRT643014	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT643013	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT643012	hsa-miR-4279	HITS-CLIP	23824327
MIRT643011	hsa-miR-1229-5p	HITS-CLIP	23824327
MIRT643010	hsa-miR-498	HITS-CLIP	23824327

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0006851	Process	Mitochondrial calcium ion transmembrane transport	IBA
GO:0007005	Process	Mitochondrion organization	IBA
GO:0016020	Component	Membrane	IEA
GO:0022857	Function	Transmembrane transporter activity	IBA
GO:0043022	Function	Ribosome binding	IEA

Other IDs

• MIM: 620380
• HGNC: 14648
• e!Ensembl: ENSG00000165046

Protein

• UniProt ID: Q2VYF4
• Protein name: LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07766	LETM1	122 → 386	LETM1-like protein	Family

• Sequence:

  MAFYSYNSVLAIARTRFPSHFVHPTCSSYSPSCAFLHLPDSHLNKTCMKNYESKKYSDPS
  QPGNTVLHPGTRLIQKLHTSTCWLQEVPGKPQLEQATKHPQVTSPQATKETGMEIKEGKQ
  SYRQKIMDELKYYYNGFYLLWIDAKVAARMVWRLLHGQVLTRRERRRLLRTCVDFFRLVP
  FMVFLIVPFMEFLLPVFLKLFPEMLPSTFESESKKEEKQKKKMAVKLELAKFLQETMTEM
  ARRNRAKMGDASTQLSSYVKQVQTGHKPSTKEIVRFSKLFEDQLALEHLDRPQLVALCKL
  LELQTFGTNNLLRFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEE
  QLRQQLTEWQDLHLKENVPPSLLLLSRTFYLIDVKPKPIEIPLSGEAPKTDILVELPTFT
  ESKENMVDLAPQLKGTKDEDFIQPPPVTSSPITPSTPISLPKGPITSSEEPTLQAKSQMT
  AQNSKASSKGA

• Sequence length: 491