CR1L (complement C3b/C4b receptor 1 like)

Gene
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1379
Gene name Gene Name - the full gene name approved by the HGNC.
Complement C3b/C4b receptor 1 like
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CR1L
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1q32.2
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(13)
GO ID Ontology Definition Evidence Reference
GO:0002456 Process T cell mediated immunity IBA
GO:0005515 Function Protein binding IPI 32296183
GO:0005576 Component Extracellular region IEA
GO:0005615 Component Extracellular space IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
605886 2335 ENSG00000197721
Protein
Gene Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q2VPA4
Protein name Complement component receptor 1-like protein (Complement C4b-binding protein CR-1-like protein)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00084 Sushi 35 → 91 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 96 → 153 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 158 → 224 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 230 → 285 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 289 → 345 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 351 → 408 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 413 → 470 Sushi repeat (SCR repeat) Domain
PF00084 Sushi 475 → 541 Sushi repeat (SCR repeat) Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in fetal liver and to a lesser extent in fetal spleen and thymus. Expression appears to be limited to hematopoietic and fetal lymphoid tissue. {ECO:0000269|PubMed:14687939}.
Sequence
Sequence length 569
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG  
  Complement and coagulation cascades
Neutrophil extracellular trap formation
Hematopoietic cell lineage
Legionellosis
Leishmaniasis
Malaria
Tuberculosis 		 
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (2)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Alzheimer disease Alzheimer's disease or family history of Alzheimer's disease N/A N/A GWAS
Multiple Sclerosis Multiple sclerosis N/A N/A GWAS
Show/Hide Text Mining Associations (4)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Alzheimer Disease Associate 32919460, 33788842
Brain Neoplasms Associate 26849056
Dementia Associate 33788842
Inflammation Inhibit 38573776