Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
137886
Gene name Gene Name - the full gene name approved by the HGNC.
UBX domain protein 2B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
UBXN2B
Synonyms (NCBI Gene) Gene synonyms aliases
p37
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8q12.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT051130 hsa-miR-16-5p CLASH 23622248
MIRT048564 hsa-miR-100-5p CLASH 23622248
MIRT621642 hsa-miR-124-3p HITS-CLIP 23824327
MIRT621657 hsa-miR-3714 HITS-CLIP 23824327
MIRT621656 hsa-miR-3910 HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA 21873635
GO:0000132 Process Establishment of mitotic spindle orientation IGI 23649807
GO:0005515 Function Protein binding IPI 25416956, 28514442, 29997244, 31515488, 32296183
GO:0005634 Component Nucleus IBA 21873635
GO:0005783 Component Endoplasmic reticulum IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610686 27035 ENSG00000215114
Protein
UniProt ID Q14CS0
Protein name UBX domain-containing protein 2B (NSFL1 cofactor p37) (p97 cofactor p37)
Protein function Adapter protein required for Golgi and endoplasmic reticulum biogenesis (PubMed:17141156). Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis (PubMed:17141156). The complex for
PDB 8B5R
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08059 SEP 146 220 SEP domain Domain
PF00789 UBX 251 330 UBX domain Domain
Sequence
MAEGGGPEPGEQERRSSGPRPPSARDLQLALAELYEDEVKCKSSKSNRPKATVFKSPRTP
PQRFYSSEHEYSGLNIVRPSTGKIVNELFKEAREHGAVPLNEATRASGDDKSKSFTGGGY
RLGSSFCKRSEYIYGENQLQDVQILLKLWSNGFSLDDGELRPYNEPTNAQFLESVKRGEI
PLELQRLVHGGQVNLDMEDHQDQEYIKPRLRFKAFSGEGQ
KLGSLTPEIVSTPSSPEEED
KSILNAVVLIDDSVPTTKIQIRLADGSRLIQRFNSTHRILDVRNFIVQSRPEFAALDFIL
VTSFPNKELTDESLTLLEADILNTVLLQQL
K
Sequence length 331
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Narcolepsy Narcolepsy rs104894574, rs387906655 23496005
Unknown
Disease term Disease name Evidence References Source
Cholecystitis Cholecystitis GWAS
Cholelithiasis Cholelithiasis GWAS
Schizophrenia Schizophrenia GWAS
Intrahepatic Cholestasis Of Pregnancy Intrahepatic Cholestasis Of Pregnancy GWAS
Associations from Text Mining
Disease Name Relationship Type References
Uveal melanoma Associate 38246894