SGCZ (sarcoglycan zeta)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
137868
Gene name Gene Name - the full gene name approved by the HGNC.
Sarcoglycan zeta
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SGCZ
Synonyms (NCBI Gene) Gene synonyms aliases
ZSG1
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8p22
Summary Summary of gene provided in NCBI Entrez Gene.
The zeta-sarcoglycan gene measures over 465 kb and localizes to 8p22. This protein is part of the sarcoglycan complex, a group of 6 proteins. The sarcoglycans are all N-glycosylated transmembrane proteins with a short intra-cellular domain, a single trans
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(6)
miRTarBase ID miRNA Experiments Reference
MIRT1343015 hsa-miR-380 CLIP-seq
MIRT1343016 hsa-miR-3924 CLIP-seq
MIRT1343017 hsa-miR-4495 CLIP-seq
MIRT1343018 hsa-miR-4646-5p CLIP-seq
MIRT1343019 hsa-miR-4729 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(11)
GO ID Ontology Definition Evidence Reference
GO:0005737 Component Cytoplasm IEA
GO:0005856 Component Cytoskeleton IEA
GO:0016012 Component Sarcoglycan complex IBA 21873635
GO:0016012 Component Sarcoglycan complex TAS 17438352
GO:0016021 Component Integral component of membrane IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
608113 14075 ENSG00000185053
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q96LD1
Protein name Zeta-sarcoglycan (Zeta-SG) (ZSG1)
Protein function Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. May play a role in the maintenance of striated muscle membrane stability
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04790 Sarcoglycan_1 25 → 286 Sarcoglycan complex subunit protein Family
Sequence
Sequence length 299
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG  
  Cytoskeleton in muscle cells
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Dilated cardiomyopathy
Viral myocarditis 		 
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Causal Diseases (4)
Causal
Disease term Disease name dbSNP ID References
Cholelithiasis Cholelithiasis rs121918440, rs72552778, rs387906528, rs759202962, rs377160065, rs1051861187, rs757693457, rs752563752 17632509
Hypertension Hypertensive disease rs13306026 27802415, 28498854
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Rheumatoid arthritis Rheumatoid Arthritis rs587776843 31596875
Show/Hide Unknown Diseases (10)
Unknown
Disease term Disease name Evidence References Source
Neuroticism Neuroticism GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Attention Deficit Hyperactivity Disorder Attention Deficit Hyperactivity Disorder GWAS
Diabetes Diabetes GWAS
Show/Hide Text Mining Associations (9)
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 39755674
Depressive Disorder Associate 32681239
Endometriosis Associate 25083881
Leukemia Myeloid Acute Associate 24189654
Obesity Associate 28957450
Ovarian Diseases Associate 31646556
Pain Associate 32681239
Supranuclear Palsy Progressive Associate 33635380
Thyroid Neoplasms Associate 29178884