VPS37A (VPS37A subunit of ESCRT-I)

Gene

• Entrez ID: 137492
• Gene name: VPS37A subunit of ESCRT-I
• Gene symbol: VPS37A
• Synonyms (NCBI Gene): HCRP1, PQBP2, SPG53
• Chromosome: 8
• Chromosome location: 8p22
• Summary: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular b

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs150912414	C>A	Pathogenic, uncertain-significance	Coding sequence variant, non coding transcript variant, missense variant
rs211694394	A>G,T	Pathogenic	Non coding transcript variant, missense variant, synonymous variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019385	hsa-miR-148b-3p	Microarray	17612493
MIRT050734	hsa-miR-18a-5p	CLASH	23622248
MIRT651680	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT651681	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT651679	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT651678	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT552917	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT552916	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT552915	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT552919	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT552914	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT651677	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT651676	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT651675	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT651674	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT651680	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT651681	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT651679	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT651678	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT552917	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT552916	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT552915	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT552919	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT552914	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT651677	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT651676	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT651675	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT651674	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT552919	hsa-miR-371a-5p	PAR-CLIP	21572407
MIRT105313	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT105305	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT105307	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT105314	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT105320	hsa-miR-3666	PAR-CLIP	21572407
MIRT105308	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT105317	hsa-miR-4295	PAR-CLIP	21572407
MIRT105302	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT105303	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT105318	hsa-miR-4282	PAR-CLIP	21572407
MIRT552918	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT105304	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT019385	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT105306	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT552917	hsa-miR-371b-5p	PAR-CLIP	21572407
MIRT552916	hsa-miR-373-5p	PAR-CLIP	21572407
MIRT552915	hsa-miR-616-5p	PAR-CLIP	21572407
MIRT552914	hsa-miR-372-5p	PAR-CLIP	21572407
MIRT552913	hsa-miR-298	PAR-CLIP	21572407
MIRT105321	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT552912	hsa-miR-4276	PAR-CLIP	21572407
MIRT552911	hsa-miR-513c-5p	PAR-CLIP	21572407
MIRT552910	hsa-miR-514b-5p	PAR-CLIP	21572407
MIRT552909	hsa-miR-30a-3p	PAR-CLIP	21572407
MIRT552908	hsa-miR-30d-3p	PAR-CLIP	21572407
MIRT552907	hsa-miR-30e-3p	PAR-CLIP	21572407
MIRT651680	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT651681	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT651679	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT651678	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT552917	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT552916	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT552915	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT552919	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT552914	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT651677	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT651676	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT651675	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT651674	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT651680	hsa-miR-7109-3p	HITS-CLIP	23824327
MIRT651681	hsa-miR-3613-3p	HITS-CLIP	23824327
MIRT651679	hsa-miR-483-3p	HITS-CLIP	23824327
MIRT651678	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT552917	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT552916	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT552915	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT552919	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT552914	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT651677	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT651676	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT651675	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT651674	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT552919	hsa-miR-371a-5p	PAR-CLIP	21572407
MIRT105313	hsa-miR-454-3p	PAR-CLIP	21572407
MIRT105305	hsa-miR-130a-3p	PAR-CLIP	21572407
MIRT105307	hsa-miR-301a-3p	PAR-CLIP	21572407
MIRT105314	hsa-miR-301b-3p	PAR-CLIP	21572407
MIRT105320	hsa-miR-3666	PAR-CLIP	21572407
MIRT105308	hsa-miR-130b-3p	PAR-CLIP	21572407
MIRT105317	hsa-miR-4295	PAR-CLIP	21572407
MIRT105302	hsa-miR-19a-3p	PAR-CLIP	21572407
MIRT105303	hsa-miR-19b-3p	PAR-CLIP	21572407
MIRT105318	hsa-miR-4282	PAR-CLIP	21572407
MIRT552918	hsa-miR-205-3p	PAR-CLIP	21572407
MIRT105304	hsa-miR-148a-3p	PAR-CLIP	21572407
MIRT019385	hsa-miR-148b-3p	PAR-CLIP	21572407
MIRT105306	hsa-miR-152-3p	PAR-CLIP	21572407
MIRT552917	hsa-miR-371b-5p	PAR-CLIP	21572407
MIRT552916	hsa-miR-373-5p	PAR-CLIP	21572407
MIRT552915	hsa-miR-616-5p	PAR-CLIP	21572407
MIRT552914	hsa-miR-372-5p	PAR-CLIP	21572407
MIRT552913	hsa-miR-298	PAR-CLIP	21572407
MIRT105321	hsa-miR-4671-3p	PAR-CLIP	21572407
MIRT552912	hsa-miR-4276	PAR-CLIP	21572407
MIRT552911	hsa-miR-513c-5p	PAR-CLIP	21572407
MIRT552910	hsa-miR-514b-5p	PAR-CLIP	21572407
MIRT552909	hsa-miR-30a-3p	PAR-CLIP	21572407
MIRT552908	hsa-miR-30d-3p	PAR-CLIP	21572407
MIRT552907	hsa-miR-30e-3p	PAR-CLIP	21572407
MIRT1486670	hsa-miR-103b	CLIP-seq
MIRT1486671	hsa-miR-1273f	CLIP-seq
MIRT1486672	hsa-miR-130a	CLIP-seq
MIRT1486673	hsa-miR-130b	CLIP-seq
MIRT1486674	hsa-miR-143	CLIP-seq
MIRT1486675	hsa-miR-148a	CLIP-seq
MIRT1486676	hsa-miR-148b	CLIP-seq
MIRT1486677	hsa-miR-152	CLIP-seq
MIRT1486678	hsa-miR-154	CLIP-seq
MIRT1486679	hsa-miR-183	CLIP-seq
MIRT1486680	hsa-miR-194	CLIP-seq
MIRT1486681	hsa-miR-19a	CLIP-seq
MIRT1486682	hsa-miR-19b	CLIP-seq
MIRT1486683	hsa-miR-203	CLIP-seq
MIRT1486684	hsa-miR-2052	CLIP-seq
MIRT1486685	hsa-miR-2113	CLIP-seq
MIRT1486686	hsa-miR-2114	CLIP-seq
MIRT1486687	hsa-miR-2682	CLIP-seq
MIRT1486688	hsa-miR-300	CLIP-seq
MIRT1486689	hsa-miR-301a	CLIP-seq
MIRT1486690	hsa-miR-301b	CLIP-seq
MIRT1486691	hsa-miR-3074-3p	CLIP-seq
MIRT1486692	hsa-miR-3147	CLIP-seq
MIRT1486693	hsa-miR-3163	CLIP-seq
MIRT1486694	hsa-miR-3610	CLIP-seq
MIRT1486695	hsa-miR-361-5p	CLIP-seq
MIRT1486696	hsa-miR-3686	CLIP-seq
MIRT1486697	hsa-miR-371-5p	CLIP-seq
MIRT1486698	hsa-miR-381	CLIP-seq
MIRT1486699	hsa-miR-3908	CLIP-seq
MIRT1486700	hsa-miR-3914	CLIP-seq
MIRT1486701	hsa-miR-3942-5p	CLIP-seq
MIRT1486702	hsa-miR-4252	CLIP-seq
MIRT1486703	hsa-miR-4264	CLIP-seq
MIRT1486704	hsa-miR-4277	CLIP-seq
MIRT1486705	hsa-miR-4290	CLIP-seq
MIRT1486706	hsa-miR-4307	CLIP-seq
MIRT1486707	hsa-miR-4425	CLIP-seq
MIRT1486708	hsa-miR-4464	CLIP-seq
MIRT1486709	hsa-miR-449c	CLIP-seq
MIRT1486710	hsa-miR-4502	CLIP-seq
MIRT1486711	hsa-miR-4503	CLIP-seq
MIRT1486712	hsa-miR-450b-5p	CLIP-seq
MIRT1486713	hsa-miR-454	CLIP-seq
MIRT1486714	hsa-miR-4540	CLIP-seq
MIRT1486715	hsa-miR-4662a-5p	CLIP-seq
MIRT1486716	hsa-miR-4666-3p	CLIP-seq
MIRT1486717	hsa-miR-4694-5p	CLIP-seq
MIRT1486718	hsa-miR-4703-5p	CLIP-seq
MIRT1486719	hsa-miR-4708-5p	CLIP-seq
MIRT1486720	hsa-miR-4736	CLIP-seq
MIRT1486721	hsa-miR-4742-3p	CLIP-seq
MIRT1486722	hsa-miR-4747-5p	CLIP-seq
MIRT1486723	hsa-miR-4748	CLIP-seq
MIRT1486724	hsa-miR-4766-3p	CLIP-seq
MIRT1486725	hsa-miR-4770	CLIP-seq
MIRT1486726	hsa-miR-4775	CLIP-seq
MIRT1486727	hsa-miR-4790-3p	CLIP-seq
MIRT1486728	hsa-miR-4797-3p	CLIP-seq
MIRT1486729	hsa-miR-487a	CLIP-seq
MIRT1486730	hsa-miR-491-3p	CLIP-seq
MIRT1486731	hsa-miR-495	CLIP-seq
MIRT1486732	hsa-miR-513a-3p	CLIP-seq
MIRT1486733	hsa-miR-513c	CLIP-seq
MIRT1486734	hsa-miR-518a-5p	CLIP-seq
MIRT1486735	hsa-miR-527	CLIP-seq
MIRT1486736	hsa-miR-548p	CLIP-seq
MIRT1486737	hsa-miR-576-5p	CLIP-seq
MIRT1486738	hsa-miR-586	CLIP-seq
MIRT1486739	hsa-miR-587	CLIP-seq
MIRT1486740	hsa-miR-590-3p	CLIP-seq
MIRT1486741	hsa-miR-619	CLIP-seq
MIRT1486742	hsa-miR-622	CLIP-seq
MIRT1486743	hsa-miR-624	CLIP-seq
MIRT1486744	hsa-miR-657	CLIP-seq
MIRT1486745	hsa-miR-659	CLIP-seq
MIRT1486746	hsa-miR-7	CLIP-seq
MIRT1486747	hsa-miR-758	CLIP-seq
MIRT1486748	hsa-miR-759	CLIP-seq
MIRT1486749	hsa-miR-940	CLIP-seq
MIRT1486672	hsa-miR-130a	CLIP-seq
MIRT1486673	hsa-miR-130b	CLIP-seq
MIRT1486750	hsa-miR-138	CLIP-seq
MIRT1486751	hsa-miR-141	CLIP-seq
MIRT1486675	hsa-miR-148a	CLIP-seq
MIRT1486676	hsa-miR-148b	CLIP-seq
MIRT1486677	hsa-miR-152	CLIP-seq
MIRT1486681	hsa-miR-19a	CLIP-seq
MIRT1486682	hsa-miR-19b	CLIP-seq
MIRT1486752	hsa-miR-200a	CLIP-seq
MIRT1486688	hsa-miR-300	CLIP-seq
MIRT1486689	hsa-miR-301a	CLIP-seq
MIRT1486690	hsa-miR-301b	CLIP-seq
MIRT1486753	hsa-miR-3065-5p	CLIP-seq
MIRT1486692	hsa-miR-3147	CLIP-seq
MIRT1486694	hsa-miR-3610	CLIP-seq
MIRT1486754	hsa-miR-3685	CLIP-seq
MIRT1486696	hsa-miR-3686	CLIP-seq
MIRT1486698	hsa-miR-381	CLIP-seq
MIRT1486755	hsa-miR-384	CLIP-seq
MIRT1486703	hsa-miR-4264	CLIP-seq
MIRT1486704	hsa-miR-4277	CLIP-seq
MIRT1486756	hsa-miR-4420	CLIP-seq
MIRT1486707	hsa-miR-4425	CLIP-seq
MIRT1486713	hsa-miR-454	CLIP-seq
MIRT1486716	hsa-miR-4666-3p	CLIP-seq
MIRT1486717	hsa-miR-4694-5p	CLIP-seq
MIRT1486757	hsa-miR-4728-3p	CLIP-seq
MIRT1486721	hsa-miR-4742-3p	CLIP-seq
MIRT1486722	hsa-miR-4747-5p	CLIP-seq
MIRT1486728	hsa-miR-4797-3p	CLIP-seq
MIRT1486737	hsa-miR-576-5p	CLIP-seq
MIRT1486742	hsa-miR-622	CLIP-seq
MIRT1486746	hsa-miR-7	CLIP-seq
MIRT2146355	hsa-miR-1206	CLIP-seq
MIRT2146356	hsa-miR-1283	CLIP-seq
MIRT1486672	hsa-miR-130a	CLIP-seq
MIRT1486673	hsa-miR-130b	CLIP-seq
MIRT1486679	hsa-miR-183	CLIP-seq
MIRT1486683	hsa-miR-203	CLIP-seq
MIRT1486684	hsa-miR-2052	CLIP-seq
MIRT2146357	hsa-miR-2054	CLIP-seq
MIRT1486685	hsa-miR-2113	CLIP-seq
MIRT2146358	hsa-miR-221	CLIP-seq
MIRT2146359	hsa-miR-222	CLIP-seq
MIRT1486688	hsa-miR-300	CLIP-seq
MIRT1486689	hsa-miR-301a	CLIP-seq
MIRT1486690	hsa-miR-301b	CLIP-seq
MIRT1486693	hsa-miR-3163	CLIP-seq
MIRT2146360	hsa-miR-3183	CLIP-seq
MIRT2146361	hsa-miR-3202	CLIP-seq
MIRT2146362	hsa-miR-325	CLIP-seq
MIRT2146363	hsa-miR-34a	CLIP-seq
MIRT2146364	hsa-miR-34c-5p	CLIP-seq
MIRT1486694	hsa-miR-3610	CLIP-seq
MIRT2146365	hsa-miR-3647-3p	CLIP-seq
MIRT2146366	hsa-miR-3657	CLIP-seq
MIRT2146367	hsa-miR-3682-3p	CLIP-seq
MIRT1486754	hsa-miR-3685	CLIP-seq
MIRT1486696	hsa-miR-3686	CLIP-seq
MIRT2146368	hsa-miR-376c	CLIP-seq
MIRT1486698	hsa-miR-381	CLIP-seq
MIRT1486755	hsa-miR-384	CLIP-seq
MIRT1486699	hsa-miR-3908	CLIP-seq
MIRT1486701	hsa-miR-3942-5p	CLIP-seq
MIRT1486702	hsa-miR-4252	CLIP-seq
MIRT1486703	hsa-miR-4264	CLIP-seq
MIRT2146369	hsa-miR-4272	CLIP-seq
MIRT1486704	hsa-miR-4277	CLIP-seq
MIRT2146370	hsa-miR-4293	CLIP-seq
MIRT2146371	hsa-miR-449a	CLIP-seq
MIRT2146372	hsa-miR-449b	CLIP-seq
MIRT1486710	hsa-miR-4502	CLIP-seq
MIRT2146373	hsa-miR-4517	CLIP-seq
MIRT2146374	hsa-miR-4533	CLIP-seq
MIRT1486713	hsa-miR-454	CLIP-seq
MIRT1486715	hsa-miR-4662a-5p	CLIP-seq
MIRT1486716	hsa-miR-4666-3p	CLIP-seq
MIRT2146375	hsa-miR-4669	CLIP-seq
MIRT2146376	hsa-miR-4677-3p	CLIP-seq
MIRT2146377	hsa-miR-4679	CLIP-seq
MIRT1486718	hsa-miR-4703-5p	CLIP-seq
MIRT2146378	hsa-miR-4723-3p	CLIP-seq
MIRT1486721	hsa-miR-4742-3p	CLIP-seq
MIRT2146379	hsa-miR-4760-5p	CLIP-seq
MIRT1486724	hsa-miR-4766-3p	CLIP-seq
MIRT1486728	hsa-miR-4797-3p	CLIP-seq
MIRT1486734	hsa-miR-518a-5p	CLIP-seq
MIRT1486735	hsa-miR-527	CLIP-seq
MIRT2146380	hsa-miR-548u	CLIP-seq
MIRT1486737	hsa-miR-576-5p	CLIP-seq
MIRT2146381	hsa-miR-592	CLIP-seq
MIRT2146382	hsa-miR-599	CLIP-seq
MIRT2146383	hsa-miR-610	CLIP-seq
MIRT1486742	hsa-miR-622	CLIP-seq
MIRT1486745	hsa-miR-659	CLIP-seq
MIRT2146384	hsa-miR-935	CLIP-seq
MIRT2366863	hsa-miR-1257	CLIP-seq
MIRT1486672	hsa-miR-130a	CLIP-seq
MIRT1486673	hsa-miR-130b	CLIP-seq
MIRT1486675	hsa-miR-148a	CLIP-seq
MIRT1486676	hsa-miR-148b	CLIP-seq
MIRT1486677	hsa-miR-152	CLIP-seq
MIRT1486681	hsa-miR-19a	CLIP-seq
MIRT1486682	hsa-miR-19b	CLIP-seq
MIRT1486688	hsa-miR-300	CLIP-seq
MIRT1486689	hsa-miR-301a	CLIP-seq
MIRT1486690	hsa-miR-301b	CLIP-seq
MIRT2146362	hsa-miR-325	CLIP-seq
MIRT1486696	hsa-miR-3686	CLIP-seq
MIRT2366864	hsa-miR-3692	CLIP-seq
MIRT1486698	hsa-miR-381	CLIP-seq
MIRT1486755	hsa-miR-384	CLIP-seq
MIRT2366865	hsa-miR-3935	CLIP-seq
MIRT1486703	hsa-miR-4264	CLIP-seq
MIRT1486704	hsa-miR-4277	CLIP-seq
MIRT2366866	hsa-miR-4528	CLIP-seq
MIRT1486713	hsa-miR-454	CLIP-seq
MIRT1486716	hsa-miR-4666-3p	CLIP-seq
MIRT2146376	hsa-miR-4677-3p	CLIP-seq
MIRT2146377	hsa-miR-4679	CLIP-seq
MIRT1486721	hsa-miR-4742-3p	CLIP-seq
MIRT1486728	hsa-miR-4797-3p	CLIP-seq
MIRT2366867	hsa-miR-577	CLIP-seq
MIRT1486742	hsa-miR-622	CLIP-seq
MIRT1486716	hsa-miR-4666-3p	CLIP-seq
MIRT2463288	hsa-miR-2116	CLIP-seq
MIRT2463289	hsa-miR-375	CLIP-seq
MIRT2463290	hsa-miR-4273	CLIP-seq
MIRT2463291	hsa-miR-4677-5p	CLIP-seq
MIRT1486726	hsa-miR-4775	CLIP-seq
MIRT1486731	hsa-miR-495	CLIP-seq
MIRT1486740	hsa-miR-590-3p	CLIP-seq
MIRT2463292	hsa-miR-873	CLIP-seq
MIRT2463292	hsa-miR-873	CLIP-seq
MIRT1486670	hsa-miR-103b	CLIP-seq
MIRT1486672	hsa-miR-130a	CLIP-seq
MIRT1486673	hsa-miR-130b	CLIP-seq
MIRT1486751	hsa-miR-141	CLIP-seq
MIRT1486675	hsa-miR-148a	CLIP-seq
MIRT1486676	hsa-miR-148b	CLIP-seq
MIRT1486677	hsa-miR-152	CLIP-seq
MIRT1486680	hsa-miR-194	CLIP-seq
MIRT1486681	hsa-miR-19a	CLIP-seq
MIRT1486682	hsa-miR-19b	CLIP-seq
MIRT1486752	hsa-miR-200a	CLIP-seq
MIRT1486689	hsa-miR-301a	CLIP-seq
MIRT1486690	hsa-miR-301b	CLIP-seq
MIRT2660501	hsa-miR-302f	CLIP-seq
MIRT1486753	hsa-miR-3065-5p	CLIP-seq
MIRT2660502	hsa-miR-3140-3p	CLIP-seq
MIRT2660503	hsa-miR-3194-3p	CLIP-seq
MIRT2146365	hsa-miR-3647-3p	CLIP-seq
MIRT2660504	hsa-miR-3658	CLIP-seq
MIRT1486697	hsa-miR-371-5p	CLIP-seq
MIRT2660505	hsa-miR-374a	CLIP-seq
MIRT2660506	hsa-miR-374b	CLIP-seq
MIRT2660507	hsa-miR-380	CLIP-seq
MIRT1486699	hsa-miR-3908	CLIP-seq
MIRT2660508	hsa-miR-3924	CLIP-seq
MIRT1486701	hsa-miR-3942-5p	CLIP-seq
MIRT2660509	hsa-miR-4495	CLIP-seq
MIRT2366866	hsa-miR-4528	CLIP-seq
MIRT1486713	hsa-miR-454	CLIP-seq
MIRT1486716	hsa-miR-4666-3p	CLIP-seq
MIRT1486718	hsa-miR-4703-5p	CLIP-seq
MIRT1486724	hsa-miR-4766-3p	CLIP-seq
MIRT2660510	hsa-miR-488	CLIP-seq
MIRT1486732	hsa-miR-513a-3p	CLIP-seq
MIRT1486733	hsa-miR-513c	CLIP-seq
MIRT2660511	hsa-miR-561	CLIP-seq
MIRT1486737	hsa-miR-576-5p	CLIP-seq
MIRT1486672	hsa-miR-130a	CLIP-seq
MIRT1486673	hsa-miR-130b	CLIP-seq
MIRT1486689	hsa-miR-301a	CLIP-seq
MIRT1486690	hsa-miR-301b	CLIP-seq
MIRT2146365	hsa-miR-3647-3p	CLIP-seq
MIRT1486713	hsa-miR-454	CLIP-seq
MIRT1486672	hsa-miR-130a	CLIP-seq
MIRT1486673	hsa-miR-130b	CLIP-seq
MIRT1486689	hsa-miR-301a	CLIP-seq
MIRT1486690	hsa-miR-301b	CLIP-seq
MIRT1486713	hsa-miR-454	CLIP-seq
MIRT1486751	hsa-miR-141	CLIP-seq
MIRT1486752	hsa-miR-200a	CLIP-seq
MIRT2660501	hsa-miR-302f	CLIP-seq
MIRT2660502	hsa-miR-3140-3p	CLIP-seq
MIRT2660503	hsa-miR-3194-3p	CLIP-seq
MIRT2695070	hsa-miR-4462	CLIP-seq
MIRT2660510	hsa-miR-488	CLIP-seq
MIRT2660511	hsa-miR-561	CLIP-seq
MIRT2695071	hsa-miR-767-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000813	Component	ESCRT I complex	IBA
GO:0000813	Component	ESCRT I complex	IDA	18005716, 20654576, 21757351
GO:0000813	Component	ESCRT I complex	IEA
GO:0000813	Component	ESCRT I complex	IPI	18005716, 21757351
GO:0000813	Component	ESCRT I complex	ISS
GO:0000813	Component	ESCRT I complex	TAS	20588296
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005768	Component	Endosome	IEA
GO:0005813	Component	Centrosome	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006612	Process	Protein targeting to membrane	IBA
GO:0006623	Process	Protein targeting to vacuole	IBA
GO:0010008	Component	Endosome membrane	NAS	32424346
GO:0010008	Component	Endosome membrane	TAS
GO:0015031	Process	Protein transport	IEA
GO:0016020	Component	Membrane	IEA
GO:0016236	Process	Macroautophagy	IEA
GO:0016236	Process	Macroautophagy	TAS	20588296
GO:0031902	Component	Late endosome membrane	IEA
GO:0036258	Process	Multivesicular body assembly	IEA
GO:0036258	Process	Multivesicular body assembly	NAS	32424346
GO:0036258	Process	Multivesicular body assembly	TAS	20588296
GO:0039702	Process	Viral budding via host ESCRT complex	IEA
GO:0039702	Process	Viral budding via host ESCRT complex	TAS	20588296
GO:0043162	Process	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IBA
GO:0043162	Process	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IC	20654576
GO:0043162	Process	Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IMP	21757351
GO:0043328	Process	Protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	NAS	32424346
GO:0090148	Process	Membrane fission	NAS	32424346

Other IDs

• MIM: 609927
• HGNC: 24928
• e!Ensembl: ENSG00000155975

Protein

• UniProt ID: Q8NEZ2
• Protein name: Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1)
• Protein function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:152408
• PDB: 8E22
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07200	Mod_r	235 → 380	Modifier of rudimentary (Mod(r)) protein	Domain

• Tissue specificity: TISSUE SPECIFICITY: Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas. {ECO:0000269|PubMed:14623289, ECO:0000269|PubMed:227
• Sequence:

  MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTINN
  LTININILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLL
  DEFWKNPPVLAPTSTAFPYLYSNPSGMSPYASQGFPFLPPYPPQEANRSITSLSVADTVS
  SSTTSHTTAKPAAPSFGVLSNLPLPIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVS
  QLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDK
  YELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKMEID
  DFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAPL

• Sequence length: 397

Pathways

KEGG:

Endocytosis

Reactome:

Budding and maturation of HIV virion
Membrane binding and targetting of GAG proteins
Endosomal Sorting Complex Required For Transport (ESCRT)
HCMV Late Events

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Hereditary spastic paraplegia 53	Pathogenic	rs211694394	RCV000032956

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Acute myeloid leukemia	Benign	rs17502618	RCV005896701
Cervical cancer	Likely benign	rs7007753	RCV005919158
Colon adenocarcinoma	Conflicting classifications of pathogenicity	rs755402438	RCV005931981
Familial cancer of breast	Uncertain significance	rs761357127	RCV005934727
Gastric cancer	Benign	rs17502618	RCV005896704
Hepatocellular carcinoma	Benign	rs17502618	RCV005896702
Hereditary spastic paraplegia	Uncertain significance; Conflicting classifications of pathogenicity; Benign; Likely benign	rs768941323, rs531893337, rs757735101, rs778062997, rs774817335, rs201069468, rs771451141, rs773070587, rs146110170, rs199577037, rs17687375, rs17502618, rs117336150, rs145945235, rs146098391, rs143689645	RCV001847250 RCV001847273 RCV001848275 RCV001848276 RCV001848277 RCV001848278 RCV001848279 RCV001848280 RCV001848281 RCV001848282 RCV001848055 RCV001848770 RCV001848965 RCV001848990 RCV001849163 RCV001847041
Idiopathic transverse myelitis	Conflicting classifications of pathogenicity	rs150912414	RCV000625725
Malignant tumor of urinary bladder	Conflicting classifications of pathogenicity	rs755402438	RCV005931982
Melanoma	Benign	rs17502618	RCV005896706
Ovarian serous cystadenocarcinoma	Benign	rs17502618	RCV005896705
Sarcoma	Benign	rs17502618	RCV005896703
VPS37A-related disorder	Uncertain significance; Likely benign	rs200490159, rs769418698, rs368335033, rs199577037, rs373508118, rs560097044	RCV003953946 RCV003954052 RCV003939321 RCV003965386 RCV003965655 RCV003948070

Associations from Text Mining
Disease Name	Relationship Type	References
Breast Neoplasms	Associate	25550832
Cognition Disorders	Associate	33757599
Diabetic Nephropathies	Inhibit	36465646
Hereditary Breast and Ovarian Cancer Syndrome	Associate	33197651
Lymphatic Metastasis	Inhibit	31929761
Neoplasm Metastasis	Stimulate	31929761
Neoplasms	Associate	25550832, 26304749, 33197651, 37733908
Prostatic Neoplasms	Associate	31929761
Triple Negative Breast Neoplasms	Inhibit	25550832