ZNF572 (zinc finger protein 572)

Gene

• Entrez ID: 137209
• Gene name: Zinc finger protein 572
• Gene symbol: ZNF572
• Synonyms (NCBI Gene): -
• Chromosome: 8
• Chromosome location: 8q24.13

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019049	hsa-miR-335-5p	Microarray	18185580
MIRT1530204	hsa-miR-1243	CLIP-seq
MIRT1530205	hsa-miR-1290	CLIP-seq
MIRT1530206	hsa-miR-199a-5p	CLIP-seq
MIRT1530207	hsa-miR-199b-5p	CLIP-seq
MIRT1530208	hsa-miR-2052	CLIP-seq
MIRT1530209	hsa-miR-3130-5p	CLIP-seq
MIRT1530210	hsa-miR-3167	CLIP-seq
MIRT1530211	hsa-miR-3663-3p	CLIP-seq
MIRT1530212	hsa-miR-3915	CLIP-seq
MIRT1530213	hsa-miR-3928	CLIP-seq
MIRT1530214	hsa-miR-4282	CLIP-seq
MIRT1530215	hsa-miR-4307	CLIP-seq
MIRT1530216	hsa-miR-4482	CLIP-seq
MIRT1530217	hsa-miR-4711-3p	CLIP-seq
MIRT1530218	hsa-miR-4733-5p	CLIP-seq
MIRT1530219	hsa-miR-4796-3p	CLIP-seq
MIRT1530220	hsa-miR-513a-3p	CLIP-seq
MIRT1530221	hsa-miR-514	CLIP-seq
MIRT1530222	hsa-miR-514b-3p	CLIP-seq
MIRT1530223	hsa-miR-648	CLIP-seq
MIRT1530224	hsa-miR-876-5p	CLIP-seq
MIRT1921353	hsa-miR-330-3p	CLIP-seq
MIRT1921354	hsa-miR-4422	CLIP-seq
MIRT1921353	hsa-miR-330-3p	CLIP-seq
MIRT1921354	hsa-miR-4422	CLIP-seq
MIRT2160302	hsa-miR-4520a-3p	CLIP-seq
MIRT1530204	hsa-miR-1243	CLIP-seq
MIRT2379630	hsa-miR-144	CLIP-seq
MIRT2379631	hsa-miR-3654	CLIP-seq
MIRT2379632	hsa-miR-3975	CLIP-seq
MIRT2160302	hsa-miR-4520a-3p	CLIP-seq
MIRT2379633	hsa-miR-4638-3p	CLIP-seq
MIRT2379634	hsa-miR-4645-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IBA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IBA
GO:0001817	Process	Regulation of cytokine production	IBA
GO:0002682	Process	Regulation of immune system process	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 31515488, 32296183, 32814053
GO:0005634	Component	Nucleus	IDA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0042802	Function	Identical protein binding	IPI	32296183
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q7Z3I7
• Protein name: Zinc finger protein 572
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	132 → 154	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	160 → 182	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	188 → 210	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	216 → 238	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	244 → 266	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	272 → 294	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	328 → 350	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	384 → 406	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	412 → 434	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	440 → 462	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	468 → 490	Zinc finger, C2H2 type	Domain

• Sequence:

  MEQEKKLLVSDSNSFMERESLKSPFTGDTSMNNLETVHHNNSKADKLKEKPSEWSKRHRP
  QHYKHEDAKEMPLTWVQDEIWCHDSYESDGKSENWGNFIAKEEEKPNHQEWDSGEHTNAC
  VQQNSSFVDRPYKCSECWKSFSNSSHLRTHQRTHSGEKPYKCSECAKCFCNSSHLIQHLR
  MHTGEKPYQCGECGKSFSNTSHLIIHERTHTGEKPYKCPECGKRFSSSSHLIQHHRSHTG
  EKPYECSVCGKGFSHSYVLIEHQRTHTGEKPYKCPDCGKSFSQSSSLIRHQRTHTGEKPY
  KCLECEKSFGCNSTLIKHQRIHTGEKPYQCPECGKNFSRSSNLITHQKMHTGEKSYESSE
  YEESLGQNCNVIEECRIQLGEKPYRCCECGKSFGLSSHLIRHQRTHTGEKPYRCSECWKT
  FSQSSTLVIHQRTHTGEKPYKCPDCGESFSQSFNLIRHRRTHIGEKPYKCTSCEKCFSRS
  AYLSQHRKIHVEKPFESPDVGDFPHEWTWKNCSGEMPFISSFSVSNSSS

• Sequence length: 529

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
ANDROGENETIC ALOPECIA	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PROLIFERATIVE DIABETIC RETINOPATHY	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations