Gene Gene information from NCBI Gene database.
Entrez ID 1368
Gene name Carboxypeptidase M
Gene symbol CPM
Synonyms (NCBI Gene)
-
Chromosome 12
Chromosome location 12q15
Summary The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 p
miRNA miRNA information provided by mirtarbase database.
487
miRTarBase ID miRNA Experiments Reference
MIRT022624 hsa-miR-124-3p Microarray 18668037
MIRT029472 hsa-miR-26b-5p Microarray 19088304
MIRT708439 hsa-miR-21-3p HITS-CLIP 19536157
MIRT708438 hsa-miR-3591-3p HITS-CLIP 19536157
MIRT708437 hsa-miR-3190-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
22
GO ID Ontology Definition Evidence Reference
GO:0004180 Function Carboxypeptidase activity IEA
GO:0004180 Function Carboxypeptidase activity TAS 7797563
GO:0004181 Function Metallocarboxypeptidase activity IBA
GO:0004181 Function Metallocarboxypeptidase activity IEA
GO:0004181 Function Metallocarboxypeptidase activity TAS 2753907
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
114860 2311 ENSG00000135678
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P14384
Protein name Carboxypeptidase M (CPM) (EC 3.4.17.12)
Protein function Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degrad
PDB 1UWY
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00246 Peptidase_M14 28 303 Zinc carboxypeptidase Domain
PF13620 CarboxypepD_reg 314 387 Domain
Sequence
Sequence length 443
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Post-translational modification: synthesis of GPI-anchored proteins