CPM (carboxypeptidase M)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1368 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Carboxypeptidase M |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CPM |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q15 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 p |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | P14384 | |||||||||||||||
Protein name | Carboxypeptidase M (CPM) (EC 3.4.17.12) | |||||||||||||||
Protein function | Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degrad | |||||||||||||||
PDB | 1UWY | |||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 443 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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