MPLKIP (M-phase specific PLK1 interacting protein)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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136647 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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M-phase specific PLK1 interacting protein |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MPLKIP |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ABHS, C7orf11, ORF20, TTD4 |
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Chromosome
Chromosome number
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7 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7p14.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q8TAP9 | ||||||||||
| Protein name | M-phase-specific PLK1-interacting protein (TTD non-photosensitive 1 protein) | ||||||||||
| Protein function | May play a role in maintenance of cell cycle integrity by regulating mitosis or cytokinesis. | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed at highest levels in liver and kidney; intermediate expression in skeletal muscle, pancreas, heart and placenta; low expression in brain and lung. Expressed in epidermis and hair follicles. {ECO:0000269|PubMed:11829489, ECO:0 | ||||||||||
| Sequence |
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| Sequence length | 179 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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