SVOPL (SVOP like)

Gene Gene information from NCBI Gene database.
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID 136306
Gene name SVOP like
Gene symbol SVOPL
Synonyms (NCBI Gene)
SLC22B5
Chromosome 7
Chromosome location 7q34
Summary The protein encoded by this gene is thought to be a member of solute carrier family 22, which includes transmembrane proteins that transport toxins and drugs from the body. This gene is a paralog of the SVOP gene that encodes synaptic vesicle 2-related pr
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
4
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all (4)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0016020 Component Membrane IEA
GO:0022857 Function Transmembrane transporter activity IEA
GO:0055085 Process Transmembrane transport IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
611700 27034 ENSG00000157703
Protein Protein information from UniProt database.
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8N434
Protein name Putative transporter SVOPL (SV2-related protein-like) (SVOP-like protein)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07690 MFS_1 50 → 310 Major Facilitator Superfamily Family
PF00083 Sugar_tr 338 → 492 Sugar (and other) transporter Family
Sequence
Sequence length 492
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Gene Gene ontology Other IDs Protein Associated diseases
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Show/Hide Unknown Diseases (4)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CENTRAL NERVOUS SYSTEM CANCER — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
HYDROPS FETALIS, NON-IMMUNE — Disgenet
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Non-immune hydrops fetalis Uncertain significance ClinVar
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SQUAMOUS CELL LUNG CARCINOMA — GWAS catalog
★★★★★
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Show/Hide Text Mining Associations (4)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Chromosome 7 trisomy mosaic Associate 24247273
★★★★★
★☆☆☆☆
Found in Text Mining only
Disease Associate 37337823
★★★★★
★☆☆☆☆
Found in Text Mining only
Neurocognitive Disorders Associate 27862604
★★★★★
★☆☆☆☆
Found in Text Mining only
Pseudohypoparathyroidism Associate 26819647
★★★★★
★☆☆☆☆
Found in Text Mining only