Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	1363
Gene name	Carboxypeptidase E
Gene symbol	CPE
Synonyms (NCBI Gene)	BDVSCPHIDDHH
Chromosome	4
Chromosome location	4q32.3
Summary	This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in t

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1579283609	C>-	Pathogenic	Coding sequence variant, frameshift variant

334

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018916	hsa-miR-335-5p	Microarray	18185580
MIRT050834	hsa-miR-17-5p	CLASH	23622248
MIRT683778	hsa-miR-5197-5p	HITS-CLIP	23313552
MIRT683777	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT683776	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT683775	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT683774	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT683773	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT683772	hsa-miR-940	HITS-CLIP	23313552
MIRT683771	hsa-miR-3929	HITS-CLIP	23313552
MIRT683770	hsa-miR-4419b	HITS-CLIP	23313552
MIRT683769	hsa-miR-4478	HITS-CLIP	23313552
MIRT683768	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT683767	hsa-miR-4459	HITS-CLIP	23313552
MIRT683766	hsa-miR-665	HITS-CLIP	23313552
MIRT683765	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT683764	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT683763	hsa-miR-1827	HITS-CLIP	23313552
MIRT683762	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT683761	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT683760	hsa-miR-4327	HITS-CLIP	23313552
MIRT683759	hsa-miR-3612	HITS-CLIP	23313552
MIRT683758	hsa-miR-650	HITS-CLIP	23313552
MIRT683757	hsa-miR-3622b-5p	HITS-CLIP	23313552
MIRT683756	hsa-miR-106a-3p	HITS-CLIP	23313552
MIRT679796	hsa-miR-4740-3p	HITS-CLIP	23824327
MIRT679795	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679794	hsa-miR-3199	HITS-CLIP	23824327
MIRT679793	hsa-miR-8052	HITS-CLIP	23824327
MIRT679792	hsa-miR-365a-5p	HITS-CLIP	23824327
MIRT679791	hsa-miR-365b-5p	HITS-CLIP	23824327
MIRT640576	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT640575	hsa-miR-1972	HITS-CLIP	23824327
MIRT640574	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT640573	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT678956	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT640572	hsa-miR-1207-5p	HITS-CLIP	23824327
MIRT640571	hsa-miR-4763-3p	HITS-CLIP	23824327
MIRT640570	hsa-miR-4736	HITS-CLIP	23824327
MIRT640569	hsa-miR-4284	HITS-CLIP	23824327
MIRT640568	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT640567	hsa-miR-7977	HITS-CLIP	23824327
MIRT640566	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT640565	hsa-miR-7150	HITS-CLIP	23824327
MIRT640564	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT640563	hsa-miR-1271-5p	HITS-CLIP	23824327
MIRT640562	hsa-miR-96-5p	HITS-CLIP	23824327
MIRT668919	hsa-miR-8485	HITS-CLIP	23824327
MIRT668918	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT668917	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT668916	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT668915	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT668914	hsa-miR-8064	HITS-CLIP	23824327
MIRT668913	hsa-miR-7703	HITS-CLIP	23824327
MIRT640576	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT640575	hsa-miR-1972	HITS-CLIP	23824327
MIRT640574	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT640573	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT640572	hsa-miR-1207-5p	HITS-CLIP	23824327
MIRT640571	hsa-miR-4763-3p	HITS-CLIP	23824327
MIRT640570	hsa-miR-4736	HITS-CLIP	23824327
MIRT640567	hsa-miR-7977	HITS-CLIP	23824327
MIRT640566	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT640565	hsa-miR-7150	HITS-CLIP	23824327
MIRT640564	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT640563	hsa-miR-1271-5p	HITS-CLIP	23824327
MIRT640562	hsa-miR-96-5p	HITS-CLIP	23824327
MIRT640576	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT640575	hsa-miR-1972	HITS-CLIP	23824327
MIRT640574	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT640573	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT640572	hsa-miR-1207-5p	HITS-CLIP	23824327
MIRT640571	hsa-miR-4763-3p	HITS-CLIP	23824327
MIRT640570	hsa-miR-4736	HITS-CLIP	23824327
MIRT640569	hsa-miR-4284	HITS-CLIP	23824327
MIRT640568	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT640567	hsa-miR-7977	HITS-CLIP	23824327
MIRT640566	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT640565	hsa-miR-7150	HITS-CLIP	23824327
MIRT640564	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT640563	hsa-miR-1271-5p	HITS-CLIP	23824327
MIRT640562	hsa-miR-96-5p	HITS-CLIP	23824327
MIRT638846	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT638845	hsa-miR-5007-5p	HITS-CLIP	23824327
MIRT638844	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT638843	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT638842	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT638841	hsa-miR-3672	HITS-CLIP	23824327
MIRT638840	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT638839	hsa-miR-8055	HITS-CLIP	23824327
MIRT309648	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT570952	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT570951	hsa-miR-3154	PAR-CLIP	20371350
MIRT570950	hsa-miR-3125	PAR-CLIP	20371350
MIRT570949	hsa-miR-3916	PAR-CLIP	20371350
MIRT570948	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT570947	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT570945	hsa-miR-3185	PAR-CLIP	20371350
MIRT570946	hsa-miR-7515	PAR-CLIP	20371350
MIRT570944	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT570943	hsa-miR-4784	PAR-CLIP	20371350
MIRT570942	hsa-miR-765	PAR-CLIP	20371350
MIRT570941	hsa-miR-3153	PAR-CLIP	20371350
MIRT570939	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT570940	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT570952	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT570951	hsa-miR-3154	PAR-CLIP	20371350
MIRT570950	hsa-miR-3125	PAR-CLIP	20371350
MIRT570949	hsa-miR-3916	PAR-CLIP	20371350
MIRT570948	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT570947	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT570945	hsa-miR-3185	PAR-CLIP	20371350
MIRT570946	hsa-miR-7515	PAR-CLIP	20371350
MIRT570944	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT570943	hsa-miR-4784	PAR-CLIP	20371350
MIRT570942	hsa-miR-765	PAR-CLIP	20371350
MIRT570941	hsa-miR-3153	PAR-CLIP	20371350
MIRT570939	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT570940	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT440891	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT440889	hsa-miR-379-3p	HITS-CLIP	24374217
MIRT440888	hsa-miR-544a	HITS-CLIP	24374217
MIRT440891	hsa-miR-485-5p	HITS-CLIP	24374217
MIRT440889	hsa-miR-379-3p	HITS-CLIP	24374217
MIRT440888	hsa-miR-544a	HITS-CLIP	24374217
MIRT309648	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT309648	hsa-miR-129-5p	HITS-CLIP	27418678
MIRT638841	hsa-miR-3672	HITS-CLIP	27418678
MIRT638841	hsa-miR-3672	HITS-CLIP	27418678
MIRT638843	hsa-miR-4524a-3p	HITS-CLIP	27418678
MIRT638843	hsa-miR-4524a-3p	HITS-CLIP	27418678
MIRT638846	hsa-miR-4797-5p	HITS-CLIP	27418678
MIRT638846	hsa-miR-4797-5p	HITS-CLIP	27418678
MIRT638845	hsa-miR-5007-5p	HITS-CLIP	27418678
MIRT638845	hsa-miR-5007-5p	HITS-CLIP	27418678
MIRT638844	hsa-miR-6773-3p	HITS-CLIP	27418678
MIRT638844	hsa-miR-6773-3p	HITS-CLIP	27418678
MIRT638840	hsa-miR-6864-3p	HITS-CLIP	27418678
MIRT638840	hsa-miR-6864-3p	HITS-CLIP	27418678
MIRT638842	hsa-miR-6879-3p	HITS-CLIP	27418678
MIRT638839	hsa-miR-8055	HITS-CLIP	27418678
MIRT638839	hsa-miR-8055	HITS-CLIP	27418678
MIRT683778	hsa-miR-5197-5p	HITS-CLIP	23313552
MIRT683777	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT683776	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT683775	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT683774	hsa-miR-6808-5p	HITS-CLIP	23313552
MIRT683773	hsa-miR-6893-5p	HITS-CLIP	23313552
MIRT683772	hsa-miR-940	HITS-CLIP	23313552
MIRT683771	hsa-miR-3929	HITS-CLIP	23313552
MIRT683770	hsa-miR-4419b	HITS-CLIP	23313552
MIRT683769	hsa-miR-4478	HITS-CLIP	23313552
MIRT683768	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT683767	hsa-miR-4459	HITS-CLIP	23313552
MIRT683766	hsa-miR-665	HITS-CLIP	23313552
MIRT683765	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT683764	hsa-miR-4649-3p	HITS-CLIP	23313552
MIRT683763	hsa-miR-1827	HITS-CLIP	23313552
MIRT683762	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT683761	hsa-miR-7160-5p	HITS-CLIP	23313552
MIRT683760	hsa-miR-4327	HITS-CLIP	23313552
MIRT683759	hsa-miR-3612	HITS-CLIP	23313552
MIRT683758	hsa-miR-650	HITS-CLIP	23313552
MIRT683757	hsa-miR-3622b-5p	HITS-CLIP	23313552
MIRT683756	hsa-miR-106a-3p	HITS-CLIP	23313552
MIRT679796	hsa-miR-4740-3p	HITS-CLIP	23824327
MIRT679795	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT679794	hsa-miR-3199	HITS-CLIP	23824327
MIRT679793	hsa-miR-8052	HITS-CLIP	23824327
MIRT679792	hsa-miR-365a-5p	HITS-CLIP	23824327
MIRT679791	hsa-miR-365b-5p	HITS-CLIP	23824327
MIRT640576	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT640575	hsa-miR-1972	HITS-CLIP	23824327
MIRT640574	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT640573	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT678956	hsa-miR-6847-3p	HITS-CLIP	23824327
MIRT640572	hsa-miR-1207-5p	HITS-CLIP	23824327
MIRT640571	hsa-miR-4763-3p	HITS-CLIP	23824327
MIRT640570	hsa-miR-4736	HITS-CLIP	23824327
MIRT640569	hsa-miR-4284	HITS-CLIP	23824327
MIRT640568	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT640567	hsa-miR-7977	HITS-CLIP	23824327
MIRT640566	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT640565	hsa-miR-7150	HITS-CLIP	23824327
MIRT640564	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT640563	hsa-miR-1271-5p	HITS-CLIP	23824327
MIRT640562	hsa-miR-96-5p	HITS-CLIP	23824327
MIRT668919	hsa-miR-8485	HITS-CLIP	23824327
MIRT668918	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT668917	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT668916	hsa-miR-6801-3p	HITS-CLIP	23824327
MIRT668915	hsa-miR-6810-3p	HITS-CLIP	23824327
MIRT668914	hsa-miR-8064	HITS-CLIP	23824327
MIRT668913	hsa-miR-7703	HITS-CLIP	23824327
MIRT640576	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT640575	hsa-miR-1972	HITS-CLIP	23824327
MIRT640574	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT640573	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT640572	hsa-miR-1207-5p	HITS-CLIP	23824327
MIRT640571	hsa-miR-4763-3p	HITS-CLIP	23824327
MIRT640570	hsa-miR-4736	HITS-CLIP	23824327
MIRT640567	hsa-miR-7977	HITS-CLIP	23824327
MIRT640566	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT640565	hsa-miR-7150	HITS-CLIP	23824327
MIRT640564	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT640563	hsa-miR-1271-5p	HITS-CLIP	23824327
MIRT640562	hsa-miR-96-5p	HITS-CLIP	23824327
MIRT640576	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT640575	hsa-miR-1972	HITS-CLIP	23824327
MIRT640574	hsa-miR-214-5p	HITS-CLIP	23824327
MIRT640573	hsa-miR-6811-3p	HITS-CLIP	23824327
MIRT640572	hsa-miR-1207-5p	HITS-CLIP	23824327
MIRT640571	hsa-miR-4763-3p	HITS-CLIP	23824327
MIRT640570	hsa-miR-4736	HITS-CLIP	23824327
MIRT640569	hsa-miR-4284	HITS-CLIP	23824327
MIRT640568	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT640567	hsa-miR-7977	HITS-CLIP	23824327
MIRT640566	hsa-miR-6514-3p	HITS-CLIP	23824327
MIRT640565	hsa-miR-7150	HITS-CLIP	23824327
MIRT640564	hsa-miR-182-5p	HITS-CLIP	23824327
MIRT640563	hsa-miR-1271-5p	HITS-CLIP	23824327
MIRT640562	hsa-miR-96-5p	HITS-CLIP	23824327
MIRT638846	hsa-miR-4797-5p	HITS-CLIP	23824327
MIRT638845	hsa-miR-5007-5p	HITS-CLIP	23824327
MIRT638844	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT638843	hsa-miR-4524a-3p	HITS-CLIP	23824327
MIRT638842	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT638841	hsa-miR-3672	HITS-CLIP	23824327
MIRT638840	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT638839	hsa-miR-8055	HITS-CLIP	23824327
MIRT309648	hsa-miR-129-5p	HITS-CLIP	23824327
MIRT570952	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT570951	hsa-miR-3154	PAR-CLIP	20371350
MIRT570950	hsa-miR-3125	PAR-CLIP	20371350
MIRT570949	hsa-miR-3916	PAR-CLIP	20371350
MIRT570948	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT570947	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT570945	hsa-miR-3185	PAR-CLIP	20371350
MIRT570946	hsa-miR-7515	PAR-CLIP	20371350
MIRT570944	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT570943	hsa-miR-4784	PAR-CLIP	20371350
MIRT570942	hsa-miR-765	PAR-CLIP	20371350
MIRT570941	hsa-miR-3153	PAR-CLIP	20371350
MIRT570939	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT570940	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT570952	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT570951	hsa-miR-3154	PAR-CLIP	20371350
MIRT570950	hsa-miR-3125	PAR-CLIP	20371350
MIRT570949	hsa-miR-3916	PAR-CLIP	20371350
MIRT570948	hsa-miR-6859-5p	PAR-CLIP	20371350
MIRT570947	hsa-miR-5584-5p	PAR-CLIP	20371350
MIRT570945	hsa-miR-3185	PAR-CLIP	20371350
MIRT570946	hsa-miR-7515	PAR-CLIP	20371350
MIRT570944	hsa-miR-3150b-3p	PAR-CLIP	20371350
MIRT570943	hsa-miR-4784	PAR-CLIP	20371350
MIRT570942	hsa-miR-765	PAR-CLIP	20371350
MIRT570941	hsa-miR-3153	PAR-CLIP	20371350
MIRT570939	hsa-miR-6733-5p	PAR-CLIP	20371350
MIRT570940	hsa-miR-6739-5p	PAR-CLIP	20371350
MIRT905839	hsa-miR-196a	CLIP-seq
MIRT905840	hsa-miR-196b	CLIP-seq
MIRT905841	hsa-miR-3065-3p	CLIP-seq
MIRT905842	hsa-miR-30a	CLIP-seq
MIRT905843	hsa-miR-30b	CLIP-seq
MIRT905844	hsa-miR-30c	CLIP-seq
MIRT905845	hsa-miR-30d	CLIP-seq
MIRT905846	hsa-miR-30e	CLIP-seq
MIRT905847	hsa-miR-3646	CLIP-seq
MIRT905848	hsa-miR-3662	CLIP-seq
MIRT905849	hsa-miR-3927	CLIP-seq
MIRT905850	hsa-miR-4496	CLIP-seq
MIRT905851	hsa-miR-4659a-3p	CLIP-seq
MIRT905852	hsa-miR-4659b-3p	CLIP-seq
MIRT905853	hsa-miR-548aa	CLIP-seq
MIRT2204574	hsa-miR-3613-3p	CLIP-seq
MIRT905851	hsa-miR-4659a-3p	CLIP-seq
MIRT905852	hsa-miR-4659b-3p	CLIP-seq
MIRT2507965	hsa-miR-101	CLIP-seq
MIRT2507966	hsa-miR-1265	CLIP-seq
MIRT2507967	hsa-miR-1284	CLIP-seq
MIRT2507968	hsa-miR-144	CLIP-seq
MIRT2507969	hsa-miR-2392	CLIP-seq
MIRT2507970	hsa-miR-25	CLIP-seq
MIRT2507971	hsa-miR-3133	CLIP-seq
MIRT2507972	hsa-miR-3135	CLIP-seq
MIRT2507973	hsa-miR-32	CLIP-seq
MIRT2507974	hsa-miR-33a	CLIP-seq
MIRT2507975	hsa-miR-33b	CLIP-seq
MIRT2204574	hsa-miR-3613-3p	CLIP-seq
MIRT2507976	hsa-miR-363	CLIP-seq
MIRT2507977	hsa-miR-367	CLIP-seq
MIRT2507978	hsa-miR-369-3p	CLIP-seq
MIRT2507979	hsa-miR-371b-5p	CLIP-seq
MIRT2507980	hsa-miR-4275	CLIP-seq
MIRT2507981	hsa-miR-4470	CLIP-seq
MIRT2507982	hsa-miR-4503	CLIP-seq
MIRT2507983	hsa-miR-4511	CLIP-seq
MIRT2507984	hsa-miR-4735-5p	CLIP-seq
MIRT2507985	hsa-miR-4775	CLIP-seq
MIRT2507986	hsa-miR-488	CLIP-seq
MIRT2507987	hsa-miR-544	CLIP-seq
MIRT2507988	hsa-miR-582-5p	CLIP-seq
MIRT2507989	hsa-miR-590-3p	CLIP-seq
MIRT2507990	hsa-miR-888	CLIP-seq
MIRT2507991	hsa-miR-92a	CLIP-seq
MIRT2507992	hsa-miR-92b	CLIP-seq
MIRT2507965	hsa-miR-101	CLIP-seq
MIRT2507966	hsa-miR-1265	CLIP-seq
MIRT2507968	hsa-miR-144	CLIP-seq
MIRT2507969	hsa-miR-2392	CLIP-seq
MIRT2507970	hsa-miR-25	CLIP-seq
MIRT2507971	hsa-miR-3133	CLIP-seq
MIRT2507972	hsa-miR-3135	CLIP-seq
MIRT2507973	hsa-miR-32	CLIP-seq
MIRT2507974	hsa-miR-33a	CLIP-seq
MIRT2507975	hsa-miR-33b	CLIP-seq
MIRT2204574	hsa-miR-3613-3p	CLIP-seq
MIRT2507976	hsa-miR-363	CLIP-seq
MIRT2507977	hsa-miR-367	CLIP-seq
MIRT2507978	hsa-miR-369-3p	CLIP-seq
MIRT2507979	hsa-miR-371b-5p	CLIP-seq
MIRT2507980	hsa-miR-4275	CLIP-seq
MIRT2507981	hsa-miR-4470	CLIP-seq
MIRT2507982	hsa-miR-4503	CLIP-seq
MIRT2507983	hsa-miR-4511	CLIP-seq
MIRT2507984	hsa-miR-4735-5p	CLIP-seq
MIRT2507985	hsa-miR-4775	CLIP-seq
MIRT2507986	hsa-miR-488	CLIP-seq
MIRT2507987	hsa-miR-544	CLIP-seq
MIRT2507988	hsa-miR-582-5p	CLIP-seq
MIRT2507989	hsa-miR-590-3p	CLIP-seq
MIRT2507990	hsa-miR-888	CLIP-seq
MIRT2507991	hsa-miR-92a	CLIP-seq
MIRT2507992	hsa-miR-92b	CLIP-seq

Show/Hide all (39)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003214	Process	Cardiac left ventricle morphogenesis	IMP	19593212
GO:0004180	Function	Carboxypeptidase activity	IEA
GO:0004180	Function	Carboxypeptidase activity	TAS	9019408
GO:0004181	Function	Metallocarboxypeptidase activity	IBA
GO:0004181	Function	Metallocarboxypeptidase activity	IEA
GO:0005515	Function	Protein binding	IPI	32814053
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005794	Component	Golgi apparatus	IDA	19166515
GO:0005886	Component	Plasma membrane	TAS	9019408
GO:0006508	Process	Proteolysis	IEA
GO:0006518	Process	Peptide metabolic process	IBA
GO:0007154	Process	Cell communication	IEA
GO:0007218	Process	Neuropeptide signaling pathway	NAS	2334405
GO:0008104	Process	Intracellular protein localization	IEA
GO:0008233	Function	Peptidase activity	IEA
GO:0008237	Function	Metallopeptidase activity	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0012505	Component	Endomembrane system	IEA
GO:0016020	Component	Membrane	IEA
GO:0016055	Process	Wnt signaling pathway	IDA	22824791
GO:0016485	Process	Protein processing	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0023052	Process	Signaling	IEA
GO:0030070	Process	Insulin processing	IEA
GO:0030072	Process	Peptide hormone secretion	IEA
GO:0030133	Component	Transport vesicle	IEA
GO:0030141	Component	Secretory granule	IEA
GO:0030658	Component	Transport vesicle membrane	IEA
GO:0030667	Component	Secretory granule membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0033366	Process	Protein localization to secretory granule	IEA
GO:0036211	Process	Protein modification process	NAS	2334405
GO:0042043	Function	Neurexin family protein binding	IPI	19166515
GO:0046872	Function	Metal ion binding	IEA
GO:0050839	Function	Cell adhesion molecule binding	IPI	19166515
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0072657	Process	Protein localization to membrane	IDA	19166515

MIM	HGNC	e!Ensembl
114855	2303	ENSG00000109472

P16870

Protein name

Carboxypeptidase E (CPE) (EC 3.4.17.10) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase)

Protein function

Sorting receptor that directs prohormones to the regulated secretory pathway. Also acts as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial end

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00246	Peptidase_M14	59 → 364	Zinc carboxypeptidase	Domain
PF13620	CarboxypepD_reg	375 → 450		Domain

Sequence

MAGRGGSALLALCGALAACGWLLGAEAQEPGAPAAGMRRRRRLQQEDGISFEYHRYPELR
EALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVG
RELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRS
NAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIP
FVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPC
RKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWED
NKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVEGIDHDVTSAKDGDYWRLLIPGNYK
LTASAPGYLAITKKVAVPYSPAAGVDFELESFSERKEEEKEELMEWWKMMSETLNF

Sequence length

476

Interactions

View interactions

	KEGG
	Type I diabetes mellitus

Show/Hide Causal Diseases (2)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
BDV syndrome	Pathogenic	rs1298858763, rs1317332155, rs1579283609, rs768504422	RCV001418305 RCV001762730 RCV001766669 RCV001815013
Blakemore-Durmaz-Vasileiou (BDV) syndrome	Pathogenic	rs1317332155	RCV001579305

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
CPE-related disorder	Uncertain significance; Benign; Likely benign	rs141075309, rs568666068, rs145229675, rs59371445, rs144687736, rs148489430, rs762963410, rs140738622, rs376055726, rs758176349, rs1451976804, rs374345764, rs202238519, rs202048102, rs896963496 View all (37 more)	RCV003416552 RCV004749818 RCV004749799 RCV003978494 RCV003933488 RCV003933498 RCV004749868 RCV003913764 RCV003936536 RCV003409959 RCV003410184 RCV004750334 RCV003906621 RCV003427704 RCV003397018 RCV003420777 RCV003420799 RCV003406128 RCV003408694 RCV003427872 RCV003412377 RCV003408537 RCV003421136 RCV003404410 RCV003394335 RCV003420953 RCV003966408 RCV003939061 RCV003980982 RCV003919366 RCV003896729 RCV003907171 RCV003929807 RCV003981528 RCV003893803 RCV003894199 RCV003902291 RCV003894402 RCV003894442 RCV003904575 RCV003981398 RCV003964574 RCV003901691 RCV003913925 RCV003942052 RCV003982171 RCV003957342 RCV003969501 RCV003969070 RCV003966997 RCV004750459 RCV003983237

Show/Hide Text Mining Associations (58)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Abortion Veterinary	Associate	12682135
ACTH Secreting Pituitary Adenoma	Associate	31319379
Alzheimer Disease	Associate	31113950
Autistic Disorder	Associate	28316770
Bile Duct Diseases	Associate	40596471
Bone Diseases Metabolic	Associate	32936766
Carcinogenesis	Associate	35528956
Carcinoma Embryonal	Associate	27803193, 29898407
Carcinoma Hepatocellular	Associate	26803519, 35328535
Clostridium Infections	Associate	9431915
Colorectal Neoplasms	Associate	21061162, 23852859
Colorectal Neoplasms	Stimulate	24006921
Developmental Disabilities	Associate	32936766
Diabetes Mellitus	Associate	32936766
Diabetes Mellitus Type 1	Associate	31442418
Diabetes Mellitus Type 2	Associate	26120850, 34029697
Diarrhea	Associate	12682135, 16452442, 9431915
Endodermal Sinus Tumor	Associate	27803193
Enterocolitis Pseudomembranous	Associate	16452442, 25135687
Exfoliation Syndrome	Inhibit	30842085
Foodborne Diseases	Associate	10919775, 11292780, 12117935, 12682135, 17905877, 23027533, 9431915
Gallstones	Associate	26228366
Gastroenteritis	Associate	31553300
Gastrointestinal Diseases	Associate	10919775, 11292780, 12682135, 17905877, 21464088, 9431915
Glioblastoma	Inhibit	25356585
Glioblastoma	Associate	39352777
Glucose Metabolism Disorders	Associate	26120850, 32936766
Hypertension	Associate	19593212
Hypogonadism	Associate	26120850, 32936766
Hypoxia	Associate	39352777
Ileal Diseases	Associate	2458970
Ileal Neoplasms	Associate	2458970
Inflammation	Inhibit	31442418
Inflammation	Associate	40596471
Intellectual Disability	Associate	26120850, 32936766
Liver Cirrhosis Biliary	Associate	40596471
Lymphatic Metastasis	Stimulate	23852859
Neoplasm Invasiveness	Associate	21061162
Neoplasm Metastasis	Associate	21061162, 21285511, 2458970, 34511489
Neoplasm Metastasis	Stimulate	31731578
Neoplasms	Associate	16836752, 21061162, 21285511, 23852859, 26803519, 28300077, 31731578, 32675394, 35328535, 39352777
Neoplasms	Stimulate	24006921
Neoplasms	Inhibit	34556748
Neurologic Manifestations	Associate	28114332
Obesity	Associate	12530526, 23900445, 26120850, 32936766
Obesity Morbid	Associate	26120850, 32936766
Oligodendroglioma	Stimulate	21061162
Osteosarcoma	Associate	37663298
Pancreatic Neoplasms	Associate	31731578, 32675394, 33164330, 33253517, 35528956
Pelvic Organ Prolapse	Associate	26545240
Pheochromocytoma	Associate	21061162
Pituitary Neoplasms	Stimulate	21061162
Prostate Cancer Hereditary 7	Inhibit	34556748
Prostatic Neoplasms	Inhibit	34556748
Retinal Perforations	Associate	37530283
Sarcoma Ewing	Stimulate	21061162
Teratoma	Associate	27803193
Testicular Germ Cell Tumor	Associate	27803193

CPE (carboxypeptidase E)