Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
135114
Gene name Gene Name - the full gene name approved by the HGNC.
Histidine triad nucleotide binding protein 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
HINT3
Synonyms (NCBI Gene) Gene synonyms aliases
HINT4
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6q22.32
Summary Summary of gene provided in NCBI Entrez Gene.
Histidine triad proteins, such as HINT3, are nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides (Brenner, 2002 [PubMed 12119013]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024582 hsa-miR-215-5p Microarray 19074876
MIRT026326 hsa-miR-192-5p Microarray 19074876
MIRT028522 hsa-miR-30a-5p Proteomics 18668040
MIRT1046097 hsa-miR-1200 CLIP-seq
MIRT1046098 hsa-miR-122 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0005634 Component Nucleus IMP 17870088
GO:0005737 Component Cytoplasm IMP 17870088
GO:0042802 Function Identical protein binding IDA 17870088
GO:0043530 Function Adenosine 5'-monophosphoramidase activity IDA 17870088
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
609998 18468 ENSG00000111911
Protein
UniProt ID Q9NQE9
Protein name Adenosine 5'-monophosphoramidase HINT3 (EC 3.9.1.-) (Histidine triad nucleotide-binding protein 3) (HINT-3)
Protein function Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:17870088). Hydrolyzes lysyl-AMP (AMP-
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11969 DcpS_C 47 162 Family
Sequence
Sequence length 182
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Narcolepsy Narcolepsy rs104894574, rs387906655 19629137
Associations from Text Mining
Disease Name Relationship Type References
Multiple Sclerosis Associate 34504491