UBLCP1 (ubiquitin like domain containing CTD phosphatase 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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134510 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Ubiquitin like domain containing CTD phosphatase 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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UBLCP1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CPUB1 |
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Chromosome
Chromosome number
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5 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q33.3 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q8WVY7 | |||||||||||||||
| Protein name | Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1) | |||||||||||||||
| Protein function | Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity (PubMed:21949367, PubMed:28539385). Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1 (Pub | |||||||||||||||
| PDB | 2KX3 , 2LGD , 2M17 | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues. {ECO:0000269|PubMed:15883030}. | |||||||||||||||
| Sequence |
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| Sequence length | 318 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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