Gene Gene information from NCBI Gene database.
Entrez ID 134510
Gene name Ubiquitin like domain containing CTD phosphatase 1
Gene symbol UBLCP1
Synonyms (NCBI Gene)
CPUB1
Chromosome 5
Chromosome location 5q33.3
miRNA miRNA information provided by mirtarbase database.
330
miRTarBase ID miRNA Experiments Reference
MIRT019695 hsa-miR-375 Microarray 20215506
MIRT608049 hsa-miR-7106-5p HITS-CLIP 24906430
MIRT608048 hsa-miR-149-3p HITS-CLIP 24906430
MIRT608047 hsa-miR-4728-5p HITS-CLIP 24906430
MIRT608046 hsa-miR-6785-5p HITS-CLIP 24906430
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17
GO ID Ontology Definition Evidence Reference
GO:0004721 Function Phosphoprotein phosphatase activity IEA
GO:0004722 Function Protein serine/threonine phosphatase activity IBA
GO:0004722 Function Protein serine/threonine phosphatase activity IDA 21949367, 28539385
GO:0004722 Function Protein serine/threonine phosphatase activity IEA
GO:0005515 Function Protein binding IPI 16189514, 25416956, 27880917, 32296183, 33961781
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609867 28110 ENSG00000164332
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8WVY7
Protein name Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1)
Protein function Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity (PubMed:21949367, PubMed:28539385). Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1 (Pub
PDB 2KX3 , 2LGD , 2M17
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00240 ubiquitin 5 79 Ubiquitin family Domain
PF03031 NIF 138 301 NLI interacting factor-like phosphatase Family
Tissue specificity TISSUE SPECIFICITY: Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues. {ECO:0000269|PubMed:15883030}.
Sequence
Sequence length 318
Interactions View interactions