SLCO6A1 (solute carrier organic anion transporter family member 6A1)

Gene
Gene Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
133482
Gene name Gene Name - the full gene name approved by the HGNC.
Solute carrier organic anion transporter family member 6A1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SLCO6A1
Synonyms (NCBI Gene) Gene synonyms aliases
CT48, GST, OATP-I, OATP6A1, OATPY
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q21.1
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide all(7)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32814053
GO:0005886 Component Plasma membrane IEA
GO:0015347 Function Sodium-independent organic anion transmembrane transporter activity IBA
GO:0016020 Component Membrane IEA
GO:0016323 Component Basolateral plasma membrane IBA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
613365 23613 ENSG00000205359
Protein
Gene Gene ontology Other IDs Protein Associated diseases
UniProt ID Q86UG4
Protein name Solute carrier organic anion transporter family member 6A1 (Cancer/testis antigen 48) (CT48) (Gonad-specific transporter) (GST) (Organic anion-transporting polypeptide 6A1) (Organic anion-transporting polypeptide I) (OATP-I) (Solute carrier family 21 memb
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03137 OATP 107 → 665 Organic Anion Transporter Polypeptide (OATP) family Family
PF07648 Kazal_2 502 → 549 Kazal-type serine protease inhibitor domain Domain
Tissue specificity TISSUE SPECIFICITY: Strongly expressed in testis. Weakly expressed in spleen, brain, fetal brain and placenta. Detected in lung tumors. {ECO:0000269|PubMed:12677006, ECO:0000269|PubMed:15546177}.
Sequence
Sequence length 719
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Gene Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (3)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Diabetes Type 2 diabetes N/A N/A GWAS
Metabolic Syndrome Metabolic syndrome N/A N/A GWAS
Schizophrenia Schizophrenia N/A N/A GWAS
Show/Hide Text Mining Associations (2)
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Crohn Disease Associate 23071489
Obesity Associate 28489853