Gene Gene information from NCBI Gene database.
Entrez ID 132864
Gene name Cytoplasmic polyadenylation element binding protein 2
Gene symbol CPEB2
Synonyms (NCBI Gene)
CPE-BP2CPEB-2hCPEB-2
Chromosome 4
Chromosome location 4p15.32
Summary The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the
miRNA miRNA information provided by mirtarbase database.
361
miRTarBase ID miRNA Experiments Reference
MIRT003167 hsa-miR-210-3p immunoprecipitaionLuciferase reporter assayMicroarrayqRT-PCR 19826008
MIRT005587 hsa-miR-26a-5p Luciferase reporter assayNorthern blotqRT-PCR 20660482
MIRT005587 hsa-miR-26a-5p Luciferase reporter assayNorthern blotqRT-PCR 20660482
MIRT005590 hsa-miR-92a-3p Luciferase reporter assayNorthern blotqRT-PCR 20660482
MIRT005590 hsa-miR-92a-3p Luciferase reporter assayNorthern blotqRT-PCR 20660482
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
29
GO ID Ontology Definition Evidence Reference
GO:0000900 Function MRNA regulatory element binding translation repressor activity IBA
GO:0000900 Function MRNA regulatory element binding translation repressor activity ISS
GO:0003676 Function Nucleic acid binding IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610605 21745 ENSG00000137449
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7Z5Q1
Protein name Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (hCPEB-2)
Protein function May play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. Binds to poly(U) RNA oligomers (By similarity). Required for cell cycle progression, specifically for the transition from metaphase to
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF16367 RRM_7 331 420 RNA recognition motif Domain
PF16366 CEBP_ZZ 513 576 Cytoplasmic polyadenylation element-binding protein ZZ domain Domain
Sequence
MPPPSPDSENGFYPGLPSSMNPAFFPSFSPVSPHGCTGLSVPTSGGGGGGFGGPFSATAV
PPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLL
KQSPWSNHQSSGWGTGSMSWGAMHGRDHRRTGNMGIPGTMNQISPLKKPFSGNVIAPPKF
TRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRID
QDRSRMYDSLNMHSLENSLIDIMRAEHDPLKGRLSYPHPGTDNLLMLNGRSSLFPIDDGL
LDDGHSDQVGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVV
DWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRP

WNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKY
PKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFA
PFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKE
GADRPRQIHFRWN
Sequence length 589
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Oocyte meiosis
Progesterone-mediated oocyte maturation