LIN54 (lin-54 DREAM MuvB core complex component)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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132660 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Lin-54 DREAM MuvB core complex component |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LIN54 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CXCDC1, JC8.6, MIP120, TCX1 |
Chromosome
Chromosome number
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4 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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4q21.22 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes (Schmit et al., 2009 [PubMed 19725879]).[supplied by OMIM, Dec 2010] |
miRNA
miRNA information provided by mirtarbase database.
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Transcription factors | |||||||
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q6MZP7 | |||||||||||||||
Protein name | Protein lin-54 homolog (CXC domain-containing protein 1) | |||||||||||||||
Protein function | Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context (PubMed:17531812, PubMed:17671431). In G0 phase, the complex binds to more than 800 promoters and is requ | |||||||||||||||
PDB | 5FD3 | |||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 749 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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