Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
131566
Gene name Gene Name - the full gene name approved by the HGNC.
Discoidin, CUB and LCCL domain containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
DCBLD2
Synonyms (NCBI Gene) Gene synonyms aliases
CLCP1, ESDN
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3q12.1|3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT004182 hsa-miR-197-3p Microarray 16822819
MIRT026678 hsa-miR-192-5p Microarray 19074876
MIRT028238 hsa-miR-33a-5p Sequencing 20371350
MIRT029917 hsa-miR-26b-5p Microarray 19088304
MIRT051679 hsa-let-7e-5p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
TFAP2A Activation 22468095
TFAP2A Unknown 20525283
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 23770091
GO:0005887 Component Integral component of plasma membrane IDA 11447234
GO:0009986 Component Cell surface IDA 11447234
GO:0030308 Process Negative regulation of cell growth IDA 11447234
GO:0030522 Process Intracellular receptor signaling pathway NAS 11447234
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608698 24627 ENSG00000057019
Protein
UniProt ID Q96PD2
Protein name Discoidin, CUB and LCCL domain-containing protein 2 (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1) (Endothelial and smooth muscle cell-derived neuropilin-like protein)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00431 CUB 72 184 CUB domain Domain
PF03815 LCCL 187 287 LCCL domain Domain
PF00754 F5_F8_type_C 307 446 F5/8 type C domain Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells. {ECO:0000269|PubMed:11447234, ECO:0000269|PubMed:11973641}.
Sequence
MASRAVVRARRCPQCPQVRAAAAAPAWAALPLSRSLPPCSNSSSFSMPLFLLLLLVLLLL
LEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRVKMGERVRIKFGDFDI
EDSDSCHFNYLRIYNGIGVSRTEIGKYCGLGLQMNHSIESKGNEITLLFMSGIHVSGRGF
LASY
SVIDKQDLITCLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAG
VHAGVVSNTLGGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTF
KTSGCYGTLGMES
GVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKK
ITGIITTGSTMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNF
LPPIIARFIRVNPTQWQQKIAMKMEL
LGCQFIPKGRPPKLTQPPPPRNSNDLKNTTAPPK
IAKGRAPKFTQPLQPRSSNEFPAQTEQTTASPDIRNTTVTPNVTKDVALAAVLVPVLVMV
LTTLILILVCAWHWRNRKKKTEGTYDLPYWDRAGWWKGMKQFLPAKAVDHEETPVRYSSS
EVNHLSPREVTTVLQADSAEYAQPLVGGIVGTLHQRSTFKPEEGKEAGYADLDPYNSPGQ
EVYHAYAEPLPITGPEYATPIIMDMSGHPTTSVGQPSTSTFKATGNQPPPLVGTYNTLLS
RTDSCSSAQAQYDTPKAGKPGLPAPDELVYQVPQSTQEVSGAGRDGECDVFKEIL
Sequence length 775
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Gastric cancer Hereditary Diffuse Gastric Cancer rs137854571, rs63751108, rs34612342, rs121908383, rs121909144, rs121909775, rs121909219, rs121909223, rs63750871, rs80359530, rs121964873, rs121913530, rs606231203, rs121918505, rs587776802
View all (244 more)
18314483
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 34580602
Breast Neoplasms Associate 32526247
Carcinoma Pancreatic Ductal Associate 30092011, 32958051
Cardiomyopathy Restrictive Associate 34145321
Colorectal Neoplasms Associate 24133572, 30537927
Congenital Abnormalities Associate 34145321
Developmental Disabilities Associate 34145321
Disease Progression Associate 22468095
Glaucoma Open Angle Associate 36727359
Inflammation Associate 34580602