AP1S3 (adaptor related protein complex 1 subunit sigma 3)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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130340 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Adaptor related protein complex 1 subunit sigma 3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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AP1S3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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PSORS15, sigma1C |
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Chromosome
Chromosome number
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2 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q36.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q96PC3 | ||||||||||
| Protein name | AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit | ||||||||||
| Protein function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognitio | ||||||||||
| PDB | 4HMY , 6CM9 , 6CRI , 6D83 , 6D84 , 6DFF , 7R4H , 7UX3 , 8D4C , 8D4D , 8D4E , 8D4F , 8D4G , 8D9R , 8D9S , 8D9T , 8D9U , 8D9V , 8D9W | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. | ||||||||||
| Sequence |
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| Sequence length | 154 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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