Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
129787
Gene name Gene Name - the full gene name approved by the HGNC.
Transmembrane protein 18
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TMEM18
Synonyms (NCBI Gene) Gene synonyms aliases
lncND
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p25.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT531415 hsa-miR-548ac PAR-CLIP 22012620
MIRT531413 hsa-miR-548bb-3p PAR-CLIP 22012620
MIRT531412 hsa-miR-548d-3p PAR-CLIP 22012620
MIRT531411 hsa-miR-548h-3p PAR-CLIP 22012620
MIRT531410 hsa-miR-548z PAR-CLIP 22012620
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003677 Function DNA binding IEA
GO:0005737 Component Cytoplasm IEA
GO:0016021 Component Integral component of membrane IEA
GO:0016477 Process Cell migration IDA 18559506
GO:0031965 Component Nuclear membrane IDA 18559506
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
613220 25257 ENSG00000151353
Protein
UniProt ID Q96B42
Protein name Transmembrane protein 18
Protein function Transcription repressor. Sequence-specific ssDNA and dsDNA binding protein, with preference for GCT end CTG repeats. Cell migration modulator which enhances the glioma-specific migration ability of neural stem cells (NSC) and neural precursor ce
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14770 TMEM18 16 133 Transmembrane protein 18 Family
Sequence
Sequence length 140
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)
28869590
Obesity Obesity rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562
View all (27 more)
19079261
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Gout Gout GWAS
Hypertension Hypertension GWAS
Associations from Text Mining
Disease Name Relationship Type References
Abdominal Injuries Associate 31167208
Breast Neoplasms Associate 29073238
Diabetes Mellitus Type 2 Associate 31167208, 32228543
Glucocorticoid Receptor Deficiency Associate 30026463
Kidney Neoplasms Inhibit 33299884
Neoplasms Stimulate 33299884
Neoplasms Adipose Tissue Associate 33491310
Obesity Associate 19164386, 19910938, 20628085, 20724581, 20725061, 21720444, 21779088, 21796137, 21976109, 21980424, 22051089, 22095114, 23347264, 23349760, 23408508
View all (15 more)
Overweight Associate 23347264
Thinness Associate 23890480