Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	129684
Gene name	Contactin associated protein family member 5
Gene symbol	CNTNAP5
Synonyms (NCBI Gene)	caspr5
Chromosome	2
Chromosome location	2q14.3
Summary	This gene product belongs to the neurexin family, members of which function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domai

122

Show/Hide all (122)

miRTarBase ID	miRNA	Experiments	Reference
MIRT707179	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT707178	hsa-miR-4643	HITS-CLIP	21572407
MIRT707177	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT707176	hsa-miR-4798-3p	HITS-CLIP	21572407
MIRT707175	hsa-miR-3680-5p	HITS-CLIP	21572407
MIRT707174	hsa-miR-369-3p	HITS-CLIP	21572407
MIRT707173	hsa-miR-5692b	HITS-CLIP	21572407
MIRT707172	hsa-miR-5692c	HITS-CLIP	21572407
MIRT707171	hsa-miR-1285-5p	HITS-CLIP	21572407
MIRT707170	hsa-miR-16-1-3p	HITS-CLIP	21572407
MIRT707169	hsa-miR-4797-3p	HITS-CLIP	21572407
MIRT707168	hsa-miR-4264	HITS-CLIP	21572407
MIRT707167	hsa-miR-466	HITS-CLIP	21572407
MIRT707166	hsa-miR-374a-5p	HITS-CLIP	21572407
MIRT707165	hsa-miR-374b-5p	HITS-CLIP	21572407
MIRT707164	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT543637	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707163	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT524410	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT524409	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT524408	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT524407	hsa-miR-210-3p	HITS-CLIP	21572407
MIRT524406	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT524410	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT524409	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT524408	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT524407	hsa-miR-210-3p	PAR-CLIP	21572407
MIRT524406	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT524410	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT524408	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT543637	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT524406	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT524410	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT524409	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT524408	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT524407	hsa-miR-210-3p	PAR-CLIP	23446348
MIRT524406	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT707163	hsa-miR-1277-5p	HITS-CLIP	27418678
MIRT707163	hsa-miR-1277-5p	HITS-CLIP	27418678
MIRT543637	hsa-miR-190a-3p	HITS-CLIP	27418678
MIRT543637	hsa-miR-190a-3p	HITS-CLIP	27418678
MIRT524409	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT524409	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT524411	hsa-miR-5011-5p	HITS-CLIP	27418678
MIRT524411	hsa-miR-5011-5p	HITS-CLIP	27418678
MIRT524410	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT524410	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT524406	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT524406	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT524408	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT524408	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT707179	hsa-miR-4789-3p	HITS-CLIP	21572407
MIRT707178	hsa-miR-4643	HITS-CLIP	21572407
MIRT707177	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT707176	hsa-miR-4798-3p	HITS-CLIP	21572407
MIRT707175	hsa-miR-3680-5p	HITS-CLIP	21572407
MIRT707174	hsa-miR-369-3p	HITS-CLIP	21572407
MIRT707173	hsa-miR-5692b	HITS-CLIP	21572407
MIRT707172	hsa-miR-5692c	HITS-CLIP	21572407
MIRT707171	hsa-miR-1285-5p	HITS-CLIP	21572407
MIRT707170	hsa-miR-16-1-3p	HITS-CLIP	21572407
MIRT707169	hsa-miR-4797-3p	HITS-CLIP	21572407
MIRT707168	hsa-miR-4264	HITS-CLIP	21572407
MIRT707167	hsa-miR-466	HITS-CLIP	21572407
MIRT707166	hsa-miR-374a-5p	HITS-CLIP	21572407
MIRT707165	hsa-miR-374b-5p	HITS-CLIP	21572407
MIRT707164	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT543637	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT707163	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT524410	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT524409	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT524408	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT524407	hsa-miR-210-3p	HITS-CLIP	21572407
MIRT524406	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT524410	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT524409	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT524408	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT524407	hsa-miR-210-3p	PAR-CLIP	21572407
MIRT524406	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT524410	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT524408	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT543637	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT524406	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT524411	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT524410	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT524409	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT524408	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT524407	hsa-miR-210-3p	PAR-CLIP	23446348
MIRT524406	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT901899	hsa-miR-1276	CLIP-seq
MIRT901900	hsa-miR-3123	CLIP-seq
MIRT901901	hsa-miR-3180-5p	CLIP-seq
MIRT901902	hsa-miR-3617	CLIP-seq
MIRT901903	hsa-miR-4311	CLIP-seq
MIRT901904	hsa-miR-4724-5p	CLIP-seq
MIRT901905	hsa-miR-4738-3p	CLIP-seq
MIRT901906	hsa-miR-520a-5p	CLIP-seq
MIRT901907	hsa-miR-525-5p	CLIP-seq
MIRT901908	hsa-miR-567	CLIP-seq
MIRT901909	hsa-miR-583	CLIP-seq
MIRT901910	hsa-miR-641	CLIP-seq
MIRT1967533	hsa-miR-31	CLIP-seq
MIRT1967534	hsa-miR-330-3p	CLIP-seq
MIRT901902	hsa-miR-3617	CLIP-seq
MIRT901910	hsa-miR-641	CLIP-seq
MIRT2203269	hsa-miR-103a	CLIP-seq
MIRT2203270	hsa-miR-107	CLIP-seq
MIRT2203271	hsa-miR-1184	CLIP-seq
MIRT901904	hsa-miR-4724-5p	CLIP-seq
MIRT2203272	hsa-miR-4728-3p	CLIP-seq
MIRT2203273	hsa-miR-491-3p	CLIP-seq
MIRT2447418	hsa-miR-148a	CLIP-seq
MIRT2447419	hsa-miR-148b	CLIP-seq
MIRT2447420	hsa-miR-152	CLIP-seq
MIRT901905	hsa-miR-4738-3p	CLIP-seq

Show/Hide all (2)

GO ID	Ontology	Definition	Evidence	Reference
GO:0007155	Process	Cell adhesion	IEA
GO:0016020	Component	Membrane	IEA

MIM	HGNC	e!Ensembl
610519	18748	ENSG00000155052

Q8WYK1

Protein name

Contactin-associated protein-like 5 (Cell recognition molecule Caspr5)

Protein function

May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00754	F5_F8_type_C	42 → 171	F5/8 type C domain	Domain
PF02210	Laminin_G_2	209 → 338	Laminin G domain	Domain
PF02210	Laminin_G_2	395 → 521	Laminin G domain	Domain
PF02210	Laminin_G_2	819 → 938	Laminin G domain	Domain
PF02210	Laminin_G_2	1044 → 1173	Laminin G domain	Domain

Sequence

MDSLPRLTSVLTLLFSGLWHLGLTATNYNCDDPLASLLSPMAFSSSSDLTGTHSPAQLNW
RVGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYSLMFSDTGRNWKQY
KQEDSIWTFAGNMNADSVVHHKLLHSVRARFVRFVPLEWNPSGKIGMRVEVYGCSYKSDV
ADFDGRSSLLYRFNQKLMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLAL
HLNLGDSKARLSSSLPSATLGSLLDDQHWHSVLIERVGKQVNFTVDKHTQHFRTKGETDA
LDIDYELSFGGIPVPGKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSC
SEPQIVPITFVNSSGSYLLLPGTPQIDGLSVSFQFRTWNKDGLLLSTELSEGSGTLLLSL
EGGILRLVIQKMTERVAEILTGSNLNDGLWHSVSINARRNRITLTLDDEAAPPAPDSTWV
QIYSGNSYYFGGCPDNLTDSQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLH
IDLCSIKDRCLPNYCEHGGSCSQSWTTFYCNCSDTSYTGATCHNSIYEQSCEVYRHQGNT
AGFFYIDSDGSGPLGPLQVYCNITEDKIWTSVQHNNTELTRVRGANPEKPYAMALDYGGS
MEQLEAVIDGSEHCEQEVAYHCRRSRLLNTPDGTPFTWWIGRSNERHPYWGGSPPGVQQC
ECGLDESCLDIQHFCNCDADKDEWTNDTGFLSFKDHLPVTQIVITDTDRSNSEAAWRIGP
LRCYGDRRFWNAVSFYTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRL
EISSPSEITFAIDVGNGPVELVVQSPSLLNDNQWHYVRAERNLKETSLQVDNLPRSTRET
SEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKMDLEERAKVTSGVRPGCPGHC
SSYGSICHNGGKCVEKHNGYLCDCTNSPYEGPFCKKEVSAVFEAGTSVTYMFQEPYPVTK
NISLSSSAIYTDSAPSKENIALSFVTTQAPSLLLFINSSSQDFVVVLLCKNGSLQVRYHL
NKEETHVFTIDADNFANRRMHHLKINREGRELTIQMDQQLRLSYNFSPEVEFRVIRSLTL
GKVTENLGLDSEVAKANAMGFAGCMSSVQYNHIAPLKAALRHATVAPVTVHGTLTESSCG
FMVDSDVNAVTTVHSSSDPFGKTDEREPLTNAVRSDSAVIGGVIAVVIFIIFCIIGIMTR
FLYQHKQSHRTSQMKEKEYPENLDSSFRNEIDLQNTVSECKREYFI

Sequence length

1306

Interactions

View interactions

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
CNTNAP5-associated intellectual disability	Uncertain significance	rs982218609	RCV001260250
CNTNAP5-related disorder	Uncertain significance; Likely benign; Benign	rs200361177, rs2467393598, rs2467137992, rs932717603, rs2467590777, rs367708864, rs370802996, rs200964430, rs375299973, rs779127795, rs749556691, rs200562881, rs567929192, rs200688462, rs375524808 View all (15 more)	RCV003966322 RCV003410509 RCV003397450 RCV003410857 RCV003405857 RCV003923838 RCV003929690 RCV003917323 RCV003906812 RCV003924626 RCV003939857 RCV003961459 RCV003951441 RCV003959181 RCV003927383 RCV003979092 RCV003979127 RCV003957254 RCV003935917 RCV003935802 RCV003905786 RCV003926201 RCV003955847 RCV003950372 RCV003940489 RCV003910399 RCV003955916 RCV003913033 RCV003913092 RCV003960857
Gastric cancer	Likely benign	rs192880351	RCV005905864

Show/Hide Text Mining Associations (14)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Alcohol Related Disorders	Associate	34553698
Atrophy	Associate	26993346
Autism Spectrum Disorder	Associate	32807774, 34553698
Autistic Disorder	Associate	20346443
Bipolar Disorder	Associate	24387768
Carcinoma Renal Cell	Associate	32789468
Developmental Disabilities	Associate	34553698
Diabetes Mellitus Type 2	Associate	21423737
Dyslexia	Associate	20346443
Glaucoma Angle Closure	Associate	33737499
Language Development Disorders	Associate	34553698
Malformations of Cortical Development Group I	Associate	33737499
Neurodegenerative Diseases	Associate	33737499
Obesity	Associate	21423737, 34553698

CNTNAP5 (contactin associated protein family member 5)