TBC1D20 (TBC1 domain family member 20)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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128637 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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TBC1 domain family member 20 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TBC1D20 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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C20orf140, WARBM4 |
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Chromosome
Chromosome number
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20 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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20p13 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replica |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q96BZ9 | ||||||||||
| Protein name | TBC1 domain family member 20 | ||||||||||
| Protein function | GTPase-activating protein (GAP) specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude (PubMed:23236136). Also shows GAP activity for RAB18 GTPase (Pub | ||||||||||
| PDB | 4HL4 , 4HLQ | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 403 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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