TSHZ2 (teashirt zinc finger homeobox 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 128553 |
| Gene name | Teashirt zinc finger homeobox 2 |
| Gene symbol | TSHZ2 |
| Synonyms (NCBI Gene) |
C20orf17OVC10-2TSH2ZABC2ZNF218
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| Chromosome | 20 |
| Chromosome location | 20q13.2 |
| Summary | This gene is a member of the teashirt C2H2-type zinc-finger protein family of transcription factors. This gene encodes a protein with five C2H2-type zinc fingers, a homeobox DNA-binding domain and a coiled-coil domain. This nuclear protein is predicted to |
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miRNA
miRNA information provided by mirtarbase database.
570
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9NRE2 | |
| Protein name | Teashirt homolog 2 (Ovarian cancer-related protein 10-2) (OVC10-2) (Zinc finger protein 218) | |
| Protein function | Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease. {ECO:0000269|PubMed:19343227}. | |
| Sequence |
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| Sequence length | 1034 | |
| Interactions | View interactions | |
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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