Gene Gene information from NCBI Gene database.
Entrez ID 128387
Gene name TatD DNase domain containing 3
Gene symbol TATDN3
Synonyms (NCBI Gene)
-
Chromosome 1
Chromosome location 1q32.3
miRNA miRNA information provided by mirtarbase database.
351
miRTarBase ID miRNA Experiments Reference
MIRT1411690 hsa-miR-10a CLIP-seq
MIRT1411691 hsa-miR-10b CLIP-seq
MIRT1411692 hsa-miR-339-5p CLIP-seq
MIRT1411693 hsa-miR-3622a-3p CLIP-seq
MIRT1411694 hsa-miR-3622b-3p CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
10
GO ID Ontology Definition Evidence Reference
GO:0003906 Function DNA-(apurinic or apyrimidinic site) endonuclease activity IDA 36881763
GO:0004518 Function Nuclease activity IEA
GO:0004519 Function Endonuclease activity IEA
GO:0005634 Component Nucleus IEA
GO:0005739 Component Mitochondrion HTP 34800366
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q17R31
Protein name Deoxyribonuclease TATDN3 (EC 3.1.11.-) (EC 3.1.21.-) (DNA-(apurinic or apyrimidinic site) endonuclease TATDN3) (TatD DNase domain containing 3)
Protein function Exhibits 3'-exonuclease activities and apurinic/apyrimidinic (AP) endonuclease (in vitro). Show preferential AP endonuclease activity on double-stranded DNA substrates and 3'- exonuclease activity on single-stranded DNA. {ECO:0000269|PubMed:3688
PDB 2Y1H
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01026 TatD_DNase 9 267 TatD related DNase Domain
Sequence
Sequence length 274
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
1
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Gastric cancer Uncertain significance rs547308130 RCV005932292