ADH5 (alcohol dehydrogenase 5 (class III), chi polypeptide)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 128 |
| Gene name | Alcohol dehydrogenase 5 (class III), chi polypeptide |
| Gene symbol | ADH5 |
| Synonyms (NCBI Gene) |
ADH-3ADHXAMEDSBMFS7FALDHFDHGSH-FDHGSNORHEL-S-60p
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| Chromosome | 4 |
| Chromosome location | 4q23 |
| Summary | This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein for |
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miRNA
miRNA information provided by mirtarbase database.
717
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
1
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
34
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P11766 | |||||||||||||||
| Protein name | Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase class chi chain) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutat | |||||||||||||||
| Protein function | Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione (PubMed:8460164). Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarac | |||||||||||||||
| PDB | 1M6H , 1M6W , 1MA0 , 1MC5 , 1MP0 , 1TEH , 2FZE , 2FZW , 3QJ5 , 8GV3 | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 374 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
4
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