Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
1267
Gene name Gene Name - the full gene name approved by the HGNC.
2'',3''-cyclic nucleotide 3'' phosphodiesterase
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CNP
Synonyms (NCBI Gene) Gene synonyms aliases
CN37, CNP1, HLD20
Disease Acronyms (UniProt) Disease acronyms from UniProt database
HLD20
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q21.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022857 hsa-miR-124-3p Proteomics;Microarray 18668037
MIRT051255 hsa-miR-16-5p CLASH 23622248
MIRT049951 hsa-miR-30a-5p CLASH 23622248
MIRT042728 hsa-miR-345-5p CLASH 23622248
MIRT040114 hsa-miR-615-3p CLASH 23622248
Transcription factors
Transcription factor Regulation Reference
TSC22D1 Activation 20802130
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000226 Process Microtubule cytoskeleton organization IEA
GO:0003723 Function RNA binding IEA
GO:0004113 Function 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IBA 21873635
GO:0005515 Function Protein binding IPI 17500595, 32814053
GO:0005615 Component Extracellular space IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
123830 2158 ENSG00000173786
Protein
UniProt ID P09543
Protein name 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) (CNPase) (EC 3.1.4.37)
Protein function Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates (By similarity). May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity). {
PDB 1WOJ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13671 AAA_33 52 175 Domain
PF05881 CNPase 186 420 Family
Sequence
Sequence length 421
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
18289148, 17964117, 23032943, 24788877, 19348671
Unknown
Disease term Disease name Evidence References Source
Mental depression Unipolar Depression, Major Depressive Disorder 22832658 ClinVar
Leukodystrophy leukodystrophy, hypomyelinating, 20 GenCC
Associations from Text Mining
Disease Name Relationship Type References
Achondroplasia Associate 28661490, 34930956
Arthritis Rheumatoid Associate 33653372
Atherosclerosis Associate 34308964
Bipolar Disorder Associate 25539505
Carcinoma Hepatocellular Inhibit 34352718
CATSHL syndrome Associate 30032985
Genetic Diseases Inborn Associate 34930956
Heart Failure Associate 25117468
Hepatitis B Chronic Associate 24260477
HIV Infections Associate 26033855