CNN2 (calponin 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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1265 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Calponin 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CNN2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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19 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||||||||||||
UniProt ID | Q99439 | |||||||||||||||||||||||||
Protein name | Calponin-2 (Calponin H2, smooth muscle) (Neutral calponin) | |||||||||||||||||||||||||
Protein function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-A | |||||||||||||||||||||||||
PDB | 1WYN | |||||||||||||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Heart and smooth muscle. | |||||||||||||||||||||||||
Sequence |
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Sequence length | 309 | |||||||||||||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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