WDR88 (WD repeat domain 88)

Gene

• Entrez ID: 126248
• Gene name: WD repeat domain 88
• Gene symbol: WDR88
• Synonyms (NCBI Gene): PQWD
• Chromosome: 19
• Chromosome location: 19q13.11

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1491897	hsa-miR-3136-3p	CLIP-seq
MIRT1491898	hsa-miR-3184	CLIP-seq
MIRT1491899	hsa-miR-3192	CLIP-seq
MIRT1491900	hsa-miR-3660	CLIP-seq
MIRT1491901	hsa-miR-3689a-3p	CLIP-seq
MIRT1491902	hsa-miR-3689c	CLIP-seq
MIRT1491903	hsa-miR-370	CLIP-seq
MIRT1491904	hsa-miR-423-5p	CLIP-seq
MIRT1491905	hsa-miR-4526	CLIP-seq
MIRT1491906	hsa-miR-4650-5p	CLIP-seq
MIRT1491907	hsa-miR-4663	CLIP-seq
MIRT1491908	hsa-miR-4728-5p	CLIP-seq
MIRT1491909	hsa-miR-661	CLIP-seq
MIRT1491897	hsa-miR-3136-3p	CLIP-seq
MIRT1491898	hsa-miR-3184	CLIP-seq
MIRT1491899	hsa-miR-3192	CLIP-seq
MIRT1491901	hsa-miR-3689a-3p	CLIP-seq
MIRT1491902	hsa-miR-3689c	CLIP-seq
MIRT1491903	hsa-miR-370	CLIP-seq
MIRT1491904	hsa-miR-423-5p	CLIP-seq
MIRT1491906	hsa-miR-4650-5p	CLIP-seq
MIRT1491907	hsa-miR-4663	CLIP-seq
MIRT1491908	hsa-miR-4728-5p	CLIP-seq
MIRT2463482	hsa-miR-518a-5p	CLIP-seq
MIRT2463483	hsa-miR-527	CLIP-seq
MIRT1491909	hsa-miR-661	CLIP-seq
MIRT2662295	hsa-miR-1287	CLIP-seq
MIRT2662296	hsa-miR-1289	CLIP-seq
MIRT2662297	hsa-miR-1914	CLIP-seq
MIRT2662298	hsa-miR-196a	CLIP-seq
MIRT2662299	hsa-miR-196b	CLIP-seq
MIRT2662300	hsa-miR-3135b	CLIP-seq
MIRT2662301	hsa-miR-3198	CLIP-seq
MIRT2662302	hsa-miR-3927	CLIP-seq
MIRT2662303	hsa-miR-4293	CLIP-seq
MIRT2662304	hsa-miR-4294	CLIP-seq
MIRT2662305	hsa-miR-4309	CLIP-seq
MIRT2662306	hsa-miR-596	CLIP-seq
MIRT2662307	hsa-miR-668	CLIP-seq

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q6ZMY6
• Protein name: WD repeat-containing protein 88 (PQQ repeat and WD repeat-containing protein)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00400	WD40	93 → 130	WD domain, G-beta repeat	Repeat
  PF01011	PQQ	159 → 191	PQQ enzyme repeat	Repeat
  PF00400	WD40	219 → 258	WD domain, G-beta repeat	Repeat
  PF00400	WD40	263 → 301	WD domain, G-beta repeat	Repeat
  PF00400	WD40	311 → 349	WD domain, G-beta repeat	Repeat
  PF00400	WD40	354 → 391	WD domain, G-beta repeat	Repeat

• Sequence:

  MASPPRCSPTAHDRECKLPPPSAPASEYCPGKLSWGTMARALGRFKLSIPHTHLLATLDP
  LALDREPPPHLLPEKHQVPEKLIWGDQDPLSKIPFKILSGHEHAVSTCHFCVDDTKLLSG
  SYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDLETGKLL
  WKVRYDTFIVSCKFSPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDP
  DSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIW
  NVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLK
  GHNDWVMDVAISNNKKWILSASKDRTMRLWNIEEIDEIPLVIKYKKAVGLKLKQCERCDR
  PFSIFKSDTSSEMFTQCVFCRIDTRGLPADTSSSSSSSERENSPPPRGSKDD

• Sequence length: 472

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243

Unknown
Disease term	Disease name	Evidence	References	Source
Prostate cancer	Prostate cancer	Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population.		GWAS, CBGDA
Alzheimer disease	Alzheimer disease			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Candidiasis	Associate	36167494